Epidemiology of Aluminium Toxicity in a �Low Incidence� Area

Winney, R. J.; Cowie, J. F.; Cumming, Allan D.; Short, Antoni; Smith, Gerald D.; Robson, J. M.

doi:10.1159/000408066

Cited by 5 publications

(2 citation statements)

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“…Microcytic hypochromic anemia, an early hematolog ical manifestation of aluminum intoxication, is an useful index to detect affected patients [11], With a fall in serum aluminum subsequent to a reduction in aluminum in gress, the anemia improves [12,13].…”

Section: Clinical and Pathophysiologic Featuresmentioning

confidence: 99%

Risk Factors in Aluminum Toxicity in Children with Chronic Renal Failure

Santos

Massie

Chan³

1986

Nephron

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Section: Clinical and Pathophysiologic Featuresmentioning

confidence: 99%

Risk Factors in Aluminum Toxicity in Children with Chronic Renal Failure

Santos

Massie

Chan³

1986

Nephron

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“…5-7 Therefore, regular measurement of serum and dialysis fluid aluminum concentration is of considerable value in order to determine aluminum exposure and as a guide to the risk of toxicity in long-term haemodialysis patients. 7,8 Atomic absorption spectroscopy (AAS) is the method most widely used for routine aluminum determination in plasma or serum. 9,10 Nevertheless, several investigators have applied neutron activation analysis to determine aluminum content in biological materials.…”

Section: Introductionmentioning

confidence: 99%

Serum aluminum determination by instrumental neutron activation analysis in long-term haemodialysis patients

Stamatelatos

Katopodis

Bersos

et al. 1999

J Radioanal Nucl Chem

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Serum aluminum levels were determined by instrumental neutron activation analysis in 31 patients undergoing long-term haemodialysis. Aluminum-28 1.778 MeV (Tj/2 = 2.24 min) "/-rays produced by the thermal neutron reaction 27Al(n,'f)28AI were detected. Successive irradiation of the samples at epithermal neutron fluence was performed to correct for the interference from the fast neutron reaction 3tp(n,cQ28Al. Serum aluminum level in this group of subjects was adequately represented by a lognormal distribution with a mean and variance of 16.5 ~tg/l and 16.8 gg/I, respectively. The results obtained were found to be in agreement with serum aluminum determination performed by electrothermal atomic absorption spectrophotometry (r 2 = 0.97). Instrumental neutron activation can provide a rapid technique to routinely monitor long-term haemodialysis patients in order to identify individuals at greater risk to develop aluminum toxicity.

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Periosteal new bone in patients on intermittent haemodialysis: An early indicator of aluminium-induced osteomalacia?

Chambers

Winney

1985

Clinical Radiology

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Epidemiology of Aluminium Toxicity in a �Low Incidence� Area

Cited by 5 publications

References 0 publications

Risk Factors in Aluminum Toxicity in Children with Chronic Renal Failure

Risk Factors in Aluminum Toxicity in Children with Chronic Renal Failure

Serum aluminum determination by instrumental neutron activation analysis in long-term haemodialysis patients

Periosteal new bone in patients on intermittent haemodialysis: An early indicator of aluminium-induced osteomalacia?

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