Epidemiology, aetiology and outcomes of acute pancreatitis: A retrospective cohort study

Nesvaderani, Maryam; Eslick, Guy D.; Vagg, Daniel; Faraj, Shadi; Cox, Michael R.

doi:10.1016/j.ijsu.2015.07.701

Cited by 110 publications

(93 citation statements)

References 34 publications

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“…Mortality due to AP which has been reported in recent years ranges from 1% in Australia [23], 1.1% in Germany, up to 11% in the United Kingdom [1]; and in the Kielce region of Poland, it is 3.9%. The mortality rate due to the severe form of the disease reached 52.9% [13].…”

Section: Clinical Course Of Acute Pancreatitismentioning

confidence: 97%

“…In a large group of patients (41%) the cause of AP was not determined [13]. A high percentage of unexplained causes of the disease has been reported not only in Polish but also in international research [1,23]. Alcohol is a frequent cause of the disease in young Poles, mainly males, whereas gallstones is common among older females [13].…”

Section: Causes Of Morbiditymentioning

confidence: 99%

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Epidemiology of acute pancreatitis in Poland – selected problems

Kozieł¹,

Głuszek²

2016

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In recent years in many European countries, an increase has been observed in the incidence of acute pancreatitis (AP). Analysis of the results of scarce Polish epidemiological studies suggests that Poland belongs to the countries with the highest incidence rate -72.1/100 000. The incidence rate in the Kielce region is 99.9/100 000 and 79.7/100 000 patients who experienced the first episode of pancreatitis. The main cause of contracting the disease is gallstones, responsible for 34% of cases, while alcohol is the cause of AP in 24.1% of patients. In recent years, an increase has been noted in the incidence of AP with a severe course. Although in the majority of patients the course of the disease is mild, in the severe form mortality remains within the range 30-60%. StreszczenieW ostatnich latach obserwuje się wzrost zachorowań na ostre zapalenie trzustki (OZT) w wielu krajach. Analiza wyników nielicznych polskich badań epidemiologicznych pozwala przypuszczać, że Polska należy do krajów o jednym z najwyższych współczynników zachorowalności -72,1/100 000. Współczynnik zachorowalności w województwie świętokrzyskim wynosi 99,9/100 000. Po raz pierwszy na OZT chorowało 79,7/100 000 osób. Główną przyczyną zachorowania polskich pacjentów jest kamica żółciowa, która odpowiada za 34% przypadków. Alkohol jest przyczyną OZT u 24,1% chorych. Stwierdza się ponadto wzrost częstości występowania OZT o ciężkim przebiegu. Chociaż u większości pacjentów choroba ma przebieg łagodny, to w przypadku ciężkiej postaci śmiertelność kształtuje się na poziomie 30-60%.

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Section: Clinical Course Of Acute Pancreatitismentioning

confidence: 97%

Section: Causes Of Morbiditymentioning

confidence: 99%

Epidemiology of acute pancreatitis in Poland – selected problems

Kozieł¹,

Głuszek²

2016

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“…Acute Pancreatitis (AP) is a medical emergency that can vary in presentation from mild-or self-limiting disease to severe or fatal when it extends beyond the pancreas to cause multiorgan damage. Understanding the pattern of the disease including the etiology, severity, mortality, and its predictors in a given population is essential in guiding the management, preventing recurrence, decreasing morbidity and mortality, and ensuring optimal delivery of care [1]. However, epidemiological studies that address these factors, especially in the Middle East, are lacking significantly.…”

Section: Introductionmentioning

confidence: 99%

Acute Pancreatitis: An Exploratory, Cross-sectional, Single-center Study of the Epidemiological Features of the Disease in a Sample of Saudi Patients

Lehibi¹,

Wani²,

Mtawa³

et al. 2019

JEGH

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Epidemiological studies on Acute Pancreatitis (AP) are significantly scarce in the Saudi Arabian Literature. In this paper, we aim to explore the current trends of AP in a sample of Saudi patients. This is a cross-sectional study in which we reviewed AP-related admissions from 2014 to 2017. Data collected included demographics, clinical presentation, investigations, severity, complications, and the outcome at the end of hospitalization. During the study period, 107 patients were admitted due to AP. Fifty-seven (53%) were males. Biliary pancreatitis was the most common etiology found among our patients (39.3%; 95% CI: 30.5-48.7), followed by alcoholic pancreatitis (11.2%; 95% CI: 6.5-18.6) and hypertriglyceridemia (8%; 95% CI: 4.5-15.2). Pancreatic pseudocysts were the most common complication we found in this series (15%; 95% CI: 9.4-23). Of all the hospitalized patients in this study, eight patients (7.9%) died (95% CI: 3.8-14.1). The number of AP-related admissions and mortality rate appear to have increased as compared with the numbers in earlier national studies. The etiological groups have also changed. As compared with Western/Asian studies, however, there was almost no difference in the epidemiological patterns except for the mortality rate.

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“…Less common causes include trauma, secondary to iatrogenic procedures (post-ERCP), hypercholesterolemia, drug/medications (corticosteroids, azathioprine), or idiopathic causes [5].…”

Section: Introductionmentioning

confidence: 99%

Disappearing portal venous gas in acute pancreatitis and small bowel ischemia

McNicholas

Kelly

Das

et al. 2017

Radiology Case Reports

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We report an usual case of hepatic portal venous gas (HPVG) in the setting of acute pancreatitis and small bowel ischemia. Interestingly, the HPVG disappeared within 2 hours of the original computed tomography scan, despite the patient having small bowel ischemia. The patient had a complicated clinical course, dying 62 days postadmission. This case highlights that HPVG in setting of acute pancreatitis and small bowel ischemia has a very high morbidity and mortality, requiring early detection and aggressive surgical management.

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Epidemiology, aetiology and outcomes of acute pancreatitis: A retrospective cohort study

Abstract: The majority of patients with acute pancreatitis in Western Sydney present with mild disease and have a low risk of morbidity or mortality. The ratio of gallstone to alcohol aetiology was 2:1. Idiopathic pancreatitis is responsible for more cases than expected.

Cited by 110 publications

References 34 publications

Epidemiology of acute pancreatitis in Poland – selected problems

Epidemiology of acute pancreatitis in Poland – selected problems

Acute Pancreatitis: An Exploratory, Cross-sectional, Single-center Study of the Epidemiological Features of the Disease in a Sample of Saudi Patients

Disappearing portal venous gas in acute pancreatitis and small bowel ischemia

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