Epidemiology and risk factors of retinoblastoma in Chongqing area

Yang, Yuqiong; Li, Jia; Yuan, Hongfeng

doi:10.18240/ijo.2016.07.08

Cited by 5 publications

(1 citation statement)

References 20 publications

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“…The incidence of retinoblastoma is related to the interaction of many factors, for example, where the parents live in city, the presence of pets during pregnancy mainly cat and dog, and exposure to hazardous chemicals from the father six months before pregnancy (paint, leather equipment, decoration, electronic accessories, benzene, formaldehyde and other heavy metals. 16 Cases of nonheritable retinoblastoma have unilateral tumors, unlike heritable retinoblastoma, which often develops bilaterally and multifocally. The most cases about two-thirds of all cases were unilateral retinoblastoma.…”

Section: Resultsmentioning

confidence: 99%

Enucleation for retinoblastoma in a 22-month-old boy

Ningtyas,

Irawan

2023

J. Teknol. Laboratorium

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Retinoblastoma is the commonest intraocular tumor in childhood. Management of retinoblastoma is quite complex depending on the stage, visual and globe saving, psychosocial factors, modality of treatment, and health infrastructure. We report a case of retinoblastoma in a child in a limited health facility without a pediatric oncologist or ophthalmology oncologist. A 22-month old boy came with complaints of leukocoria which his parents had known since the previous week. Ultrasonography of the eye shows calcification on the retina that supports Group E retinoblastoma. Bone marrow aspiration and MRI cannot be performed due to limited resources. Even though the parents only noticed the symptoms for a week and immediately brought to the ophthalmologist, the retinoblastoma stage was already in Group E. Enucleation and globe salvage were unavoidable. Enucleation was performed on the patient with histopathology finding the presence of Flexner-Wintersteiner rosette cells. After enucleation, he was referred to the oncologist for adjuvant chemotherapy. Early retinoblastoma detection is crucial in increasing the cure rate while maintaining children's vision.

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Section: Resultsmentioning

confidence: 99%

Enucleation for retinoblastoma in a 22-month-old boy

Ningtyas,

Irawan

2023

J. Teknol. Laboratorium

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LncRNA NKILA Inhibits Retinoblastoma by Downregulating lncRNA XIST

Lyu

et al. 2019

Current Eye Research

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Parental Occupation and Risk of Childhood Retinoblastoma in Denmark

Omidakhsh

Hansen

Ritz

et al. 2020

Journal of Occupational &Amp; Environmental Medicine

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Objective: Retinoblastoma is the most common primary intraocular tumor affecting children. We examine the role of parental occupational exposures and risk of retinoblastoma among offspring.Methods: Our population-based case-control study linked data from four nationwide Danish registries and included all cases of retinoblastoma diagnosed in Danish children (<5 years, n=144) between 1975-2014. We focused on two biologically relevant time periods: 90 days preconception to conception for fathers; conception to birth for mothers. Parents were grouped into major industry headings created from Danish industry codes. Results:We observed increased risk of all retinoblastoma for children of fathers in the food and drink industry and iron and metal industry. Bilateral disease was associated with paternal work in manufacturing and land transportation. Conclusion:Our results suggest that some occupational exposures may increase the risk of childhood sporadic retinoblastoma.

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Epidemiology and risk factors of retinoblastoma in Chongqing area

Abstract: The living place of parents, mother who feed pets before pregnancy, exposure to harmful chemicals of father before pregnancy were the risk factors of retinoblastoma which affects the occurrence of retinoblastoma in a certain extent.

Cited by 5 publications

References 20 publications

Enucleation for retinoblastoma in a 22-month-old boy

Enucleation for retinoblastoma in a 22-month-old boy

LncRNA NKILA Inhibits Retinoblastoma by Downregulating lncRNA XIST

Parental Occupation and Risk of Childhood Retinoblastoma in Denmark

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