Epidemiological and clinical profile of acute coronary syndrome of Egyptian patients admitted to the Coronary Care Unit, Al-Azhar University Hospital, New Damietta

Bashandy, Mohamed A.; Elgalil, Heba Mohammed Abd; Elhassan, Hanaa A.E.A

doi:10.4103/sjamf.sjamf_74_19

Cited by 8 publications

(6 citation statements)

References 2 publications

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“…Among the total studies included, 8 were conducted in eastern Africa, 12–18,19 4 in West Africa, 20,21,22–24 15 in northern Africa, 25–38,39 , and 1 in Southern Africa. 40 Twenty-four studies were conducted in referral hospitals, 12–18,19,22–24,26,27,29–33,35–40 two in general hospitals, 22,23 and five in cardiac centers 20,21,25,28,34 (Table 1).…”

Section: Resultsmentioning

confidence: 99%

“…Among the total studies included, 8 were conducted in eastern Africa, [12][13][14][15][16][17][18]19 4 in West Africa, 20,21,[22][23][24] 15 in northern Africa, [25][26][27][28][29][30][31][32][33][34][35][36][37][38]39 , and 1 in Southern Africa. 40 Twenty-four studies were conducted in referral hospitals, [12][13][14][15][16][17][18]19,[22][23][24]26,27,[29][30][31][32][33][35][36][37][38]…”

Section: Characteristics Of Included Studiesmentioning

confidence: 99%

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In-hospital mortality from acute coronary syndrome in Africa: a systematic review and meta-analysis

et al. 2023

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Objective: There is an increasing recognition of the burden of cardiovascular disease in Africa. However, little is known about the pooled prevalence of acute coronary syndrome (ACS)-associated in-hospital mortality and contributing factors. Methods: PubMed, Medline, Embase, Web of Science (Core Collection), and supplementary sources including Google Scholar, World Cat, Research Gate, and Cochrane Library were searched. Chi-square test and I2-statistic were used to assess heterogeneity. Egger’s and Begg’s tests and funnel plots were used to assess publication bias. Data were analyzed using Stata software (version 15.0). Result: Twenty nine studies with a total sample of 11,788 were included. The pooled estimate of all-cause in-hospital mortality was 22% (pooled proportion (PP) = 0.22; 95% confidence interval (CI): 0.17–0.27. The In-hospital mortality rate was lower at the cardiac centers (PP = 0.14; CI: 0.05–0.23) compared to referral hospitals (PP = 0.24; CI: 0.17–0.31]) The mortality rate was comparable in Eastern (PP = 0.23; CI: 0.19–0.27) and Northern Africa (PP = 0.22; CI: 0.16–0.28). The incidence of in-hospital heart failure, cardiogenic shock, arrhythmia, bleeding, acute stroke, and reinfarction were 42, 17.0, 20.0, 16.0, 4.0, and 5.0%, respectively. Conclusion: All-cause in-hospital mortality rate associated with ACS is high in Africa. The mortality rate at cardiac centers was 10% lower when compared with referral hospitals. Establishing coronary units, strengthening existing cardiac services, and improving availability and access to cardiovascular medicines could help in reducing the burden of ACS in the continent.

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Section: Resultsmentioning

confidence: 99%

Section: Characteristics Of Included Studiesmentioning

confidence: 99%

In-hospital mortality from acute coronary syndrome in Africa: a systematic review and meta-analysis

et al. 2023

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“…Questionnaire: An Arabic questionnaire was developed by the researchers, after reviewing the related literature and research studies (3,22,23) . It included the following parts: literatures (24) .…”

Section: A-patient Structured Interviewmentioning

confidence: 99%

“…While, CAD is a significant cause of death and disability, it is preventable (1,2) . (Anxiety and stress) (2,3) .…”

Section: Introductionmentioning

confidence: 99%

Effectiveness of Educational Guidelines Adherence on Health Complaints and Anxiety Level among Patients with Coronary Artery Disease

