Epidemiology of cancer of the cervix. II. Marital and coital factors in cervical cancer.

Martin, Charmaine

doi:10.2105/ajph.57.5.803

Cited by 117 publications

(5 citation statements)

References 15 publications

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“…More than five decades of epidemiological evaluation has indisputably determined its relationship to the sexual habits of women and their partners; [4] as well as other characteristics, which constitute the risk profile associated with the greater probability of this cancer presenting in certain women [3]. …”

Section: Descriptive Aspects Of Cervical Cancer In Latin Americamentioning

confidence: 99%

“…This is a pathology that has been recognised for more than 50 years as being a disease linked to the sexual habits of women or their partners [3, 4, 5] and furthermore whose incidence clearly disproportionately impacts women from the poorest social strata, and the most economically disadvantaged regions [6]; to the extent that mortality rates from this cancer are three times higher in Latin America and the Caribbean than in the United States and Canada [2]. …”

Section: Introductionmentioning

confidence: 99%

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Epidemiology of cervical cancer in Latin America

Negrin¹

2015

ecancer

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The basic aspects of the descriptive epidemiology of cervical cancer in Latin America are presented. A decrease in the incidence and mortality rates has been observed in the period from 2000 to 2012 in all countries across the region, this has not occurred at the same proportions, and in many countries, observed figures of incidence and mortality are among the highest levels in the world. In Latin America, calculating a mean measure of the numbers from the GLOBOCAN data from 2000 to 2012, we can observe a difference of up to fivefold of the incidence (Puerto Rico 9,73 Vs Bolivia 50,73) and almost seven times for mortality (Puerto Rico 3,3 Vs Nicaragua 21,67).A report of the epidemiology, risk factors, and evaluation of screening procedures regarding the possible impact of the human papillomavirus (HPV) vaccine I in the prevention of cervical cancer is presented.

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Section: Descriptive Aspects Of Cervical Cancer In Latin Americamentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Epidemiology of cervical cancer in Latin America

Negrin¹

2015

ecancer

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“…Cervical cancer is almost generally considered to be caused by a venereally transmitted carcinogen (Terris and Oalman, 1960;Rotkin, 1967Rotkin, ,1973Martin, 1967;Thomas, 1973;Kessler, 1976Kessler, , 1977 and most of the epidemiological evidence suggests involvement of a viral agent. Since 1968, herpes simplex type-2 virus (HSV-2) has been the agent most often suspected of being an essential factor in cervical neoplasia (see the reviews by Melnick and Adam, 1978;Nahmias and Sawanabori, 1978;Rawls et al, 1977).…”

mentioning

confidence: 99%

Prospective study on the relationship between cervical neoplasia and herpes simplex type‐2 virus. I. Epidemiological characteristics

Vonka

Kańka

Jelínek

et al. 1984

Intl Journal of Cancer

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To determine the risk associated with previous herpes simplex type-2 (HSV-2) infection and possibly other virus infections, a prospective study of cervical neoplasia in more than 10,000 women was performed in the 1975-1983 period. The subjects were selected at random from an alphabetical listing of eligible women living in one district of Prague. At enrollment colposcopy and cervical cytology were performed, a blood sample was taken and data regarding education, socio-economic status, personal habits and sexual and reproduction-associated attributes were obtained from each woman. A total of 10,683 women were enrolled; a complete set of data was obtained in 10,389 women. Women with normal or non-significant findings were invited for further colposcopical and cytological investigations after 2 years and 4 years, the other women were followed at 3- to 6-monthly intervals. In women with highly significant findings, histological investigation was performed. The total of 150 cases of moderate to severe dysplasia (i.e. cervical intraepithelial neoplasia, grade II, CIN II), 83 cases of carcinoma in situ (CIN III) and 21 cases of invasive carcinoma (INCA) were detected. More than 60% of the patients were ill at enrollment, the other cases developed in subjects with originally slightly suspicious (27 CIN II, 17 CIN III, 3 INCA) or negative findings (30 CIN II, 12 CIN III, 3 INCA). Analysis of the data indicated significantly positive correlation of one or more of these clinical conditions with a number of sexual and reproduction-related attributes of which early age at first intercourse was most consistent. Among the other attributes, the smoking habit was associated with the highest risk of developing the disease. A negative correlation of cervical neoplasia with several attributes was demonstrated; of these diathermoelectrocoagulation of the ectopic epithelium and transformation zone of cervix was the most important single protective factor. On the basis of these findings, control subjects were selected for serological studies.

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“…Although scientifically supported by epidemiological studies showing higher incidences in women who (themselves or their husbands) had a high number of sexual partners ( n > 2) [ 44 , 45 ] or were regularly involved in prostitution [ 46 , 47 ], all the attempts linking cervical cancer to sexually transmitted infections remained unsuccessful within the second half of the 19th century. Strikingly, the prevalence was lower among Jewish women and in women married to circumcised males [ 48 ].…”

Section: The Presence Of Oncogenic Viruses: From “Invisible Poison” T...mentioning

confidence: 99%

From Satirical Poems and Invisible Poisons to Radical Surgery and Organized Cervical Cancer Screening—A Historical Outline of Cervical Carcinoma and Its Relation to HPV Infection

Jung,

Klamminger,

Bier

et al. 2024

Life

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Over the last century, the narrative of cervical cancer history has become intricately tied to virus research, particularly the human papillomavirus (HPV) since the 1970s. The unequivocal proof of HPV’s causal role in cervical cancer has placed its detection at the heart of early screening programs across numerous countries. From a historical perspective, sexually transmitted genital warts have been already documented in ancient Latin literature; the remarkable symptoms and clinical descriptions of progressed cervical cancer can be traced back to Hippocrates and classical Greece. However, in the new era of medicine, it was not until the diagnostic–pathological accomplishments of Aurel Babeş and George Nicolas Papanicolaou, as well as the surgical accomplishments of Ernst Wertheim and Joe Vincent Meigs, that the prognosis and prevention of cervical carcinoma were significantly improved. Future developments will likely include extended primary prevention efforts consisting of better global access to vaccination programs as well as adapted methods for screening for precursor lesions, like the use of self-sampling HPV-tests. Furthermore, they may also advantageously involve additional novel diagnostic methods that could allow for both an unbiased approach to tissue diagnostics and the use of artificial-intelligence-based tools to support decision making.

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Epidemiology of cancer of the cervix. II. Marital and coital factors in cervical cancer.

Cited by 117 publications

References 15 publications

Epidemiology of cervical cancer in Latin America

Epidemiology of cervical cancer in Latin America

Prospective study on the relationship between cervical neoplasia and herpes simplex type‐2 virus. I. Epidemiological characteristics

From Satirical Poems and Invisible Poisons to Radical Surgery and Organized Cervical Cancer Screening—A Historical Outline of Cervical Carcinoma and Its Relation to HPV Infection

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