Epidemiological and bacteriological profiles in children with burns

Hassen, A. Fekih; Khalifa, S. Ben; Daiki, Mayssa

doi:10.1016/j.burns.2013.10.020

Cited by 18 publications

(10 citation statements)

References 31 publications

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“…We therefore retrospectively reviewed the patient data of our burns PICU for a period of 96 months and included 74 patients. The predominance of children aged 5 years and below, male gender, distribution of TBSA and burn injury type was in similar to previous studies [9,13,14]. In our whole cohort, Gram-positive bacteria occurred more frequently than Gram-negative ones, with CNS, Gram-positive mixed flora, and Staphylococcus aureus forming the majority of isolated bacterial groups and strains.…”

Section: Discussionsupporting

confidence: 90%

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Antimicrobial Chemotherapy has a Linear Relationship to the Proportion of Gram-Negative Isolates from Pediatric Burn Wounds

et al. 2018

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Section: Discussionsupporting

confidence: 90%

“…Among the most frequently isolated bacteria, only one Gram-negative organism could be found, P. aeruginosa. A pattern that had been observed in previous studies, too [10,13,14].…”

Section: Discussionsupporting

confidence: 81%

Antimicrobial Chemotherapy has a Linear Relationship to the Proportion of Gram-Negative Isolates from Pediatric Burn Wounds

et al. 2018

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“…Our study also showed the same tendency, that is, dominance of gram-positive infections in children with burns. Two different studies from Tunisia reported that the most common isolated microorganisms were methicillin-sensitive S. aureus (57.7%) and S. aureus (36.3%) in children with burns [14,15]. Moreover, Gang et al reported that 74% of patients with sepsis had bacteremia due to Staphylococcus species [16].…”

Section: Discussionmentioning

confidence: 97%

Burn-associated bloodstream infections in pediatric burn patients: Time distribution of etiologic agents

Devrim

Kara

Düzgöl

et al. 2017

Burns

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“…aureus that nonetheless are commonly involved in infectious complications of burn wounds is a limitation to this study. Gram-negative bacteria such as Pseudomonas aeruginosa and Acinetobacter baumannii have been reported to frequently cause nosocomial infections in burn patients and may have antimicrobial resistance patterns severely limiting the treatment options in this health care setting [44–47]. Of note, hospital hygiene measures in the burn unit were not assessed in the present study.…”

Section: Discussionmentioning

confidence: 99%

Epidemiology of Staphylococcus aureus in a burn unit of a tertiary care center in Ghana

et al. 2017

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BackgroundIn developing countries, hospitalized burn victims are at high risk of nosocomial infections caused by Staphylococcus aureus. Risk factors include poor infection control practices, prolonged hospitalisation and limited capacity for laboratory microbiological analyses. These problems are compounded by widespread use of antibiotics that drives the spread of multi-drug resistant bacteria.MethodsDuring the study period (November 2014-June 2015), nasal and invasive S. aureus isolates were collected consecutively from patients and healthcare workers (HCWs) within the burn unit of the Reconstructive Plastic Surgery and Burn Center of Korle Bu Teaching Hospital in Ghana. Antibiotic prescription, antibiotic susceptibility and bacterial typing were used to assess antibiotic pressure, antibiotic resistance, and possible transmission events among patients and HCWs.ResultsEighty S. aureus isolates were obtained from 37 of the 62 included burn patients and 13 of the 29 HCWs. At admission, 50% of patients carried or were infected with S. aureus including methicillin resistant S. aureus (MRSA). Antibiotic use per 100 days of hospitalization was high (91.2 days), indicating high selective pressure for resistant pathogens. MRSA isolates obtained from 11 patients and one HCW belonged to the same spa-type t928 and multi-locus sequence type 250, implying possible transmission events. A mortality rate of 24% was recorded over the time of admission in the burn unit.ConclusionThis study revealed a high potential for MRSA outbreaks and emergence of resistant pathogens amongst burn patients due to lack of patient screening and extended empirical use of antibiotics. Our observations underscore the need to implement a system of antibiotic stewardship and infection prevention where microbiological diagnostics results are made available to physicians for timely and appropriate patient treatment.

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Epidemiological and bacteriological profiles in children with burns

Cited by 18 publications

References 31 publications

Antimicrobial Chemotherapy has a Linear Relationship to the Proportion of Gram-Negative Isolates from Pediatric Burn Wounds

Antimicrobial Chemotherapy has a Linear Relationship to the Proportion of Gram-Negative Isolates from Pediatric Burn Wounds

Burn-associated bloodstream infections in pediatric burn patients: Time distribution of etiologic agents

Epidemiology of Staphylococcus aureus in a burn unit of a tertiary care center in Ghana

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