Epidemiological Surveillance of Norovirus Diarrhea in Hospitalized Children with Acute Gastroenteritis in South of Iran

Najafi, Akram; Iranpour, D; Najafi, Shariat

doi:10.5812/jjm.7866

Cited by 4 publications

(4 citation statements)

References 19 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The most commonly associated clinical symptom observed in this study with rotavirus, adenovirus, and norovirus positive cases was “vomiting” with 55.6%, 55.8%, and 75.0%, respectively. This finding is similar to other studies [ 23 – 25 ] where vomiting was the most commonly associated symptom with viral diarrhea. Rotavirus positive patients with respect to clinical symptoms such as fever, dehydration, and abdominal pain were low in this study compared to other studies [ 23 , 26 , 27 ] which reported high percentage of clinical symptoms.…”

Section: Resultssupporting

confidence: 92%

“…Similarly, for adenovirus positive patients, fever, dehydration, and abdominal pain were low compared to other studies with moderate symptoms [ 13 , 24 , 28 , 29 ]. However, as regards norovirus positive patients, fever, dehydration, and abdominal pain were also low, but other studies with norovirus showed moderate to high clinical symptoms [ 25 , 30 , 31 ]. Thus, the differences in clinical symptoms with viral diarrhea as seen from the different studies may be attributed to seasonal variations, geographical location, nutritional status of the patients, and type of viral pathogens causing the infection.…”

Section: Resultsmentioning

confidence: 95%

See 1 more Smart Citation

Viral Agents of Diarrhea in Young Children in Two Primary Health Centers in Edo State, Nigeria

Imade

Eghafona

2015

International Journal of Microbiology

View full text Add to dashboard Cite

Enteric viruses have been shown to be responsible for diarrhea among children during their early childhood. This study was carried out to determine the prevalence of rotavirus, adenovirus, and norovirus infection in young children with diarrhea in two primary health centers in Edo State, Nigeria. A total of 223 stool specimens were collected from children aged 0–36 months with clinical signs of diarrhea and 59 apparently healthy age-matched children as control. These specimens were investigated for three viral agents using immunochromatographic technique (ICT). The overall results showed that at least one viral agent was detected in 95/223 (42.6%) of the children with diarrhea while the control had none. The prevalence of rotavirus was 28.3%, adenovirus 19.3%, and norovirus 3.6%. There was a significant association between age group and infection (P < 0.0001). Seasonal pattern of enteric viruses was not statistically significant (P = 0.17). The overall coinfection rate was 7.6% and rotavirus-adenovirus coinfection had the highest with 5.4%. Rotavirus was the most prevalent viral agent. Coinfections are not uncommon among the population studied. The most commonly associated clinical symptom of viral diarrhea in this study was vomiting. Viral diagnostic tests are advocated for primary health care facilities in this locality.

show abstract

Section: Resultssupporting

confidence: 92%

Section: Resultsmentioning

confidence: 95%

Viral Agents of Diarrhea in Young Children in Two Primary Health Centers in Edo State, Nigeria

Imade

Eghafona

2015

International Journal of Microbiology

View full text Add to dashboard Cite

show abstract

“…In the report, most commonly reported symptoms were diarrhea, fever, vomiting, abdominal pain in virus-infected patients. These findings are in accordance with those conducted in South of Iran, Venezuela, Spain, Hungary and in Brasil were found fever and lymphocytosis to be significantly higher in adenovirus-rotavirus co-infected patients (40,41) Clinically, it would be difficult to separate viral gastroenteritis from gastroenteritis caused by other microorganism particularly, bacterial gastroenteritis. Molecular methods raised the overall diagnostic efficacy by 10%, and by 2.5% each for adenovirus and rotavirus (10).…”

Section: Discussionsupporting

confidence: 90%

Low Endemic Frequency of Adenovirus, Rotavirus and Norovirus in Pediatric Diarrhea Samples from Central Iran

Abbasi

Mondanizadeh

Belkum³

et al. 2020

Preprint

View full text Add to dashboard Cite

Background: Acute viral gastroenteritis is a disorder that affects children on a worldwide scale but mostly in developing countries. Adenoviruses, rotaviruses, and noroviruses are the major viral cause of childhood gastroenteritis. This study is the first to investigate the prevalence of these viruses in diarrhea samples from pediatric patients living in central Iran.Methods: A total of 173 samples of pediatric diarrhea, from May 2015 to May 2016, was included in this descriptive cross-sectional study. The samples were analyzed using in-house developed PCR and reverse transcription (RT) -PCR methods to investigate the prevalence of adeno-, rota- and noroviruses. Results: Out of 173 samples of pediatric diarrhea, eight were shown to contain enteric viruses (4.6%): four of these were adenovirus (2.3%), three were rotavirus (1.7%), and one represented a genogroup II norovirus (0.6%). Most of the positive samples were obtained from children under the age of seven. The most common additional clinical symptoms in pediatric patients with viral agents were fever, vomiting, and abdominal pain. Conclusions: Adenovirus and rotavirus were rarely found as agents responsible for gastroenteritis in central Iran. Although we show that the frequency of viral gastroenteritis is low in this area compared to bacterial gastroenteritis, still longer-term monitoring of all enteropathogenic agents should provide a deeper understanding of the real endemicity and the possible occurrence of unexpected outbreaks of viral enteritis.

show abstract

“…We will check the suggested reference and revise our manuscript accordingly. Our study result showed higher norovirus infection incidence than previous studies mentioning incidence about 17 13 We involve 94 subjects in this study and 31 subjects (32.9%) were norovirus positive. We will revise our manuscript.…”

Section: Hirokazu Kimuracontrasting

confidence: 45%

Norovirus genogroup correlation with acute diarrhea severity in Indonesian pediatric patients aged 1-60 months: a cross-sectional study

et al. 2019

View full text Add to dashboard Cite

Background: The objective of this study was to investigate the correlation between norovirus genogroup and severity of acute diarrhea in pediatric patients at the Dr. Soetomo Hospital, Surabaya, Indonesia. Methods: This cross-sectional study involved 31 participants aged 1-60 months admitted to the hospital with acute diarrhea from April 2012 to March 2013. Norovirus genogroups (GI and II) were identified from patient stool using reverse transcription polymerase chain reaction (RT-PCR). Severity was measured using the Ruuska and Vesikari scoring system. Results: In total, 91 stool samples were obtained, of which 31 (19%) were norovirus positive. Norovirus GI was found in one sample with mild diarrhea. Norovirus GII was found in 30 samples (96.8%); one sample with mild diarrhea (3.3%), 20 samples with moderate diarrhea (66.7%), and nine samples with severe diarrhea (30%). Conclusion: Norovirus GII was the most prevalent cause of acute diarrhea and 30% of the cases manifested as severe diarrhea.

show abstract

Epidemiological Surveillance of Norovirus Diarrhea in Hospitalized Children with Acute Gastroenteritis in South of Iran

Cited by 4 publications

References 19 publications

Viral Agents of Diarrhea in Young Children in Two Primary Health Centers in Edo State, Nigeria

Viral Agents of Diarrhea in Young Children in Two Primary Health Centers in Edo State, Nigeria

Low Endemic Frequency of Adenovirus, Rotavirus and Norovirus in Pediatric Diarrhea Samples from Central Iran

Norovirus genogroup correlation with acute diarrhea severity in Indonesian pediatric patients aged 1-60 months: a cross-sectional study

Contact Info

Product

Resources

About