Epidemiology of endometriosis in infertile women

Matorras, Roberto; Rodíquez, Fernando; Pijoán, José Ignacio; Ramón, Olga; Terán, Gloria Gutierrez de; Rodriguez-Escudero, F.J.

doi:10.1016/s0015-0282(16)57293-8

Cited by 93 publications

(57 citation statements)

References 19 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…This result seems interesting, in the light of a previous finding to the reports that the expression levels of AhR mRNA in blood were higher in smokers [31][32][33]. Epidemiologically, women who smoke have a reduced risk of endometriosis [34][35][36][37][38]. Though the causal relationship between smoking and AhR expression is unknown, different regulatory mechanisms for the expression of AhR might be working in blood and in the endometrium.…”

Section: Discussionsupporting

confidence: 51%

Expression of Ah Receptor and Dioxin-Related Genes in Human Uterine Endometrium in Women with or without Endometriosis.

et al. 1999

View full text Add to dashboard Cite

Abstract.2,3,7,8-Tetrachlorodibenzo p-dioxin (TCDD) has been suggested as a possible etiologic factor for endometriosis, a condition in which endometrium-like tissues are present outside the uterus. The prevailing view pertaining to the origin of endometriotic cells is that they are from eutopic endometrial cells which regurgitate through fallopian tubes. In order to get insight into the possible involvement of TCDD in the pathogenesis of endometriosis, we suspected that TCDD may act differently on the endometrium with or without endometriosis. To address this, we examined the presence of messenger RNAs of arylhydrocarbon receptor (AhR), AhR nuclear translocator (Arnt) and two dioxin-responsive genes, cytochrome P-450 1B1 (CYP1B1) and downstream of tyrosine kinases (p62(dok)), in the endometrium of women with or without endometriosis using semi-quantitative reverse transcription-polymerase chain reaction. All the genes were expressed throughout the menstrual cycle. The expression level of p62(dok) was higher in the proliferative phase than in the secretory phase. In contrast, the expression levels of AhR, Arnt and CYP 1 B 1 seemed to be constant during the cycle. In terms of the comparison between non-endometriosis and endometriosis group, the mRNA levels of AhR, Arnt, CYP 1 B 1 and p62(dok) were essentially similar. Interestingly, AhR mRNA level was significantly lower in smokers than in non-smokers.Based on the regression analysis, significant linear and positive correlations were observed between AhR and Arnt mRNA levels, and between Arnt and p62(dok) mRNA levels. In summary, expression of AhR and dioxin-related genes in the endometrium did not differ in women with or without endometriosis.

show abstract

Section: Discussionsupporting

confidence: 51%

Expression of Ah Receptor and Dioxin-Related Genes in Human Uterine Endometrium in Women with or without Endometriosis.

et al. 1999

View full text Add to dashboard Cite

show abstract

“…Parmi les femmes présentant une infertilité, l'endomé-triose est retrouvée dans 20 à 70 % des cas et 30 à 50 % des patientes atteintes d'endométriose sont infertiles [15]. La fécondité chez les patientes porteuses d'endomé-triose est de 2 à 10 % par mois contre 15 à 20 % par mois chez les patientes saines [1].…”

Section: Discussionunclassified

Fertilité après chirurgie cœlioscopique de l'endométriose pelvienne chez des patientes en échec de grossesse

Fuchs

Raynal

Salama

et al. 2007

Journal de Gynécologie Obstétrique et Biologie de la Reproducti

View full text Add to dashboard Cite

“…1 At present it is generally agreed that surgical treatment is the treatment of choice for infertile patients presenting with endometriosis. For patients presenting with moderate or severe endometriosis, the fertility result are better with surgical treatment than with no treatment or with medical treatment.…”

Section: Introductionmentioning

confidence: 99%