Epidemiology of Acute Symptomatic Seizures among Adult Medical Admissions

Nwani, Paul; Nwosu, MC; Nwosu, Monica Nonyelum

doi:10.1155/2016/4718372

Cited by 16 publications

(13 citation statements)

References 20 publications

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“…Acute symptomatic seizures can occur in the setting of systemic illness and sepsis (14), proposing a systemic inflammatory response leading to a decreased seizure threshold. The six patients who presented with first-time seizure of life had high inflammatory markers known to be elevated in COVID-19 infection, which suggests that these seizures could be categorized as provoked seizures in the setting of robust systemic inflammatory response.…”

Section: Discussionmentioning

confidence: 99%

Inpatient Neurology Consultations During the Onset of the SARS-CoV-2 New York City Pandemic: A Single Center Case Series

et al. 2020

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Objective: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) primarily causes respiratory illness. However, neurological sequelae from novel coronavirus disease 2019 (COVID-19) can occur. Patients with neurological conditions may be at higher risk of developing worsening of their underlying problem. Here we document our initial experiences as neurologic consultants at a single center quaternary hospital at the epicenter of the COVID-19 pandemic. Methods: This was a retrospective case series of adult patients diagnosed with SARS-CoV-2 who required neurological evaluation in the form of a consultation or primary neurological care from March 13, 2020 to April 1, 2020. Results: Thirty-three patients (ages 17-88 years) with COVID-19 infection who required neurological or admission to a primary neurology team were included in this study. The encountered neurological problems associated with SARS-CoV-2 infection were encephalopathy (12 patients, 36.4%), seizure (9 patients, 27.2%), stroke (5 patients, 15.2%), recrudescence of prior neurological disease symptoms (4 patients, 12.1%), and neuromuscular (3 patients, 9.1%). The majority of patients who required evaluation by neurology had elevated inflammatory markers. Twenty-one (63.6%) patients were discharged from the hospital and 12 (36.4%) died from COVID-19 related complications. Conclusion: This small case series of our initial encounters with COVID-19 infection describes a range of neurological complications which are similar to presentations seen with other critical illnesses. COVID-19 infection did not change the overall management of neurological problems.

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Section: Discussionmentioning

confidence: 99%

Inpatient Neurology Consultations During the Onset of the SARS-CoV-2 New York City Pandemic: A Single Center Case Series

et al. 2020

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“…Neuroinfection was predominant in patients below 50 years of age while stroke was more in those aged 50 and above. HIV infection was the etiological risk factor for 12% of cases [10].…”

Section: Acute Symptomatic Seizuresmentioning

confidence: 99%

Epidemiology of early stages of epilepsy: Risk of seizure recurrence after a first seizure

Rizvi

Ladino

Hernández-Ronquillo

et al. 2017

Seizure

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A single unprovoked seizure is a frequent phenomenon in the general population and the rate of seizure recurrence can vary widely. Individual risk prognostication is crucial in predicting patient outcomes and guiding treatment decisions. In this article, we review the most important risk factors associated with an increased likelihood of seizure recurrence after a single unprovoked seizure. In summary, the presence of focal seizure, nocturnal seizure, history of prior brain injury, family history of epilepsy, abnormal neurological exam, epileptiform discharges on electroencephalography and neuroimaging abnormalities, portend increased risk of seizure recurrence. Elucidation of these risk factors in patient assessment will augment clinical decision-making and may help determine the appropriateness of instituting anti-epilepsy treatment. We also discuss the Canadian model of single seizure clinics and the potential use to assess these patients.

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“…16 In developing countries, infections are the leading cause of acute symptomatic seizures in both adults and children. 25,32 Common infections resulting in seizures are bacterial meningitis, viral encephalitis, cerebral abscesses, and endocarditis. In patients with bacterial meningitis, seizures occur in 5 to 27% of patients and tend to occur early in the disease.…”

Section: Infectionsmentioning

confidence: 99%

Acute Provoked Seizures—Work-Up and Management in Adults

Moosavi

Swisher

2020

Semin Neurol

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Acute provoked seizures, also known as acute symptomatic seizures, occur secondary to a neurological or systemic precipitant, commonly presenting as a first-time seizure. In this article, we will discuss etiology, emergent protocols, medical work-up, initial treatment, and management of these seizures. The definitions, classifications, and management of convulsive status epilepticus and nonconvulsive status epilepticus in an acute setting will also be reviewed.

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Epidemiology of Acute Symptomatic Seizures among Adult Medical Admissions

Cited by 16 publications

References 20 publications

Inpatient Neurology Consultations During the Onset of the SARS-CoV-2 New York City Pandemic: A Single Center Case Series

Inpatient Neurology Consultations During the Onset of the SARS-CoV-2 New York City Pandemic: A Single Center Case Series

Epidemiology of early stages of epilepsy: Risk of seizure recurrence after a first seizure

Acute Provoked Seizures—Work-Up and Management in Adults

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