Epidemiology, clinical features and prognostic value of HIV‐1 related oral lesions

Abstract

Between February 1987 and February 1990, we studied 737 antibody anti HIV-1 positive (AbHIV+) subjects referred to the Infectious Diseases Institute of the University of Turin (Italy) in order to evaluate types, prevalences, relations with clinical stages, distributions in risk-groups and prognostic significances of HIV-1 related oral lesions. The study evidenced the high prevalence of oral lesions, especially mycoses, in the investigated population: 40.3% of the patients showed, in fact, HIV-1 related oral lesions. The 37 months follow-up of 55 AbHIV+ with oral hairy leukoplakia (HL) and 101 patients with oral candidiasis (OC), demonstrated that the probability of developing AIDS in patient with HL was 0.381 at 15, 0.635 at 25 and 0.824 at 37 months. In the patients with OC the probability was 0.294 at 15 months, 0.524 at 25 and 0.781 at 37 months.

Oral lesions and conditions associated with human immunodeficiency virus infection in 300 south Indian patients

“…In our study, the most frequently encountered variant of candidiasis was the pseudomembranous type, contrary to prevalence studies of oral lesions, where EC has been reported to be the most common type of OC in HIVinfected individuals. [30][31][32][33] However, this is consistent with the findings reported by other investigators. 29,34 We also observed a higher prevalence of PC in males than in females (17.7% and 10.6%, respectively; P <0.05).…”

Access to Oral Health Care and Treatment Needs of HIV Positive Paediatric Patients

“…Using the CPITN index score for the overall periodontal status and treatment needs, 46 (83.6%) of the children had CPITN score of zero (0), while 8(14.5%) had a score of 1, and 1(1.8%) had a score of two (2). The prevalence of plaque was not signifi cantly associated with age (p=0.49).…”

“…The age at the erupti on of Immune defects in children whether caused by primary immunodefi ciency, immunodefi ciency virus infecti on or immunosuppressive therapy has been shown to have profound eff ects on the oral ti ssues 1 . Oral lesions, especially oral candidiasis, may frequently be the initi al presenti ng signs of HIV infecti on 2 . An understanding of manifestati ons of oral disease is becoming increasingly important 3 .…”

Prevalência de colonização e infecção bucal por Candida e de cárie não-tratada em pacientes pediátricos com aids

“…Nas crianças, em particular, além do sistema imunológico imaturo, o decréscimo desse tipo de linfócitos favorece a progressão da doença (BROWN et al, 2000;MONIACI et al, 1990).…”