Epidemiological Aspects of Sepsis

Abstract

Last decades a sepsis problem attracts the increased interest in the world community. In spite of definite achievements of modern fundamental and clinical medicine, sepsis as before is characterized by significant dissemination and high lethality. The problems of sepsis spread in various countries are discussed. It is shown that annually million cases of generalized purulent-septic infections are diagnosed. Steady sepsis increase is registered in industrially developed countries. Share of severe sepsis in pathology structure varies from 2 to 43% in different territories. Sepsis still remains among leading causes of human death being characterized by essential hospital lethality (from 30,6 to 80,4%). The patient categories belonging to high risk groups of sepsis development are shown. Special attention is directed to epidemiological manifestations of this pathological syndrome in pediatrics. Features of etiologic spectrum of the sepsis causative agents, increasing etiological importance of multi-resistant bacteria (Pseudomonas aeruginosa, Klebsiella pneumoniae, Acinetobacter spp., MRSA, VRE, etc.) are demonstrated. In consideration of clinical-epidemiological, social and economic significance of sepsis, studying of its epidemiological aspects is the major direction of activities for Public Health services.

A new look inside planetary nebula LoTr 5: a long-period binary with hints of a possible third component

“…Photometric variability in HD 112313 was firstly found by Schnell & Purgathofer (1983), who reported four different periods between 0.35 and 1.2 days, although they stated that the 1.2-day period was the most probable. Later on, Noskova (1989) detected the 5.9 days period, which was independently found by H. E. Bond in 1988 (see Bond & Livio 1990). This 5.9 days period was also confirmed in the subsequent years by Kuczawska & Mikolajewski (1993), Jasniewicz et al (1996), and Strassmeier et al (1997), who interpret this period as the rotational period of the G-type star and the 1.2 days period as an alias of the true period.…”

Microbiological Monitoring in the System of Epidemiological Surveillance of Purulent-Septic Infections in a Multidisciplinary Hospital

“…Многие зарубежные авторы также указывают на преимущественное влияние грамотрицательной флоры на тяжесть течения и летальность от сепсиса. Вместе с тем, в настоящее время отсутствуют доказательные данные о превалировании той или иной группы бактерий, но отмечаются их существенные различия в структуре внебольничного и нозокомиального сепсиса [10,11,12,13]. Изучение структуры и динамики антибиотикорезистентности микроорганизмов, выделяемых от септических больных, является важной задачей для определения адекватной антибактериальной терапии [14].…”