Epibulbar osseous choristoma: A case report

Harkins, Keegan; Perry, Deborah; Suh, Donny W.

doi:10.1016/j.ajoc.2016.10.002

Cited by 14 publications

(9 citation statements)

References 6 publications

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“…Normally, they appear isolated and positioned in the supero-temporal quadrant, however, they can occasionally be present on other locations on the surface of the eye [ [12] , [13] , [14] ]. A pioneer in ophthalmology, Albrecht Von Graefe was the first to describe choristomas in1863, later on in 1964, Beckman and Sugar used the terminology of “osseous choristoma”, as it is recognized currently [ 7 , 15 , 16 ]. Nowadays, and according to our PubMed-based literature research, 65 documented reports only were found since then.…”

Section: Discussionmentioning

confidence: 99%

Epibulbar complex and osseous choristoma: Clinicopathological study with interesting associations

Aldossary

Alkatan

Maktabi

2018

Annals of Medicine and Surgery

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Materials and methodsA retrospective cohort study of cases with tissue diagnosis of epibulbar choristoma in 2 centers presenting during the period: 2000–2016 with focus on cases of complex and osseous choristoma. Demographic and clinical data were collected by the resident from medical records. The histopathological slides were reviewed by 2 pathologists and cases of complex and osseous choristoma were analyzed by biostatical staff.Results120 epibulbar choristomas were identified. 13/120 patients (10.8%) with complex choristoma and 2/120 patients (1.7%) with osseous choristoma. 15 cases were further analyzed: 7 were males and 8 were females. Mean age at presentation was 7.6 year. Commonest location was temporal in 66.6%. The presence of smooth muscle component was associated with a larger size choristoma (p = 0.042). 73.3% had other ophthalmic manifestations (mostly eyelid anomalies) while 9 systemic associations (mostly Goldenhar's syndrome) were found in 8/13 cases of complex choristoma.ConclusionEpibulbar complex and osseous choristomas are rare. Histopathologically, the presence of smooth muscle significantly correlates with the lesion size. Complex choristoma is more likely to be associated with systemic manifestations. Further genetic studies for this condition are recommended.

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Section: Discussionmentioning

confidence: 99%

Epibulbar complex and osseous choristoma: Clinicopathological study with interesting associations

Aldossary

Alkatan

Maktabi

2018

Annals of Medicine and Surgery

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“…[ 27 ] In some cases where it brings recurrent conjunctival hyperemia or ocular foreign body sensation, surgical excision may be indicated. [ 3 ] Surgical excision of a mass located at supratemporal side requires particular attention not to injure adjacent superior and lateral rectus muscles and lacrimal gland ductile. Once surgical excision is planned, pre-operative computed tomography (CT) can be helpful in determining whether the mass involves nearby structures such as sclera or extraocular muscles.…”

Section: Discussionmentioning

confidence: 99%

Epibulbar osseous choristoma with dermolipoma: A case report and review of literature

et al. 2022

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Background: A choristoma is defined as a growth of histologically normal tissue in an abnormal location. Epibulbar osseous choristoma is the rarest type among all ocular choristoma with less than 100 cases reported. Here, we report a case of epibulbar osseous choristoma combined with dermolipoma and a literature review Methods: A 15-year-old female patient presented with an accidentally found subconjunctival mass in her left eye. Slit lamp examination revealed a 10 × 10 mm elevated, sigmoid-shaped mass in the supratemporal quadrant of the bulbar conjunctiva. We performed a debulking excisional biopsy of the mass. Results: The pathology confirmed osseous tissue surrounded by mature adipose tissue. At 1 week after the operation, the wound was clear and the patient was satisfied with the treatment. A systematic literature review of 14 previously published cases taken from PubMed dating back to 1987 along with ours was undertaken. The average age at presentation was 11.6 years and there was a female preponderance with 10 cases being female and the other 5 cases being male. Supratemporal conjunctiva was the most common site of presentation. There was no systemic disease associated with any of the cases. Since it is a benign tumor, it can be managed by observation, but if necessary, it can be treated by surgical removal. Conclusion: In pediatric subconjunctival mass, particularly located in supratemporal quadrant of bulbar conjunctiva, osseous choristoma should be considered in the differential diagnosis. Pre-operative CT scans will helpful to not also reduce complication with surgical excision but also helpful in prediction of diagnosis and prognosis.

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“…Giant papillae may resemble another form of conjunctival mass and can make diagnosis difficult. The differential diagnosis of a pediatric conjunctival mass includes dermolipoma, reactive lymphoid hyperplasia, juvenile xanthogranuloma, extratarsal chalazion, pyogenic granuloma, lymphangioma, hemangioma, hamartoma, histiocytoma, melanoma, rhabdomyosarcoma, epibulbar schwannoma, and choristoma (17)(18)(19)(20)(21)(22)(23)(24)(25)(26)(27)(28)(29)(30)(31). These tumors are grouped into 2 major categories: congenital and acquired lesions.…”

Section: Discussionmentioning

confidence: 99%

“…These tumors are grouped into 2 major categories: congenital and acquired lesions. Acquired lesions are further subdivided based on origin of the mass into surface epithelial, melanocytic, vascular, fibrous, neural, histiocytic, myxoid, myogenic, lipomatous, lymphoid, leukemic, metastatic, and secondary tumors (17)(18)(19)(20)(21)(22)(23)(24)(25)(26)(27)(28)(29)(30)(31).…”

Section: Discussionmentioning

confidence: 99%

Giant papillae prolapse from the upper tarsal conjunctiva in a 3-year-old child: A case presentation and a brief literature review

Kurtul¹

2021

Beyoglu Eye J

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Giant papillae (1.0 mm or greater in diameter) on the upper tarsal conjunctiva are one of the most common findings in cases of vernal keratoconjunctivitis (VKC). Presently described is the case of a 3-year-old female with a unilateral giant papilla formation prolabing from the medial side of the upper tarsal conjunctiva toward the ocular surface in the left eye. A brief review of the recent literature concerning the etiology, associated risk factors, surgical options, and management of patients with giant papillae is also discussed. A significant reduction in the size of the papilla was observed after a week of medical treatment with a topical steroid and antiallergic eye drops. To the best of our knowledge, this case demonstrates the first time that a giant papilla appeared in the form of a prolapsed mass extending from the tarsal conjunctiva in a child with VKC. Ophthalmologists should keep in mind that a giant papilla can look like another form of conjunctival mass, and should not rush to excise or biopsy, as it may respond to medical treatment.

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Epibulbar osseous choristoma: A case report

Cited by 14 publications

References 6 publications

Epibulbar complex and osseous choristoma: Clinicopathological study with interesting associations

Epibulbar complex and osseous choristoma: Clinicopathological study with interesting associations

Epibulbar osseous choristoma with dermolipoma: A case report and review of literature

Giant papillae prolapse from the upper tarsal conjunctiva in a 3-year-old child: A case presentation and a brief literature review

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