Epidemiological and survival analysis of early and middle stage femoral head necrosis

Abstract

Objective: To investigate the venereal characteristics and survival time of osteonecrosis of femoral head (ONFH).Methods: 970 patients with early and mid-term ONFH in our hospital from 1998 to 2014 were selected for epidemiological study. The general and clinical data of patients, including age, gender, etiology, alcohol intake, hormone use, body mass index and femoral head survival years, were collected by telephone, outpatient recurrence and other methods for statistics and analysis.Results: among 970 patients, there were 694 males and 276 females, with an average age of 40.87 ± 10.42 years. The average age of onset in women is younger than that in men. Male patients have a high incidence of alcoholic ONFH and female patients have a high incidence of hormonal ONFH. There was no significant difference in the duration of hormone use between hormone and alcohol combined necrosis and hormone induced ONFH, but the onset time was significantly shortened. The drinking history of female mixed bad death was higher than that of male, and the amount of alcohol consumed in a single week was greater than that of pure alcohol bad death, but the drinking years showed a downward trend. The survival time of people over 50 years old is higher than that of other age groups. The survival time of alcoholic necrosis is significantly longer than that of the other three types of necrosis, and the worst survival time is hormone necrosis. The analysis of disease stage survival showed that the lower the classification, the better the prognosis, and vice versa. Low weight patients have a longer survival time in the femoral head, while overweight people have a shorter survival time.Conclusion: this epidemiological study of early and medium-term femoral head necrosis has refined the intake characteristics of hormone and alcohol factors, analyzed the distribution characteristics of the disease, and made a detailed survival analysis of the femoral head, laying a solid foundation for further research.