Abstract:Coronary artery disease (CAD) represents the major cause of mortality and long-term disability worldwide. Despite new improvements in primary and secondary prevention methods, CAD-related mortality and morbidity demonstrate an increasing trend in the last decades. [1][2][3] CAD represents the most common and severe consequence of atherosclerosis. 4 Atherosclerotic plaque rupture, leading to acute coronary syndromes as the most severe outcome, consists in a complex biomechanical process resulting from the inter… Show more
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