This study is an analysis of cancer incidence among people aged 15 and over in North Cyprus (NC) with aim of helping to establish a cancer control plan based on the results. METHODS Data from 2010 to 2014 were obtained from Near East University (NEU) Hospital. Crude incidence rate (CIR) and age-standardized rate (ASR) per 100,000 were calculated for 28 different cancers for males and females. In line with GLOBOCAN 2012, ASR values for 2012 in NC were compared with South Cyprus (SC) and Southern Europe (SE). RESULTS Total of 1,782 cancer cases were diagnosed. ASR value was 180.61 and 192.75 per 100,000 person-years for males and females, respectively. Most prevalent male (M) cancers were lung, prostate, colorectal, thyroid, and bladder. Similarly, for females (F), they were breast, thyroid, colorectal, lung, and non-melanoma skin cancer. Thyroid cancer in females in NC was more prevalent than in SE. Breast (F), prostate, colorectal (F), bladder (M), and ovary and corpus were less frequent than in SE and SC; cervix, larynx (M), brain (M) and colorectal (M) only were less frequent than in SE, and the remainder were statistically similar. CONCLUSION Possible risk factors for the most common cancers in NC have been discussed; however, etiopathogenetic scientific results are still needed. Risk factor studies should be performed to raise public awareness and to plan future cancer prevention measures. The development of active cancer registry centers and combining data under a single cancer organization is recommended.