Epidemiological research priorities for public health control of the ongoing global novel coronavirus (2019-nCoV) outbreak

Cowling, Benjamin J.; Leung, Gabriel M.

doi:10.2807/1560-7917.es.2020.25.6.2000110

Cited by 149 publications

(140 citation statements)

References 22 publications

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“…China must now focus on adjusting tactics and strategies as new evidence becomes available. 3,6 Much remains to be done and many questions remain unanswered. China is very grateful for the help it is receiving from the international scientific, health, and public health communities.…”

Section: Response To the Covid-19 Epidemicmentioning

confidence: 99%

Characteristics of and Important Lessons From the Coronavirus Disease 2019 (COVID-19) Outbreak in China

McGoogan

2020

JAMA

15,629

209

6,587

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Section: Response To the Covid-19 Epidemicmentioning

confidence: 99%

Characteristics of and Important Lessons From the Coronavirus Disease 2019 (COVID-19) Outbreak in China

McGoogan

2020

JAMA

15,629

209

6,587

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“…We estimate the distribution of serial intervals for 468 confirmed cases of reported in 93 Chinese cities by February 8, 2020. Keywords: Wuhan, coronavirus, epidemiology, serial interval A new coronavirus (COVID-19) emerged in Wuhan, China in late 2019 and was declared a public health emergency of international concern by the World Health Organization (WHO) on January 30, 2020 (1) . As of February 19, 2020, the WHO has reported over 75,204 COVID-19 infections and over 2,009 COVID-19 deaths (2) , while key aspects of the transmission dynamics of COVID-19 remain unclear (3) . The serial interval of COVID-19 is defined as the time duration between a primary case (infector) developing symptoms and secondary case (infectee) developing symptoms (4,5) .…”

Section: One Sentence Summarymentioning

confidence: 99%

The serial interval of COVID-19 from publicly reported confirmed cases

et al. 2020

Preprint

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As a novel coronavirus continues to emerge throughout China and threaten the globe, its transmission characteristics remain uncertain. Here, we analyze the serial . CC-BY-NC-ND 4.0 International license It is made available under a is the author/funder, who has granted medRxiv a license to display the preprint in perpetuity. (which was not peer-reviewed)The copyright holder for this preprint . https://doi.org/10. 1101 intervals-the time period between the onset of symptoms in an index (infector) case and the onset of symptoms in a secondary (infectee) case-of 468 infector-infectee pairs with confirmed COVID-19 cases reported by health departments in 18 Chinese provinces between January 21, 2020, and February 8, 2020. The reported serial intervals range from -11 days to 20 days, with a mean of 3.96 days (95% confidence interval: 3.53-4.39), a standard deviation of 4.75 days (95% confidence interval: 4.46-5.07), and 12.1% of reports indicating pre-symptomatic transmission.

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“…The dominant mode of transmission is from the respiratory tract via droplets or indirectly via fomites, and to a lesser extent via aerosols. In addition, as SARS-CoV and MERS-CoV can infect the human gastrointestinal tract 21,22 , it has been suggested that faecal-oral spread may occur for SARS-CoV-2 23 . The reproduction number (Ro) is generally thought to be between 2.0 and 2.8 20,24-27 , although higher reproduction numbers have been suggested in some reports.…”

mentioning

confidence: 99%

COVID-19: a novel zoonotic disease caused by a coronavirus from China: what we know and what we don't

Mackenzie¹,

2020

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At the end of December, 2019, a new disease of unknown aetiology appeared in Wuhan, China. It was quickly identified as a novel betacoronavirus, and related to SARS-CoV and a number of other bat-borne SARS-like coronaviruses. The virus rapidly spread to all provinces in China, as well as a number of countries overseas, and was declared a Public Health Emergency of International Concern by the Director-General of the World Health Organization on 30 January 2020. This paper describes the evolution of the outbreak, and the known properties of the novel virus, SARS-CoV-2 and the clinical disease it causes, COVID-19, and comments on some of the important gaps in our knowledge of the virus and the disease it causes. The virus is the third zoonotic coronavirus, after SARS-CoV and MERS-CoV, but appears to be the only one with pandemic potential.

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Epidemiological research priorities for public health control of the ongoing global novel coronavirus (2019-nCoV) outbreak

Cited by 149 publications

References 22 publications

Characteristics of and Important Lessons From the Coronavirus Disease 2019 (COVID-19) Outbreak in China

Characteristics of and Important Lessons From the Coronavirus Disease 2019 (COVID-19) Outbreak in China

The serial interval of COVID-19 from publicly reported confirmed cases

COVID-19: a novel zoonotic disease caused by a coronavirus from China: what we know and what we don't

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