Epidemiological aspects of Budd-Chiari in Egyptian patients: A single-center study

Abstract

FVLM is the most common disease etiology and MTHFR the second most common in Egyptian BCS patients. BCS etiology tends to vary with geographic region.

Budd-Chiari syndrome due to giant hydatid cyst: a case report and brief literature review

“…The exact prevalence of BCS is unknown, but it has been estimated to affect 1/100,000 individuals in the general population worldwide, with a higher prevalence occurring in developing countries [5,7]. BCS affects individuals of all racial groups, usually during the third or fourth decade of life.…”

“…Occlusion may occur at the level of the hepatic veins or the IVC at any point between the entrance to the hepatic veins and the right atrium [4]. The etiology of BCS can be classified as primary, attributable to intrinsic intraluminal thrombosis or the development of venous webs; or secondary, caused by intraluminal invasion by a parasite or malignant tumor or extraluminal compression by an abscess, solid tumor, or cyst, such as a hydatid cyst [5]. In this study, we present the case of a patient with a giant hydatid cyst manifesting with BCS symptoms and signs caused by compression of the IVC and hepatic veins.…”

Behçet's disease in Budd-Chiari Syndrome

“…In the current study, we compared the course of the disease in 14 patients with BCS and BD to a cohort of patients with BCS in whom BD was excluded as the underlying cause. Previous surveys indicate that BD may be responsible for up to 13% of the cases of BCS [1][2][3].…”

Budd-Chiari Syndrome in a Patient with JAK2V617F and Factor V G1691A Mutations

“…In the current classification of MPN by the World Health Organization, it is recommended to test for the presence of JAK-2 V617F somatic mutation (4), which is present in 40 to 60% of patients with BCS (5). Furthermore, patients with MPN who are found to be positive for the JAK-2 V617F mutation usually have a poor clinical progression of the disease, in part due to an increase in the development of multiple forms of thrombosis (6).…”

“…According to a recent investigation, Factor V Leiden mutation was found in 53.1% of 64 patients with BCS, representing the most common prothrombotic disorder associated with the disorder, followed by the mutation in the gene of the metilentetrahidrofolate reductase (6).…”