Epidemiology of dermatomycoses in children in Northern Mato Grosso 2015‐2020

Correia, Neocimar Saraiva; Balbinot, Rayssa Tuanna Schmidt; Bonacorsi, Cibele; Donofrio, Fabiana Cristina

doi:10.1111/myc.13439

Cited by 4 publications

(1 citation statement)

References 38 publications

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“…Onychomycosis occurred as age-related infections. It is a rare pathology in infants (incidence less than 0.3%) and which constitutes 15.5% of onychodystrophies in children [1], especially those with Down syndrome and the immunocompromised [2]. The differential diagnosis arises with psoriasis, atopic dermatitis, lichen planus, ichthyosis.…”

Section: Introductionmentioning

confidence: 99%

Interest of Dermoscopy for the Diagnosis of Onychopathy in an Infant

Khabba

Asermouh²,

Ismaïli³

et al. 2023

AJPR

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Aim: Onychomycosis is a rare pathology in infants which constitutes 15.5% of onychodystrophies in children, especially those with Down syndrome and the immunocompromised. Dermosocpy is an innocuous examination allowing to guide the clinical diagnosis and to avoid invasive examinations. Presentation of Case: 5-month-old infant presents with thickening of the thumbnail of the left hand with xanthonychia evolving for 20 days without notion of trauma. On clinical examination, xantho-pachyonychia of the thumbnail of the left hand was noted reaching the latero-distal part with subungual hyperkeratosis and peronyxis. Dermoscopy showed yellowish chromonychia, longitudinal striae, subungual hyperkeratosis with jagged edges. The mycological direct examination and culture was in favor of a Candida albicans infection The patient was put on an antifungal cream with improvement after 3 months. Discussion: The rarity of onychomycosis in infants can be attributed to several factors such as the difference in the structure of the nail plate, less exposure to trauma and rapidity of nail regrowth. The average age is 8 months, the sex ratio at 0.98 and the preferential location is the fingernails. Clinically the nail involvement is of the disto-lateral type with subungual hyperkeratosis and peronyxis. Dermatoscopy is a quick tool showing chromonychia, longitudinal streaks, subungual hyperkeratosis producing a “ruined appearance”, distal onycholysis with jagged edges and linear hemorrhages. Infant onychomycosis is most often of candidal origin (C. albicans). Topical antifungals (ciclopirox) are preferred. Conclusion: This case is being reported to highlight the important role of dermoscopy in the diagnosis of onychomycosis and thus prevent unnecessary biopsies.

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Section: Introductionmentioning

confidence: 99%

Interest of Dermoscopy for the Diagnosis of Onychopathy in an Infant

Khabba

Asermouh²,

Ismaïli³

et al. 2023

AJPR

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Production of IgY against iron permease Ftr1 from Candida albicans and evaluation of its antifungal activity using Galleria mellonella as a model of systemic infection

Souza

Corrêa

Gameiro

et al. 2023

Microbial Pathogenesis

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DNA Sequencing Accurately Diagnosed 146 Cases of Superficial Mycosis

Wang,

Chen,

Yang

et al. 2024

IJIDT

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Objective: Traditional fungal detection methods, such as fungal microscopy and cultivation, often have drawbacks such as high false negative rates and time-consuming cultivation. Using molecular biology methods for diagnosis can not only be used for identifying fungal strains in cultured colonies, but also for diagnosing diseased tissues, which can shorten the diagnosis time. There is a lack of systematic research on the clinical characteristics, susceptibility factors, and the composition and distribution of pathogenic fungi of superficial mycosis in Shiyan area. In order to understand the relevant situation of superficial mycosis and pathogenic fungi in this area, this study conducted a molecular epidemiological investigation on 146 patients with superficial mycosis who visited our outpatient department. Methods: From January 2022 to December 2022, the typical clinical manifestations of outpatient visits in our department were collected. 146 cases of superficial fungal patients with positive fungal microscopy were cultured and DNA was extracted. PCR technology was applied to compare the products in GeneBank after the amplification of ITS region. Results: A total of 23 pathogenic strains were obtained, including 112 strains of Trichophyton rubrum (76.71%), 5 strains of other dermatophytes (3.42%), 6 strains of Candida species (4.11%), 4 strains of Aspergillus species (2.74%), 8 strains of Cladosporium species (5.48%), and 11 strains of other fungi (7.53%). Conclusions: DNA sequencing combined with traditional fungal microscopic culture is helpful for more accurate diagnosis of superficial mycosis.

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Epidemiology of dermatomycoses in children in Northern Mato Grosso 2015‐2020

Cited by 4 publications

References 38 publications

Interest of Dermoscopy for the Diagnosis of Onychopathy in an Infant

Interest of Dermoscopy for the Diagnosis of Onychopathy in an Infant

Production of IgY against iron permease Ftr1 from Candida albicans and evaluation of its antifungal activity using Galleria mellonella as a model of systemic infection

DNA Sequencing Accurately Diagnosed 146 Cases of Superficial Mycosis

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