Epicardial adipose tissue volume, plaque vulnerability and myocardial ischemia in non-obstructive coronary artery disease

Khan, Ingela; Berge, Christ; Eskerud, Ingeborg; Larsen, Terje H.; Pedersen, Eva Ringdal; Lønnebakken, Mai Tone

doi:10.1016/j.ijcha.2023.101240

IJC Heart & Vasculature

2023

DOI: 10.1016/j.ijcha.2023.101240

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Epicardial adipose tissue volume, plaque vulnerability and myocardial ischemia in non-obstructive coronary artery disease

Ingela Khan

Christ Berge

Ingeborg Eskerud

et al.

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Non-invasive physiological assessment of coronary artery obstruction on coronary computed tomography angiography

Becker,

Peper,

van Nes

et al. 2024

Neth Heart J

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Computed tomography-derived fractional flow reserve (CT-FFR) enhances the specificity of coronary computed tomography angiography (CCTA) to that of the most specific non-invasive imaging techniques, while maintaining high sensitivity in stable coronary artery disease (CAD). As gatekeeper for invasive coronary angiography (ICA), use of CT-FFR results in a significant reduction of negative ICA procedures and associated costs and complications, without increasing cardiovascular events. It is expected that CT-FFR algorithms will continue to improve, regarding accuracy and generalisability, and that introduction of new features will allow further treatment guidance and reduced invasive diagnostic testing. Advancements in CCTA quality and artificial intelligence (AI) are starting to unfold the incremental diagnostic and prognostic capabilities of CCTA’s attenuation-based images in CAD, with future perspectives promising additional CCTA parameters which will enable non-invasive assessment of myocardial ischaemia as well as CAD activity and future cardiovascular risk. This review discusses practical application, interpretation and impact of CT-FFR on patient care, and how this ties into the CCTA ‘one stop shop’ for coronary assessment and patient prognosis. In this light, selective adoption of the most promising, objective and reproducible techniques and algorithms will yield maximal diagnostic value of CCTA without overcomplicating patient management and guideline recommendations.

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Non-invasive physiological assessment of coronary artery obstruction on coronary computed tomography angiography

Becker,

Peper,

van Nes

et al. 2024

Neth Heart J

View full text Add to dashboard Cite

show abstract

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Epicardial adipose tissue volume, plaque vulnerability and myocardial ischemia in non-obstructive coronary artery disease

Cited by 1 publication

References 46 publications

Non-invasive physiological assessment of coronary artery obstruction on coronary computed tomography angiography

Non-invasive physiological assessment of coronary artery obstruction on coronary computed tomography angiography

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