Srour

Ali

2021

Tanta Scientific Nursing Journal

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Coronary artery disease is the leading cause of death globally and the most common type of heart disease. Health complaints are subjective in nature; it may afford information on the degree of recovery from coronary artery disease. Educational guidelines play a vital role in increasing knowledge, practice, and modifying health behaviors. This study aimed to evaluate the effect of educational guideline adherence on health complaints and anxiety level among patients with coronary artery disease. Subjects and Method: Design: Quasi-experimental research design. Setting: The study was conducted at cardiology and coronary care unit affiliated with El Hussein University Hospitals. Subjects: A Purposive sample of 104 adult patients was selected and equally divided into (52) study and (52) control group. Three Tools include Patients' Structured Interview Questionnaire, The Somatic Health Complaints Questionnaire and Beck Anxiety Inventory Questionnaire was used in this study. Results: The mean age of the study and control group were (54.21±8.01& 54.71 ±10.42, respectively), 59.6% of both groups were males. There was a highly statistically significant difference between study and control group regarding total mean scores of knowledge, all dimensions of health complaints and anxiety level scores (p > 0.001) at post and follows up phases throughout implementation. Conclusion: There was a highly statistically significant improvement regarding the mean scores of total knowledge, somatic health complaints and anxiety level for the study group at the post and follow up phases of the educational guidelines Adherence implementation.Recommendation: Develop Telecommunication interventions in secondary prevention for patients with CAD to promote effective reduction of risk factors.

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“…Acute coronary syndrome (ACS) is one of the atherosclerotic cardiovascular diseases (ASCVD) that is the leading cause of death worldwide, accounting for 37% of all deaths in people under the age of 70 [1]. ACS is the first clinical manifestation of coronary artery disease (CAD) and defined as the partial or complete occlusion of one of the coronary arteries, which results in partial or complete deficiency in blood supply to the myocardium [2].…”

Section: Introductionmentioning

confidence: 99%

Efficacy and Safety of Atorvastatin 40 mg versus Rosuvastatin 20 mg in Patients with Type 2 Diabetes Mellitus and Previous Acute Coronary Syndrome: A Randomized Clinical Trial

Ebid

Genina

Al-Jendy

et al. 2022

Clinical Diabetology

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Background: The purpose of this study was to compare the efficacy and safety of high-dose atorvastatin (40 mg) versus high-dose rosuvastatin (20 mg) in Egyptian patients with type 2 diabetes and previous acute coronary syndrome history. Materials and methods: This open-labeled prospective, randomized clinical trial compared once daily atorvastatin 40 mg (Ator ® ) versus once daily rosuvastatin 20 mg (Crestor ® ). The primary outcome was the 50% reduction in low-density lipoprotein cholesterol levels at 12 weeks. The secondary outcome was the achievement of low-density lipoprotein cholesterol level < 55 mg/dL. Results: A total number of 108 patients had a significant percentage of improvement in atorvastatin arm (n = 59) and rosuvastatin arm (n = 49) in low-density lipoprotein cholesterol, total cholesterol, triglycerides, and high-density lipoprotein-cholesterol achieved (p ≤ 0.05). In atorvastatin arm, 32.2% of patients achieved fifty percent reduction in low-density lipoprotein cholesterol while 34.7% of patients in rosuvastatin arm (p > 0.05). Twenty percent of patients achieved low-density lipoprotein cholesterol < 55 mg/dL in atorvastatin group compared to eighteen percent only in rosuvastatin group (p > 0.05). Regarding safety, the mean difference in liver transaminases was non-significant between the two groups (p > 0.05). Muscular symptoms were experienced by 1.7% patients receiving atorvastatin 40 mg and 10.2% of those receiving rosuvastatin 20 mg (p > 0.05). Conclusions: In Egyptian context, both high doses statin therapy were comparable regarding efficacy and safety in patients with type 2 diabetes and previous history of acute coronary syndrome. The Clinicaltrial.gov registration ID is: NCT05306990.

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Epidemiological and clinical profile of acute coronary syndrome of Egyptian patients admitted to the Coronary Care Unit, Al-Azhar University Hospital, New Damietta

Cited by 8 publications

References 2 publications

In-hospital mortality from acute coronary syndrome in Africa: a systematic review and meta-analysis

In-hospital mortality from acute coronary syndrome in Africa: a systematic review and meta-analysis

Effectiveness of Educational Guidelines Adherence on Health Complaints and Anxiety Level among Patients with Coronary Artery Disease

Efficacy and Safety of Atorvastatin 40 mg versus Rosuvastatin 20 mg in Patients with Type 2 Diabetes Mellitus and Previous Acute Coronary Syndrome: A Randomized Clinical Trial

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