Epidemiological Survey of Definite Cases of Meniere�s Disease Collected by the Seventeen Members of the Meniere�s Disease Research Committee of Japan in 1975�19761

Mizukoshi, K.; Ino, H.; Ishikawa, Kazuhiko; Watanabe, Yasuhiro; Yamazaki, Hiroki; Kato, Isao; Okubo, Jin; Watanabe, Isamu

doi:10.1159/000402925

Cited by 14 publications

(7 citation statements)

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“…Later studies revealed that 2.5 to 14% of patients with MD had a hereditary predisposition. (3,5,7) The three siblings with MD symptoms described by Brown (14) in 1949 were children of first cousins, which suggested an autosomal recessive mode of transmission. The findings of Birgersson et al (3) were compatible with autosomal dominant inheritance, possibly with incomplete penetrance, in most of their families, whereas the pedigrees in a few families were congruent with autosomal recessive inheritance.…”

Section: Discussionmentioning

confidence: 98%

“…Familial MD was first described by Brown (1), with several authors confirming this observation (2Y6). In a Japanese study of 520 patients with MD, 5.8% had close relatives who have the disease (7), and in a United Kingdom study comprising 190 patients with MD, 2.5% had family histories of MD (5). In two studies, the disease was classified as familial in origin in 14% (3) and 10.4% (8) of patients.…”

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confidence: 99%

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Familial Ménière's Disease in Five Generations

Frykholm

Larsen²,

Dahl³

et al. 2006

Otology &Amp; Neurotology

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The pattern of inheritance suggested that familial MD was autosomal dominant and exhibited incomplete expression of inner ear symptoms in some affected members. The decreasing age at onset of disease with succeeding generations could indicate anticipation. None of the hitherto-known DFNA loci, which has phenotypes bearing some resemblance to MD, had haplotypes in common with this large family affected by MD.

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Section: Discussionmentioning

confidence: 98%

mentioning

confidence: 99%

Familial Ménière's Disease in Five Generations

Frykholm

Larsen²,

Dahl³

et al. 2006

Otology &Amp; Neurotology

View full text Add to dashboard Cite

show abstract

“…5 MD is almost exclusively reported in adults, with \3% of cases estimated to occur at age \18 years. [33][34][35][36] The disease is most prevalent between ages 40 and 60 years, with peak onset in the 40s to 50s. [37][38][39][40][41][42] In a large US claimsbased study, the prevalence increased with age, ranging from 61 per 100,000 patients aged 18 to 34 years to 440 per 100,000 patients aged .65 years.…”

Section: Guideline Purposementioning

confidence: 99%

Clinical Practice Guideline: Ménière’s Disease

Basura

Adams

Monfared

et al. 2020

Otolaryngol.--head neck surg.

219

207

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Objective Ménière’s disease (MD) is a clinical condition defined by spontaneous vertigo attacks (each lasting 20 minutes to 12 hours) with documented low- to midfrequency sensorineural hearing loss in the affected ear before, during, or after one of the episodes of vertigo. It also presents with fluctuating aural symptoms (hearing loss, tinnitus, or ear fullness) in the affected ear. The underlying etiology of MD is not completely clear, yet it has been associated with inner ear fluid (endolymph) volume increases, culminating in episodic ear symptoms (vertigo, fluctuating hearing loss, tinnitus, and aural fullness). Physical examination findings are often unremarkable, and audiometric testing may or may not show low- to midfrequency sensorineural hearing loss. Conventional imaging, if performed, is also typically normal. The goals of MD treatment are to prevent or reduce vertigo severity and frequency; relieve or prevent hearing loss, tinnitus, and aural fullness; and improve quality of life. Treatment approaches to MD are many and typically include modifications of lifestyle factors (eg, diet) and medical, surgical, or a combination of therapies. Purpose The primary purpose of this clinical practice guideline is to improve the quality of the diagnostic workup and treatment outcomes of MD. To achieve this purpose, the goals of this guideline are to use the best available published scientific and/or clinical evidence to enhance diagnostic accuracy and appropriate therapeutic interventions (medical and surgical) while reducing unindicated diagnostic testing and/or imaging.

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“…5 MD is almost exclusively reported in adults, with \3% of cases estimated to occur at age \18 years. [33][34][35][36] The disease is most prevalent between 40 to 60 years, with peak onset in the 40 to 50s. [37][38][39][40][41][42] In a large US claims-based study, the prevalence increased with age, ranging from 61 per 100,000 in patients 18 to 34 years old to 440 per 100,000 for patients aged .65 years.…”

Section: Guideline Purposementioning

confidence: 99%

“…[37][38][39][40][41][42] In a large US claims-based study, the prevalence increased with age, ranging from 61 per 100,000 in patients 18 to 34 years old to 440 per 100,000 for patients aged .65 years. 30 Despite differences, most studies cite either an equal prevalence between males and females or a slightly higher prevalence of MD in women than in men, 14,35,38,41,42 with a reported female:male ratio in the United States of 1.89:1. 30 Data on the prevalence of bilateral MD yield variable estimates.…”

Section: Guideline Purposementioning

confidence: 99%

Clinical Practice Guideline: Ménière’s Disease Executive Summary

Basura

Adams

Monfared

et al. 2020

Otolaryngol.--head neck surg.

View full text Add to dashboard Cite

Objective Ménière’s disease (MD) is a clinical condition defined by spontaneous vertigo attacks (each lasting 20 minutes to 12 hours) with documented low- to midfrequency sensorineural hearing loss in the affected ear before, during, or after one of the episodes of vertigo. It also presents with fluctuating aural symptoms (hearing loss, tinnitus, or ear fullness) in the affected ear. The underlying etiology of MD is not completely clear, yet it has been associated with inner ear fluid volume increases, culminating in episodic ear symptoms (vertigo, fluctuating hearing loss, tinnitus, and aural fullness). Physical examination findings are often unremarkable, and audiometric testing may or may not show low- to midfrequency sensorineural hearing loss. Imaging, if performed, is also typically normal. The goals of MD treatment are to prevent or reduce vertigo severity and frequency; relieve or prevent hearing loss, tinnitus, and aural fullness; and improve quality of life. Treatment approaches to MD are many, and approaches typically include modifications of lifestyle factors (eg, diet) and medical, surgical, or a combination of therapies. Purpose The primary purpose of this clinical practice guideline is to improve the quality of the diagnostic workup and treatment outcomes of MD. To achieve this purpose, the goals of this guideline are to use the best available published scientific and/or clinical evidence to enhance diagnostic accuracy and appropriate therapeutic interventions (medical and surgical) while reducing unindicated diagnostic testing and/or imaging.

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Epidemiological Survey of Definite Cases of Meniere�s Disease Collected by the Seventeen Members of the Meniere�s Disease Research Committee of Japan in 1975�19761

Cited by 14 publications

References 0 publications

Familial Ménière's Disease in Five Generations

Familial Ménière's Disease in Five Generations

Clinical Practice Guideline: Ménière’s Disease

Clinical Practice Guideline: Ménière’s Disease Executive Summary

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