Epidemiology of community-onset bloodstream infections in Bouaké, central Côte d’Ivoire

Abstract

Bacterial bloodstream infections (BSI) account for considerable morbidity worldwide, but epidemiological data from resource-constrained tropical settings are scarce. We analysed 293 blood cultures from patients presenting to a regional referral hospital in Bouaké, central Côte d’Ivoire, to determine the aetiology of community-onset BSI. The prevalence of bacteraemia was 22.5%, with children being most commonly affected. Enterobacteriaceae (predominantly Klebsiella pneumoniae and Salmonella enterica) accounted for 94% of BSI. Staphylococcus aureus was the only relevant Gram-positive pathogen. Clinical signs and symptoms were not significantly associated with blood culture positivity after controlling for malaria.

Multi-drug resistant, extended spectrum beta-lactamase and carbapenemase-producing bacterial isolates among children under five years old suspected bloodstream infection in a specialized Hospital in Ethiopia: Cross-sectional study

“…In this study, the most common causes of bloodstream infections were gram-negative bacteria, in particular Klebsiella pneumoniae 31.4 % followed by Acinitobacter species 8.7%. This was supported by the study done in Jimma Ethiopia 31.4% [37], Kenya 13% [38], Ghana 26% [39], Bouaké, central Côte d'Ivoire 22.5% [40] in Asian such as in India by 25.8%, 30.5% [41,42] in Brazil, Latin America…”

Multi-Drug Resistant, Extended Spectrum beta-Lactamase and Carbapenemase Producing Bacterial Isolates among Septicemia Suspected under Five Children in Tikur Anbesa Specialized Hospital, Addis Ababa Ethiopia: Cross-sectional study

“…In this study, the most common causes of bloodstream infections were gram-negative bacteria, in particular Klebsiellapneumoniae 31.4 % followed by Acinitobacter species 8.7% were the predominate among GNB isolates. This was supported by the study done in Jimma Ethiopia 31.4% [37],in African countries in Kenya 13% [38], Ghana 26% [39] , Bouaké, central Côte d'Ivoire 22.5% [40] in Asian such as in India by 25.8% ,30.5% [41,42] in Brazil, Latin America by Berezina et al [43], veitnam 20% [44] the most common isolate was Klebsiellapneumoniae. However it was inconsistent that the predominant GNB isolation rate varies from country to country where in India by Kante et al, [45], Indonesia by Murni et al, [46] frequently isolated pathogen in BSI was Pseudomonas other than Klebsiellapneumoniae in the same age group.…”

“…Among the total isolates 54% gram negative bacteria were causing blood stream infection in children which is in line with the previous study done in Addis Ababa, Ethiopia 51.8% [23] elsewhere in India 51.8% [32] Kabul, Afghanistan 51.7% [ 33] and in Nepal 55.2%, 56% [ 34] respectively but higher compared to the study done in USA by Larru.,et al,22%[35] and in South Africa by Crichton et al, 40.7% [36], this was due to difference in socioeconomic , geographical and infection control mechanisms.…”

Multi-Drug Resistant, Extended Spectrum β-Lactamase and Carbapenemase Producing Bacterial Isolates among Septicemia Suspected under Five Children in Tikur Anbesa Specialized Hospital, Addis Ababa Ethiopia

“…In this study, the most common causes of bloodstream infections were gram-negative bacteria, in particular Klebsiella pneumoniae 31.4 % followed by Acinitobacter species 8.7% were the predominate among GNB isolates. This was supported by the study done in Jimma Ethiopia 31.4% [39],in African countries in Kenya 13% [ 40], Ghana 26% [41] , Bouaké, central Côte d'Ivoire 22.5% [42] in Asian such as in India by 25.8% ,30.5% [43,44] in Brazil, Latin America by Berezina et al [45], veitnam 20% [46] the most common isolate was Klebsiella pneumoniae. However it was inconsistent that the predominant GNB isolation rate varies from country to country where in India by Kante et al, [47], Indonesia by Murni et al, [48] frequently isolated pathogen in BSI was Pseudomonas other than Klebsiella pneumoniae in the same age group.…”