Epidemiologie des Konsums von neuen psychoaktiven Substanzen

Sumnall, Harry

doi:10.1007/978-3-642-55125-3_94

Cited by 1 publication

(1 citation statement)

References 22 publications

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“…We further followed the approach by Morris and Wallach (2014) and focused on uncompetitive NMDA-receptor antagonists and their analogues and thus excluded selective kappa opioid receptor (KOR) agonists like Salvinorin A, as it may not be regarded as dissociative in the narrow sense due to its specific psychoactive and pharmacodynamic features (see Betzler and Majić, 2017;Johnson, MacLean, Reissig, Prisinzano, & Griffiths, 2011). Mixed NMDA-receptor antagonist/KOR agonists and classic psychedelics with minor epidemiological relevance (see Sumnall, 2018) were excluded as well. The questions assessing the age of first-time substance listed ages 9 to 25 as well as the option "older than 25".…”

Section: Substance Usementioning

confidence: 99%

The link between childhood trauma and dissociation in frequent users of classic psychedelics and dissociatives

Thal

Daniels

Jungaberle³

2019

Journal of Substance Use

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Background: Childhood trauma severity is associated with the level of subsequent substance use as well as with the self-reported severity of dissociation. Classic psychedelics and dissociatives target neurotransmitter systems thought to be involved in the onset of dissociative symptoms and may evoke severe and long-lasting symptoms of depersonalization in some users. However, it is currently unclear whether drug use puts people with a history of childhood trauma at higher risk of developing dissociative symptoms. Objectives: The current study investigates whether the one-year prevalence of substance use significantly moderates the link between childhood trauma and the severity of depersonalization. Methods: Participants (n = 297, of which 80.2% were active users) filled out an online self-report questionnaire including the Childhood Trauma Questionnaire (CTQ), the Cambridge Depersonalisation Scale (CDS), and information about their substance use. Results: Results indicate that childhood trauma and substance use are significant individual predictors of dissociation scores in this sample, but no moderation of substance use on the link between childhood trauma and depersonalization was established. Conclusions: It is hypothesized that the quality (particularly the context) of the experience of substance use rather than the sheer quantity may be responsible for the manifestation of depersonalization.

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