Epidemiology of deep vein thrombosis

Wolf, Simon; Barco, Stefano; Di Nisio, Marcello; Mahan, Charles E.; Christodoulou, Konstantinos C.; ter Haar, Sophie; Konstantinides, Stavros; Kucher, Nils; Klok, Frederikus A.; Cannegieter, Suzanne C.; Valerio, Luca

doi:10.1024/0301-1526/a001145

Vasa

2024

DOI: 10.1024/0301-1526/a001145

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Epidemiology of deep vein thrombosis

Simon Wolf,

Stefano Barco,

Marcello Di Nisio

et al.

Abstract: Summary: Deep vein thrombosis (DVT) is a cause of considerable morbidity worldwide. It is a common clinical disease in the daily practice of several medical disciplines including general medicine, angiology, and internal medicine, as well as of interest to public health because of its preventability and its sensitivity to secular changes in the distribution of population risk factors. In this review we present a comprehensive overview of the epidemiological features of DVT, including incidence and risk factors… Show more

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Cited by 3 publications

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The Postthrombotic syndrome, where are we now?

Hupperetz,

Ten Cate-Hoek

2024

Vasa

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Summary: Post thrombotic syndrome (PTS) is a frequent complication occurring in patients with deep venous thrombosis (DVT). This chronic condition is associated with a negative impact on quality of life and substantial economic costs. Despite current treatment with anticoagulants and compression therapy, a significant proportion of DVT patients develop PTS. Optimising the diagnosis and identification of high-risk patients is important to provide more appropriate individualised treatment. In addition, a better understanding of the pathogenesis is leading to the necessary improvement of both current treatment strategies and the development of new treatment modalities. Treatments aimed at prevention as well as those aimed at reducing the symptoms of already manifested PTS should be further investigated. Research is currently taking place on promising therapeutical targets including pharmacological (anti-inflammatory and venoactive drugs), and interventional approaches (e.g. mechanical thrombectomy) in patients at different stages of PTS. Progress in all these areas is needed to solve the complex problem of PTS.

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The Postthrombotic syndrome, where are we now?

Hupperetz,

Ten Cate-Hoek

2024

Vasa

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Advances in the management of venous thromboembolism

Forgo,

Barco

2024

Vasa

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Venous Thromboembolism (VTE) in May-Thurner Syndrome: Decision-Making Related to Long-Term Anticoagulation

Krishnan,

Desai

2024

Cureus

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May-Thurner syndrome (MTS) involves the compression of the left iliac vein between the right iliac artery anteriorly and the lumbar vertebrae posteriorly. Patients may remain asymptomatic throughout their lives or experience unilateral lower limb swelling and symptoms of deep vein thrombosis (DVT), such as redness and pain in the limb, or features of its complication (pulmonary embolism) such as chest pain or shortness of breath. We present the case of a 34-year-old female exhibiting acute pain and tightness in her left leg, due to DVT of the left common femoral vein, extending up to the pelvic veins, which, on further diagnostic imaging, was found to be due to MTS. The patient was initiated on lifelong anticoagulation to prevent further complications. The rising incidence of MTS, coupled with frequent delays in its diagnosis, highlights the need to raise awareness among healthcare providers, especially acute medics (who are often the first point of contact for the patient) to expand their diagnostic umbrella of differentials to include MTS as a potential cause of such presentations and to look and think beyond DVT of the lower limb. This is especially important in females presenting with non-specific DVT symptoms, as early suspicion and referral to the respective medical teams including vascular medicine, can improve diagnostic accuracy and provide more management options, thereby improving long-term outcomes.

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Epidemiology of deep vein thrombosis

Cited by 3 publications

References 82 publications

The Postthrombotic syndrome, where are we now?

The Postthrombotic syndrome, where are we now?

Advances in the management of venous thromboembolism

Venous Thromboembolism (VTE) in May-Thurner Syndrome: Decision-Making Related to Long-Term Anticoagulation

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