Eperythrozoon Coccoides, eine neue durch Splenektomie Aktivierbare Dauerinfektion der Weissen Maus

Malária experimental: contaminação de cepas e animais de biotério por eperythrozoon coccoides

“…Um dos parasitas frequentemente implicado em contaminações acidentais é o Eperythrozoon coccoides 12 , um hemoparasita do sangue de roedores que vive na superfície de hemácias e no plasma de roedores, em particular camundongos 3. A transmissão é feita através de materiais contendo sangue infectado, sendo de transmissibilidade muito alta, bastando uma hemácia contaminada para dar início à infecção 7 .…”

Phylogenetic analysis and description of Eperythrozoon coccoides, proposal to transfer to the genus Mycoplasma as Mycoplasma coccoides comb. nov. and Request for an Opinion

“…Eperythrozoon coccoides is a blood parasite of laboratory and wild mice and was one of the first discovered members (Schilling, 1928;Dinger, 1928Dinger, , 1929 of what has emerged as a large and ubiquitous group of haemotrophic bacteria that infect a broad range of mammalian hosts including, occasionally, humans (Weinman, 1935(Weinman, , 1944Kreier et al, 1992;Neimark et al, 2001). E. coccoides, like most members of the group, is vector-transmitted and produces a primary acute infection which is followed by a persistent latent infection.…”

“…coccoides was first identified in laboratory mice (Schilling, 1928;Dinger, 1928) but wild mice probably are natural hosts (Bruymoghe & Vassiliadis, 1929a, b), and rats and rabbits have been infected experimentally (Bruymoghe & Vassiliadis, 1929c;Eliot & Ford, 1930). Natural infections with E. coccoides are transmitted by adults and nymphs of the lice Polypax spinulosa (Eliot,1936) and Polyplax serrata, which can transmit an infection after fasting for as long as 24 h (Weinman, 1944;Berkenkamp & Wescott, 1988); there is no evidence of E. coccoides replication in lice and transmission appears to be mechanical.…”

“…Splenomegaly also persists in carrier mice presumably as long as they are infected (Baker et al, 1971) and low numbers of organisms may appear sporadically for brief periods in the peripheral blood of chronic carriers (Thurston, 1955). The existence of a latent infection is usually revealed by splenectomy which results in the reappearance of large numbers of organisms in the peripheral blood within 48 h; lower numbers of organisms then persist in the peripheral blood for several months (Schilling, 1928;Eliot & Ford, 1930;McCluskie & Niven, 1934;Marmorston, 1935;Thurston, 1954Thurston, , 1955.…”

“…(i) Eperythrozoon (Schilling, 1928) predates Mycoplasma (Nowak, 1929), consequently under Rules 15, 17, 44 and 51b the name of the united genus should be Eperythrozoon. We request an exception to the rules that would require renaming Mycoplasma species to Eperythrozoon, since changing the names of more than 100 Mycoplasma species to Eperythrozoon (as well as changing the order and family names from Mycoplasmatales and Mycoplasmataceae) would produce enormous confusion.…”