Epidemiology of chronic obstructive pulmonary disease: a population-based study in Krasnoyarsk region, Russia

Abstract

BackgroundKrasnoyarsk region is a territory with the widespread risk factors for chronic obstructive pulmonary disease (COPD) such as tobacco smoke, air pollution, and occupational exposure. An assessment of COPD prevalence based on medical diagnosis statistics underestimates the true COPD prevalence. This study aims to evaluate how medical examinations may increase the accuracy of estimates of COPD prevalence.MethodsTrue COPD prevalence was estimated as a number of patients with the established disease diagnosis supplemented by the additional disease cases detected during medical examinations per 1,000 inhabitants of the region. Official medical statistics data and the data collected from the Global Alliance against Chronic Respiratory Diseases program 2011 among 15,000 inhabitants of the region aged 18 years and older were analyzed.ResultsThis study revealed the COPD cases without official medical diagnosis. The true prevalence of COPD is estimated to be two times higher than the prevalence estimates based on medical diagnosis statistics.ConclusionUndiagnosed and untreated cases of COPD result in severe COPD forms as well as addition of severe comorbidities. Because of this, there is an increase in the index of potential years of life lost. Conducting special medical examinations may increase the number of COPD cases detected at the early stages of the disease. This, in turn, may reduce the overall burden of the disease for the population of the region.

Global prevalence of chronic obstructive pulmonary disease: systematic review and meta-analysis

“…Our meta-analysis also demonstrated a higher prevalence among men. This difference could be due to higher occupational risks (65) or higher rates of smoking among men (66). The highest prevalence of COPD was observed in the Region of the Americas and the lowest in the South-East Asia Region/Western Pacific Region.…”

Nonadherence to treatment and quality of life among patients with chronic obstructive pulmonary disease

“…[ 3 ] In North Africa and Middle East, COPD prevalence was about 3.6%. [ 4 ] In Egypt, it was estimated that COPD prevalence among high risk groups was 10%. [ 5 ]…”

Acute exacerbations as a poor prognostic factor of chronic obstructive pulmonary disease

“…Заболеваемость ХОБЛ различается в России в пределах 6-10 % [9]. Однако распространенность ХОБЛ в России, как и во многих других странах, недооценена, т. к. диагностируется только у ⅓ больных [10,11]. Ранее сообщалось, что согласно подтвержденным специалистами данным, распространенность ХОБЛ в Красноярском крае составляет 10,6 на 1 000 жителей региона [12].…”

“…Ранее сообщалось, что согласно подтвержденным специалистами данным, распространенность ХОБЛ в Красноярском крае составляет 10,6 на 1 000 жителей региона [12]. По оценкам исследователей Глобального альянса против хронических респираторных заболеваний (GARD, 2011), истинная распространенность ХОБЛ составляла приблизительно 15,3 %, что в 7-8 раз превосходит показатели, основанные на официальных данных [10].…”