Epidemiological profile and genetic diversity of sapoviruses (SaVs) identified in children suffering from acute gastroenteritis in Pune, Maharashtra, Western India, 2007–2011

Lasure, Neha; Gopalkrishna, Varanasi

doi:10.1017/s0950268816001953

Cited by 18 publications

(23 citation statements)

References 35 publications

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“…Since the study hospital was the paediatric referral centre for more than 500 000 people of all ages, the results are likely to have reflected the situation at a national level. The percentages of sapoviruses from the last four seasons were in line with other studies conducted in India, the Philippines and South Africa, which showed that the sapovirus represented 2.7-7.7% of acute gastroenteritis in hospitalised children (6,26,27). A six-year surveillance study conducted in Nara, Japan, showed sapoviruses in 2.1-11.3% of cases of acute gastroenteritis, with GI.1 as the predominant strain (28).…”

Section: Discussionsupporting

confidence: 88%

“…In a prospective community‐based study conducted in Finland in the 1990s, sapoviruses were present in 9% of all episodes of acute gastroenteritis in children . Studies carried out elsewhere found that sapoviruses were detected in 2.7% to 15.4% of acute gastroenteritis episodes of hospitalised children and from 3.7% to 19.2% of acute gastroenteritis in outpatients of all ages . The rotavirus vaccination was introduced into Finland as part of the National Immunisation Programme in 2009 and was followed by a drastic decline in the rotavirus.…”

Section: Introductionmentioning

confidence: 99%

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The role of the sapovirus infection increased in gastroenteritis after national immunisation was introduced

2019

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Aim This study examined the prevalence and clinical significance of the sapovirus infection in children with acute gastroenteritis before and after the introduction of the rotavirus vaccination in Finland in 2009. Methods We collected 1437 stool samples from children under 16 years during three prospective hospital‐based surveillance studies of acute gastroenteritis at Tampere University Hospital, Finland. The children were seen in the emergency department (47%) or admitted to the ward (53%). Sapovirus findings from 2006 to 2008 (n = 759), before national immunisation, were compared to 2009–2011 (n = 330) and 2012–2014 (n = 348), after the national programme was launched. Results The overall incidence of the sapovirus was 3.3%. It was present in 1.4% of acute gastroenteritis cases in 2006–2008 and 5.5% in the post‐vaccination years, but the absolute number did not increase. Sapoviruses mainly occurred in the winter and spring, but did not follow the prevalence of the norovirus or rotavirus. Sapovirus GI.1 and GII.1 were the most common genotypes, but the predominant strain was different each season. Many sapovirus lineages appeared during multiple seasons and reappeared later. Conclusion The sapovirus was uncommonly and sporadically detected in children seen in the hospital for acute gastroenteritis, and its relative role increased after national immunisation was introduced.

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Section: Discussionsupporting

confidence: 88%

Section: Introductionmentioning

confidence: 99%

The role of the sapovirus infection increased in gastroenteritis after national immunisation was introduced

2019

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“…In India, SaV was detected at the rate of 2.7% (21 of 778) for symptomatic patients and 1.9% (4 of 207) for asymptomatic control group from 2007 to 2011. 34 In Thailand, only six (0.7%) samples were detected SaV-positive out of 889 fecal specimens from 2012 to 2014. 23 However, high rates of SaV infections more than 10% were reported in Latin America and Spain.…”

Section: Discussionmentioning

confidence: 94%

“…Globally, the low detection rate of SaV has also been reported in many countries. In India, SaV was detected at the rate of 2.7% (21 of 778) for symptomatic patients and 1.9% (4 of 207) for asymptomatic control group from 2007 to 2011 . In Thailand, only six (0.7%) samples were detected SaV‐positive out of 889 fecal specimens from 2012 to 2014 .…”

Section: Discussionmentioning

confidence: 99%

Prevalence and genetic diversity of human sapovirus associated with sporadic acute gastroenteritis in South China from 2013 to 2017

