Epidemiological and structural studies of Staphylococcus aureus R plasmids mediating resistance to tobramycin and streptogramin

Solh, Névine El; Fouace, J; Z, Shalita; Bouanchaud, D. H.; Novick, Richard P.; Chabbert, Y

doi:10.1016/0147-619x(80)90087-6

Cited by 42 publications

(25 citation statements)

References 4 publications

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“…wt plasmid (Lacey, 1975 and1984) such as that detected in our phenotype-I MGRSA strains and in some American and Australian isolates (McDonnell et al, 1983;Gillespie et al, 1984). Resistance to tetracycline specified by large plasmids such as those found in our phenotype-I1 strains have been reported previously in S. aureus in strains from France that were also resistant to streptogramin B antibiotics (El Solh et al, 1980).…”

Section: Discussionmentioning

confidence: 87%

Susceptibility to Antimicrobial Agents and Analysis of Plasmids in Gentamicin- And Methicillin-Resistant Staphylococcus Aureus From Dublin Hospitals

Coleman

Pomeroy

Estridge

et al. 1985

Journal of Medical Microbiology

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Section: Discussionmentioning

confidence: 87%

Susceptibility to Antimicrobial Agents and Analysis of Plasmids in Gentamicin- And Methicillin-Resistant Staphylococcus Aureus From Dublin Hospitals

Coleman

Pomeroy

Estridge

et al. 1985

Journal of Medical Microbiology

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“…Plasmid pIP1630 contained two PstI-PvuII fragments of 1.3 kb (Fig. 3) The restriction profiles of pIP1629 and pIP1630 were compared with those of the staphylococcal plasmids conferring resistance to pristinamycin described to date (18,23). No common restriction fragments were detected (data not shown).…”

Section: Resultsmentioning

confidence: 99%

“…In France, resistance to pristinamycin was first encountered among staphylococci in 1975 (4,12,17,18). To date, the prevalence of such strains remains low (<2%) (16,23 nants are occasionally associated with the presence of plasmids in transconjugants.…”

mentioning

confidence: 99%

Analysis of pristinamycin-resistant Staphylococcus epidermidis isolates responsible for an outbreak in a Parisian hospital

Loncle

Casetta

Buu-Hoï

et al. 1993

Antimicrob Agents Chemother

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In 1990, over a 6-month period, an increase from 1 to 10%Y in the incidence of pristinamycin resistance among coagulase-negative staphylococci was observed in four intensive care units of a Parisian hospital.Twenty-three such isolates, as well as 25 pristinamycin-susceptible Staphylococcus epidermidis isolates, were collected and typed by analyzing various bacterial constituents. Two structurally related plasmids of 7.3 and 14.3 kb, carrying the gene vga encoding resistance to pristinamycin, were detected in the 23 pristinamycinresistant coagulase-negative staphylococci which were identified as S. epidermidis. Although related by numerous common characteristics, 20 of these 23 isolates could be divided into two types, A (17 isolates) and B (three isolates). These types were characterized on the basis of their plasmid contents and hybridization patterns obtained when the EcoRI-digested DNA was probed with plasmid pIP1551 containing an internal fragment of the insertion sequence IS256. These findings suggest that the dissemination of type A epidemic strains was, in large part, responsible for the outbreaL

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“…The value of plasmid analysis in the epidemiological study of nosocomial infection with S. aureus is well established (McGowan et al, 1979;El Solh et al, 1980;Locksley et a/., 1982). We have examined previously strains of antibiotic multiresistant S. aureus, isolated from patients in Melbourne hospitals, for the presence of resistance plasmids (Lyon et al, 1982;Lyon, May and Skurray, 1983).…”

Section: Introductionmentioning

confidence: 99%

Molecular epidemiology of multiresistant Staphylococcus aureus in Australian hospitals

Lyon

Iuorio

May

et al. 1984

Journal of Medical Microbiology

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Mic r o b iology Depart men t , Monas h Un iversi ty , Clayton, Vie t o r ia , A us t ral ia , 3 I68SUMMARY. Antibiotic multiresistant isolates of Staphylococcus aureus from outbreaks of nosocomial infection throughout Australia were found to possess essentially similar patterns of antibiotic resistance. Plasmid DNA profiles from these isolates exhibited a common pattern of large plasmids, of ( I 5-22) x lo6 mol. wt, associated with resistance to gentamicin, kanamycin and tobramycin, plasmids of 3 x lo6 mol. wt, mediating resistance to chloramphenicol, and cryptic plasmids of 1 x lo6 mol. wt. Restriction endonuclease digestion confirmed the presence of related plasmids in isolates from all the hospitals that were surveyed. The homogeneity of these organisms suggests the dissemination of a multiresistant, plasmid-bearing strain of S. aureus, or its derivatives, among geographically-separated hospitals in Australia.

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Epidemiological and structural studies of Staphylococcus aureus R plasmids mediating resistance to tobramycin and streptogramin

Cited by 42 publications

References 4 publications

Susceptibility to Antimicrobial Agents and Analysis of Plasmids in Gentamicin- And Methicillin-Resistant Staphylococcus Aureus From Dublin Hospitals

Susceptibility to Antimicrobial Agents and Analysis of Plasmids in Gentamicin- And Methicillin-Resistant Staphylococcus Aureus From Dublin Hospitals

Analysis of pristinamycin-resistant Staphylococcus epidermidis isolates responsible for an outbreak in a Parisian hospital

Molecular epidemiology of multiresistant Staphylococcus aureus in Australian hospitals

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