2015
DOI: 10.1016/j.giec.2015.02.010
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Epidemiology and Risk Factors for Upper Gastrointestinal Bleeding

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Cited by 128 publications
(130 citation statements)
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References 53 publications
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“…More serious side effects, such as gastrointestinal ulceration and upper GI bleeding (UGIB) are less common, but remain well known risks of NSAID use [13]. With chronic use of NSAIDs, 15-30 % of patients will develop peptic ulcer disease [13].…”
Section: Gastrointestinal (Gi) Effectsmentioning
confidence: 99%
See 1 more Smart Citation
“…More serious side effects, such as gastrointestinal ulceration and upper GI bleeding (UGIB) are less common, but remain well known risks of NSAID use [13]. With chronic use of NSAIDs, 15-30 % of patients will develop peptic ulcer disease [13].…”
Section: Gastrointestinal (Gi) Effectsmentioning
confidence: 99%
“…More serious side effects, such as gastrointestinal ulceration and upper GI bleeding (UGIB) are less common, but remain well known risks of NSAID use [13]. With chronic use of NSAIDs, 15-30 % of patients will develop peptic ulcer disease [13]. Use of all non-selective NSAIDs raises the risk of UGIB with a relative risk of 4.27 with a 95 % CI of 4.11-4.44 [13].…”
Section: Gastrointestinal (Gi) Effectsmentioning
confidence: 99%
“…При возникновении на фоне приема НПВП язвы и / или кровотечения из верхних отделов ЖКТ показа-но тестирование на наличие этой инфекции, а при ее выявлении -проведение курса эрадикационной те-рапии [22]. В последующем оправдано использование ингибиторов протонной помпы -традиционных га-стропротекторов, предупреждающих развитие дис-пепсии, эрозий, язв и ЖКТ-кровотечений [23,24], а также ребамипида -цитопротективного противо-воспалительного препарата, особенно при наличии также НПВП-энтеропатии [25,26].…”
Section: Discussionunclassified
“…Esta información es muy útil para los clínicos, puesto que es probable que otras comorbilidades sean los principales factores de riesgo hacia el desarrollo de sangrado y no la enfermedad renal crónica. Entre estos, la asociación fue mucho más clara en presencia de trombocitopenia y el antecedente de ulcera gástrica activa (29)(30)(31).…”
Section: Discussionunclassified