Xue¹,

Cai²,

Zhang³

et al. 2019

Journal of Medical Virology

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Human sapovirus (SaV) is an important viral agent for acute diarrhea worldwide, but timely prevalence data of human SaV in South China are still lacking. In this study, a 4‐year surveillance was conducted to characterize the prevalence and genetic characteristics of the circulating SaV associated with sporadic diarrhea in South China. From November 2013 to October 2017, 569 fecal samples from patients with acute diarrhea were collected. SaV was detected in 11 samples with a positive rate of 1.93%. Three human genogroups of GI, GII, and GIV were identified, including five GI.1 strains, three GI.2 strains, one GI.3 strain, one GII.8 strain, and one GIV strain. Furthermore, multiple alignments of complete capsid protein VP1 genes of five local GI.1 strains and other available GI.1 strains in GenBank were performed. Average pairwise identities were calculated at 95.33% and 99.36% at nucleotide and amino acid levels, and only six variable amino acid sites were found during its 36‐years’ evolution process. GI.1 strains could be further phylogenetically divided into four clusters with an approximate temporal evolution pattern, and local strains belonged to Cluster‐d with other four strains from China and Japan. In summary, SaV was identified as an etiological agent responsible for sporadic gastroenteritis in Guangzhou with a low prevalence rate as in other Chinese cities, but its high genetic diversity suggested the necessity of continuous SaV surveillance in the future.

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“…Among these, SaV GI and GII are the most prevalent genogroups detected worldwide while other genogroups have been rarely detected (Magwalivha et al, 2018). Like noroviruses, several SaV recombinant strains of both intragenogroup and intergenogroup recombinations have been reported (Chanit et al, 2009;Lasure & Gopalkrishna, 2017;Liu et al, 2015). Within SaV genome, recombination generally occurs in the ORF1, particularly at the junction between the polymerase (NS7) and capsid (VP1) genes (Hansman et al, 2005;Katayama et al, 2004;Phan et al, 2006).…”

Section: Introductionmentioning

confidence: 99%

Genetic recombination and diversity of sapovirus in pediatric patients with acute gastroenteritis in Thailand, 2010–2018

Khamrin

Ushijima

Chen

et al. 2020

PeerJ

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Background Human sapovirus (SaV) is an etiologic agent of acute gastroenteritis (AGE) in all age groups worldwide. Genetic recombination of SaV has been reported from many countries. So far, none of SaV recombinant strain has been reported from Thailand. This study examined the genetic recombination and genotype diversity of SaV in children hospitalized with AGE in Chiang Mai, Thailand. Methods Stool samples were collected from children suffering from diarrhea who admitted to the hospitals in Chiang Mai, Thailand between 2010 and 2018. SaV was detected by RT-PCR and the polymerase and capsid gene sequences were analysed. Results From a total of 3,057 samples tested, 50 (1.6%) were positive for SaV. Among positive samples, SaV genotype GI.1 was the most predominant genotype (40%; 20/50), followed by GII.1 and GII.5 (each of 16%; 8/50), GI.2 (14%; 7/50), GIV.1 (4%; 2/50), and GI.5 (2%; 1/50). In addition, 4 SaV recombinant strains of GII.1/GII.4 were identified in this study (8%; 4/50). Conclusions The data revealed the genetic diversity of SaV circulating in children with AGE in Chiang Mai, Thailand during 2010 to 2018 and the intragenogroup SaV recombinant strains were reported for the first time in Thailand.

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Epidemiological profile and genetic diversity of sapoviruses (SaVs) identified in children suffering from acute gastroenteritis in Pune, Maharashtra, Western India, 2007–2011

Cited by 18 publications

References 35 publications

The role of the sapovirus infection increased in gastroenteritis after national immunisation was introduced

The role of the sapovirus infection increased in gastroenteritis after national immunisation was introduced

Prevalence and genetic diversity of human sapovirus associated with sporadic acute gastroenteritis in South China from 2013 to 2017

Genetic recombination and diversity of sapovirus in pediatric patients with acute gastroenteritis in Thailand, 2010–2018

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