A longstanding approach to the dynamics of extended objects in curved space-time is given by the Mathisson-Papapetrou-Dixon (MPD) equations of motion for the so-called "pole-dipole approximation." This paper describes an analytic perturbation approach to the MPD equations via a power series expansion with respect to the particle's spin magnitude, in which the particle's kinematic and dynamical degrees of freedom are expressible in a completely general way to formally infinite order in the expansion parameter, and without any reference to pre-existent spacetime symmetries in the background. An important consequence to emerge from the formalism is that the particle's squared mass and spin magnitudes can shift based on a classical analogue of "radiative corrections" due to spin-curvature coupling, whose implications are investigated. It is explicitly shown how to solve for the linear momentum and spin angular momentum for the spinning particle, up to second order in the expansion. As well, this paper outlines two distinct approaches to address the study of many-body dynamics of spinning particles in curved space-time. The first example is the spin modification of the Raychaudhuri equation for worldline congruences, while the second example is the computation of neighbouring worldlines with respect to an arbitrarily chosen reference worldline.