Epidemiological analysis of single center of acute poisoning cases based on poisoning treatment platform

Shen, Jun-Hua; Zhang, Jinsong; Qiao, Li; Wang, Lei; Zhu, Bin; Li, Jia; Liu, Ying; Jian-Rong, Cheng

doi:10.1097/md.0000000000026444

Cited by 4 publications

(3 citation statements)

References 7 publications

(13 reference statements)

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“…[ 18 ] In another study in China, 53.96% of patients with acute poisoning were women and 59.23% of patients were 40 years and older. [ 19 ] The mean age of poisoning patients was 26.21 years and 50.3% of them were women in a 10-year study conducted. [ 20 ] Finally, Masoumi et al .…”

Section: Discussionmentioning

confidence: 99%

Comparative Study of Demographic and Toxico-Clinical Factors of Patients with Acute Poisoning Admitted to General Intensive Care Unit Versus Specific Intensive Care Unit for Poisoning Cases

Nemati,

Mirzaee,

Babak

et al. 2023

Advanced Biomedical Research

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Background: There is no dedicated specific intensive care unit (ICU) for poisoning cases due to the small number of poisoned patients in some poisoning centers and patients may hospitalized in the general ICU. In this study, we compared the outcome of hospitalization in poisoning and general ICU, in matched patients to demographical and toxico-clinical factors. Materials and Methods: This historical cohort study was conducted from September 2020 to January 2022 in the general and poisoning ICUs of Khorshid Hospital affiliated to the University of Medical Sciences, Isfahan, Iran. Patient characteristics, clinical, and toxicological information as well as the therapeutic measures and outcome were collected from hospital medical records and analyzed. Results: Totally, 178 (60.1% male and 39.9% female) patients met inclusion criteria. Medicines (56.2%) and opioids (25.3%) followed by pesticides (14%) were the most common substances. Suicide was the type of exposure in 78.7% of the cases. Most patients suffered from lung (19.1%) and kidney (15.2%) injuries. The mortality rate was 23.6%. The median length of hospital stay ( P -value < 0.001) and duration of ventilator usage was higher ( P -value < 0.001) in general ICU compared to specific ICU for poisoning cases. No significant difference with respect to demographic, toxico-clinical variables and mortality rate was found between the two groups. Conclusion: Among poisoned patients admitted to ICU, reported mortality rate was relatively high. Patients who hospitalized in the specific ICU for poisoning cases have lower length of hospital stay and duration of mechanical ventilation compared to general ICU.

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Section: Discussionmentioning

confidence: 99%

Comparative Study of Demographic and Toxico-Clinical Factors of Patients with Acute Poisoning Admitted to General Intensive Care Unit Versus Specific Intensive Care Unit for Poisoning Cases

Nemati,

Mirzaee,

Babak

et al. 2023

Advanced Biomedical Research

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“…In recent years, acute poisoning patterns have changed from country to country [ 5 , 6 ]. Therefore, to lower the incidence of acute poisoning and mortality in children, the causes, frequency, and circumstances of poisoning, as well as the factors that influence the death rate caused by acute poisoning, must be analyzed in different countries and regions.…”

Section: Introductionmentioning

confidence: 99%

Childhood Acute Poisoning at Haiphong Children’s Hospital: A 10-Year Retrospective Study

Nguyen,

Vu,

Nguyen

et al. 2023

International Journal of Pediatrics

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Introduction. Children are most often harmed by acute poisoning, which may cause disability or even death. This demonstrates the critical necessity for epidemiologic studies specific to each nation and area since they aid in developing plans for the prevention of acute poisoning. There are no data or outdated data on acute poisoning in children in Vietnam. This research would partly fill this existing gap and compare the trend with other places across the globe. Methods. A retrospective study was conducted in the 10-year period from 2012 to 2021 in Haiphong Children’s Hospital, Vietnam. Results. There were 771 children hospitalized due to acute poisoning. Children in the 1–5-year-old group accounted for the highest rate, at 506 (65.6%). The mean age was 4.5 ± 4.1 years old. The male-to-female ratio was 1.2/1. Nonpharmaceutical chemicals were the most common agent in 331 cases (42.9%), including cleaning products 63 (19.0%), rat poison 60 (18.1%), and petrol 42 (12.7%). Medications were the second most common agent in 290 cases (37.6%), mostly paracetamol 60 (20.7%) and sedatives 40 (13.8%). There were 633 (82.1%) children exposed to poisons unintentionally. Conclusion. Children between the ages of 1 and 5 are more likely to be exposed to harmful substances. The most common agents were nonpharmaceutical chemicals followed by pharmaceuticals. Most incidents were inadvertent. Finally, our research may provide insights that public health authorities might use to plan practical actions.

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“…Meanwhile, acute poisoning is the most common type in the emergency departments worldwide and is classified into unintentional or intentional categories (6). According to the National Health Commission of China, poisoning and injuries are the top five causes of mortality in this country, accounting for 10.7% of all deaths (7). Based on statistics, over 100,000 people with acute poisoning visit the emergency departments of the UK annually (8).…”

Section: Introductionmentioning

confidence: 99%

Providing a Population Based Registry Model of Drug Poisoning in Iran

et al. 2022

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Background: The prevalence of drug poisoning is on the rise in Iran due to the increased public access to drugs. A national drug poisoning registry system is a suitable tool for better management, control, and prevention of drug poisoning. Objectives: This study aimed to propose a national drug poisoning registry model for Iran. Methods: This was an applied research conducted in two major phases. In the first phase, all sources pertaining to drug poisoning registries were reviewed, and a national drug poisoning registry model was proposed. In the second phase, this model was validated and finalized using a researcher-made questionnaire and through a two-stage Delphi technique. Results: The focus of national drug poisoning activities and registry management reached the 100% consensus of experts at the Drug and Poison Information Center of the Food and Drug Organization (Ministry of Health and Medical Education). Goals, data sources, registry system structure, data set, standards, data exchange, registry features, and processes of the proposed model also achieved unanimous expert consensus. Conclusions: Given the importance of a national drug poisoning registry in gathering, storing, analyzing, and reporting the data of patients, it is essential to provide a framework for evaluating and controlling drug poisoning and for generating valuable data for decision-making. The model proposed herein can offer the information infrastructure for designing and implementing such a system.

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Epidemiological analysis of single center of acute poisoning cases based on poisoning treatment platform

Cited by 4 publications

References 7 publications

Comparative Study of Demographic and Toxico-Clinical Factors of Patients with Acute Poisoning Admitted to General Intensive Care Unit Versus Specific Intensive Care Unit for Poisoning Cases

Comparative Study of Demographic and Toxico-Clinical Factors of Patients with Acute Poisoning Admitted to General Intensive Care Unit Versus Specific Intensive Care Unit for Poisoning Cases

Childhood Acute Poisoning at Haiphong Children’s Hospital: A 10-Year Retrospective Study

Providing a Population Based Registry Model of Drug Poisoning in Iran

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