2004
DOI: 10.1038/sj.jhh.1001702
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Epidemiological, pathophysiological and clinical significance of systolic, diastolic and pulse pressure

Abstract: Long-term population surveys and studies of untreated hypertensive patients both strongly suggest that over the age of about 45, the height of the systolic blood pressure is a better predictor of cardiovascular outcome than the diastolic pressure. Research into echocardiographic left ventricular size, endothelial function and thromborheology also back up this supposition. In clinical practice, the treatment of isolated systolic hypertension has been shown to be very worthwhile. There remains some uncertainty a… Show more

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Cited by 30 publications
(19 citation statements)
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“…We chose SBP as the outcome measure because it is a stronger predictor of cardiovascular risk and leads to more accurate diagnosis and staging of hypertension than diastolic BP [16,17]. It has been suggested as the primary target of antihypertensive treatment [18].…”
Section: Study Variablesmentioning
confidence: 99%
“…We chose SBP as the outcome measure because it is a stronger predictor of cardiovascular risk and leads to more accurate diagnosis and staging of hypertension than diastolic BP [16,17]. It has been suggested as the primary target of antihypertensive treatment [18].…”
Section: Study Variablesmentioning
confidence: 99%
“…Many studies, however, emphasized the importance and benefits of treating diastolic hypertension in young adults (7,(13)(14)(15)(16)(17). It has been recommended by many authors that IDH should be monitored and affected persons should be managed targeting the control of all cardiovascular risk factors (18). Previous surveys in KSA reported a 5.3% prevalence of IDH more than two decades ago (4).…”
mentioning
confidence: 99%
“…• Above the ages of 45-50 years, which is the mean age of this population, systolic pressure becomes progressively more important as a predictor of cardiovascular events [18]. • In most populations systolic blood pressure rises steadily with age, while diastolic pressure reaches a plateau or declines [19].…”
Section: Differential Effects On Systolic and Diastolic Blood Pressurementioning
confidence: 99%