Epidemiological characteristics and transmission dynamics of the outbreak caused by the SARS-CoV-2 Omicron variant in Shanghai, China: A descriptive study

Infection of healthcare workers despite a high vaccination rate during the fifth wave of COVID-19 due to Omicron variant in Hong Kong

“…The emergence of Omicron sublineages (BA.1, BA.2, to BA.4 and BA.5) of increasing transmissibility [ 11 ] has resulted in explosive outbreaks in the community [ [12] , [13] , [14] , [15] ]. Models simulating the household setting underscored the contribution of airborne transmission of the Omicron variant, especially during asymptomatic or pre-symptomatic infection, as compared with the ancestral strain [ 16 ].…”

The Omicron BA.2.2.1 subvariant drove the wave of SARS-CoV-2 outbreak in Shanghai during spring 2022

“…Recently, between late February and early July 2022, the city of Shanghai was hit by a wave of SARS-CoV-2 infections, leading to a total of almost 650,000 laboratory-confirmed cases of COVID-19 and 595 deaths (crude case fatality rate: 0.092%) 4 , 5 . To identify the SARS-CoV-2 variant(s) causing this outbreak, we used whole-genome targeted sequencing technology to obtain 253 high-quality SARS-CoV-2 genome assemblies from COVID-19 patients diagnosed during the early-to-mid stages of the outbreak (Fig.…”

Performance evaluation of antigen detection rapid diagnostic test (Ag-RDT) for COVID-19 diagnosis in a primary healthcare center during the Shanghai COVID-19 quarantine period

“…Since SARS-CoV-2 culture and sequencing were not performed in the current study, the exact sensitivity of the current Ag-RDTs remained inconclusive for different SARS-CoV-2 variants. According to the literature, the Omicron was the major viral strain during the study period [ 21 , 22 ]. Thus, we believe that the results of the current study mainly reflected the performance of Ag-RDT targeting the Omicron.…”