Epidemiology of Bone Tumors in Lebanon: a Retrospective Study From 2000 to 2022 at a Tertiary Center

Abstract

Aim: Bone tumors are rare and have an uneven geographic distribution. Methods: 730 patients diagnosed with bone tumors were included in this retrospective analysis. Results: With a 64% rate of malignancy, the most common tumors were metastasis (40%) mostly in the axial skeleton, Osteosarcoma (9%) mostly in the femur, Osteochondroma (8%) mostly in the femur, giant cell tumors (7%) mostly in the knee, and Ewing's sarcoma (6%) mostly in the axial skeleton. Conclusion: Even though a some of the tumors have a predilection for certain localizations in the human body, they may differ in the middle-eastern population. One must also pay attention to the higher rates of malignancies as compared with other cohorts.

Trends in primary malignant bone cancer incidence and mortality in the United States, 2000–2017: A population-based study

“…Another study from Brazil [11] showed that the median incidence rates of bone tumors were 5.74 and 11.25 per million in children and young adults respectively, while the corresponding median mortality rates were 1.22 and 5.07 deaths per million. An analysis of epidemiological data related to bone tumors in Lebanon from 2000 to 2022 reported a total of 730 bone tumor diagnoses, of which 64 % were malignant and 40 % were metastases [12] .…”

Tyrosine kinase inhibitors in osteosarcoma: Adapting treatment strategiesa

“…OS is the most frequent malignant bone tumor and it occurs most frequently in young males and typically develops in the long bones of the appendicular skeleton. In most cases, the cause of OS has remained unknown [2] , [3] . The association between OS and accelerated bone proliferation is suggested by the frequent occurrence of OS during the pubertal growth spurt phase and at the locations of greatest osteoformation.…”