2017
DOI: 10.1111/cxo.12598
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Epidemiology of contact lens‐induced infiltrates: an updated review

Abstract: Corneal infiltrative events (CIEs) are well established as a risk associated with soft contact lens wear. The incidence of symptomatic CIEs during extended soft lens wear ranges from 2.5 to six per cent; when asymptomatic CIEs are included, the incidence can be as high as 20-25 per cent. In daily soft lens wear, the annual incidence of symptomatic CIEs is about three per cent. There are various accepted methods of categorising CIEs, and a scoring system based on clinical signs and symptoms is a good approach t… Show more

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Cited by 51 publications
(38 citation statements)
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“…A significantly lower proportion of cases with CIEs were wearing DD lenses, when compared with their matched controls (2% vs. 13 % controls), signifying that DD lenses were protective against the development of CIEs and reduced their risk by 75 %. A possible reason for this protective effect is that replacing a lens every day results in lower levels of bioburden on the lens and there is also no opportunity for contamination from the storage case [43,44]. In a subsequent study, CIE rates of 0.4 % for SiH DD and 0% for hydrogel DD contact lenses were reported, both of which were significantly lower than previously reported rates for reusable SCLs of 3%-4% per year, indicating improved ocular health outcomes with DD lenses [45].…”
Section: Benefits Of a Daily Disposable Modality: Convenience Physiomentioning
confidence: 99%
“…A significantly lower proportion of cases with CIEs were wearing DD lenses, when compared with their matched controls (2% vs. 13 % controls), signifying that DD lenses were protective against the development of CIEs and reduced their risk by 75 %. A possible reason for this protective effect is that replacing a lens every day results in lower levels of bioburden on the lens and there is also no opportunity for contamination from the storage case [43,44]. In a subsequent study, CIE rates of 0.4 % for SiH DD and 0% for hydrogel DD contact lenses were reported, both of which were significantly lower than previously reported rates for reusable SCLs of 3%-4% per year, indicating improved ocular health outcomes with DD lenses [45].…”
Section: Benefits Of a Daily Disposable Modality: Convenience Physiomentioning
confidence: 99%
“…This is not surprising since there is very strong evidence in the literature of the oxygen-related health benefits associated with SiH contact lens materials [10], and SiH daily disposable lenses have been recommended as the preferred option for daily wear [18]. The rates of inflammation and infection with re-usable SiH contact lenses have been reported to be higher than with their hydrogel counterparts, particularly when worn on an overnight basis [19][20][21]; however, the annualized incidence rates for corneal infiltrative events was reported to be only 0.4% with daily disposable SiH lenses in a large registry study [7] as compared with 3.3 to 10% per year with reusable soft contact lenses [22].…”
Section: Healthmentioning
confidence: 99%
“…The incidence of microbial keratitis is 2-4 per 10 000 for soft contact lens wearers, but is higher for extended or overnight contact lens wear78 (table 1). Other risk factors are listed in box 1 1012. The most common cause is Pseudomonas spp; however, Gram positive infection with Staphylococci and Streptococcus, and fungal and parasitic infections can also occur 10…”
Section: Approach In Primary Carementioning
confidence: 99%