Epidemic Pleurodynia in Texas

Homologous and Heterologous Complement Fixing Antibody in Persons Infected with ECHO, Coxsackie and Poliomyelitis Viruses

“…A study of heterologous C F antibody responses in persons naturally or experimentally infected with ECHO virus types 10, 16, and 20, Coxsackie B virus type 3 , or poliovirus type 1 , indicated an antigenic relationship between the following viruses: ECHO types 2, 4, 5, 6,7,8,11,14,16 R,C 9/10 8 8 A study of heterologous C F antibody responses in persons naturally or experimentally infected with ECHO virus types 10, 16, and 20, Coxsackie B virus type 3 , or poliovirus type 1 , indicated an antigenic relationship between the following viruses: ECHO types 2, 4, 5, 6,7,8,11,14,16 R,C 9/10 8 8 …”

Unusual cause of chest pain, Bornholm disease, a forgotten entity; case report and review of literature

“…First described in Daae and Homann in Norway, disease has been known with many forenames such as Bornholm (City in Denmark) disease, Devil's grippe, epidemic myalgia and epidemic pleurodynia [ 8 ]. However in the early years there was no identifiable pathogen associated with the disease.…”

“…Ever since multiple studies have described the association of Bornholm disease with Coxsackievirus B (CBV) and less frequently echovirus types 1, 6, 8, 9 and 19 and further less frequently with coxsackievirus A (CAV) types 4, 6, 9 and 10 [ 11 , 12 ]. Typical presentation with excruciating pleuritic chest pain or epigastric pain, fevers and complete recovery with supportive care is the norm [ 8 , 11 , [13] , [14] , [15] ]. Characteristic positive history with negative objective findings makes this malady easily distinguishable.…”

The Coxsackie Viruses

“…Huebner and co-workers studied an outbreak of pleurodynia in Texas in 19.51; again B3 was isolated. 42 In an outbreak in Oxford in 1951, 5 per cent of the patients developed aseptic meningitis a t the end of the first week;43 onethird suffered relapse which seems to be characteristic of the disease. I t is now a known fact but was first noted by Gsell in 1949 that the incidence of aseptic meningitis in Bornholm disease is higher in children, and also that most children with aseptic meningitis due to Coxsackie B viruses do not show any symptoms characteristic of ple~rodynia?~ B3 was recovered from an encephalitis outbreak in Sydney, Australia, in 1951, residual weakness persisting in a few patients.…”