Epidemiology of fragility fractures in Sakaiminato, Japan: incidence, secular trends, and prognosis

Tsukutani, Y.; Hagino, Hiroshi; Ito, Yasuyo; Nagashima, Hideki

doi:10.1007/s00198-015-3124-z

Cited by 69 publications

(55 citation statements)

References 42 publications

(58 reference statements)

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“…The results of this study, which encompassed the entire Japanese population aged 65 years and older, closely match the results of the previous studies performed in restricted regions of Japan, [7][8][9][10] by prefecture or city unit that assessed data trends pertaining to: (1) the highest number of fractures, regardless of age cohort for older people, occurring in patients with vertebral fractures, and (2) the second highest number of fractures occurring in patients with distal radius fractures for the earlier older age cohorts and patients with femoral neck fractures for the later older age cohorts, which were exponentially increased. These similarities strengthen the validity of our study.…”

Section: Discussionsupporting

confidence: 89%

“…23) Second, for comorbidities, no attempt was made to improve the precision of the information by assessing modifier codes and any other examinations which could potentially introduce information bias. Third, we were not able to estimate the incidence rate of fractures or compare the incident rates in the previous regional studies performed inside [7][8][9][10] and outside 1,2,22) of Japan, because our data are derived from a polypharmacy study with a case-crossover design. In this study, fractures were recorded but there was no cohort of all older people in Japan who were relatively healthy, although that cohort is needed to calculate the incidence rate.…”

Section: Discussionmentioning

confidence: 99%

“…4) Fragility fractures caused by a slight external force, such as a fall from standing height or lower, due to age-related loss of bone density, 1,2,5,6) occur more frequently among older people. However, to the best of our knowledge, previous epidemiologic studies that have evaluated fragility fractures in the Japanese population [7][8][9][10] were conducted in discrete regions rather than nationally, and have not elucidated the proportion of patients hospitalized for fractures. To minimize medical costs in a nation whose older population is continuing to expand and live longer than previous generations, it is imperative to appropriately evaluate the health economy associated with fragility fractures and adapt the health policy in Japan accordingly.…”

Section: Introductionmentioning

confidence: 99%

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Fragility Fractures in Older People in Japan Based on the National Health Insurance Claims Database

Iihara

Ohara

Bando

et al. 2019

Biological & Pharmaceutical Bulletin

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Fragility fractures associated with age-related bone loss are of urgent concern worldwide because they reduce QOL and pose financial burdens for health care services. Currently, national data in Japan are limited. This study provides quantitative data for older patients throughout Japan who, although otherwise relatively healthy, sustained fragility fractures and were hospitalized for them. The National Database of Health Insurance Claims and Specific Health Checkups of Japan was accessed to target patients aged 65 years or older who sustained fractures between May 2013 and September 2014 and were not hospitalized for at least 13 months prior to fracture. We investigated whether the first fracture sustained was fragility related at any of four locations (proximal humerus, distal radius, vertebra, or femoral neck) and whether it necessitated hospitalization. Fragility fractures were identified in 490138 of 1188754 patients (41.2%, 345980 patients/ year; 1 : 4 male-to-female ratio). Regardless of gender, vertebral fractures were most common across the age cohorts studied (43286 males and 162767 females/year), and femoral neck fractures increased markedly with increased patient age. Approximately 80% of patients with femoral neck fractures were hospitalized (62.3% of males, 71.1% of females) compared with up to 10.4% of patients with other fragility fractures. Data provided in this study can be used as a baseline for evaluating the health economy and establishing health policy in Japan.

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Section: Discussionsupporting

confidence: 89%

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Fragility Fractures in Older People in Japan Based on the National Health Insurance Claims Database

Iihara

Ohara

Bando

et al. 2019

Biological & Pharmaceutical Bulletin

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“…3,32 To compare rates of DRF in different countries, Table 1 49,50 ) and Africa (Nigeria 51 , Cameroon 52 ). Within each region, the publications are presented in chronological order according to the study period.…”

Section: Epidemiologymentioning

confidence: 99%

Epidemiology of distal radius fractures and factors predicting risk and prognosis

MacIntyre

Dewan

2016

Journal of Hand Therapy

290

190

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“…In previous studies conducted in Europe, North America, and Asia, the overall incidence rates of distal radius fracture have been shown to increase over time [6][7][8]. Other more recent studies have shown no change, or even a decrease, in the incidence [9][10][11].…”

Section: Introductionmentioning

confidence: 99%

Incidence of distal radius fracture in a general population in southern Sweden in 2016 compared with 2001

et al. 2020

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In this population-based study, we compared the incidence of distal radius fracture in 2016 with that in the same region's adult general population in 2001 using radiographs to identify fracture cases. We showed that the incidence decreased by 24% in 2016 compared with 2001 indicating an important development.Introduction We conducted an epidemiological study on residents of northeastern Skåne in southern Sweden (population 182,000) to determine the overall incidence of distal radius fracture and the incidence according to age, sex, and fracture characteristics in the region's adult population during 2016, and to study the change in incidence in the same general population between 2001 and 2016 using wrist radiographs to identify fracture cases. Methods Two orthopedic surgeons examined all wrist radiographs performed at the only two emergency hospitals in the study region to identify individuals, above 18 years of age, who sustained fracture of the distal radius during 2016. We used Poisson regression analysis adjusting for age, sex, and at-risk population to compare the incidence in 2016 with the incidence in 2001, previously estimated using similar methodology. Results The overall incidence in 2016 was 22 (95% CI 20-25) per 10,000; the incidence in women was 34 (95% CI 30-39) and in men was 10 (95% CI 8-12) per 10,000. The overall incidence in 2016 was 0.76 (95% CI 0.70-0.82) of the incidence in 2001 (p < 0.0001). The incidence in the 3 age groups 19-49, 50-79, and ≥ 80 years was 0.91 (95% CI, 0.69-1.20), 0.67 (95% CI, 0.55-0.82), and 0.49 (95% CI, 0.25-0.97) of the incidence in 2001, respectively. Conclusion In a general population in Sweden, a statistically significant and clinically important decrease in the incidence of distal radius fracture occurred between 2001 and 2016, driven by lower incidence in individuals 50 years or older.

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Epidemiology of fragility fractures in Sakaiminato, Japan: incidence, secular trends, and prognosis

Cited by 69 publications

References 42 publications

Fragility Fractures in Older People in Japan Based on the National Health Insurance Claims Database

Fragility Fractures in Older People in Japan Based on the National Health Insurance Claims Database

Epidemiology of distal radius fractures and factors predicting risk and prognosis

Incidence of distal radius fracture in a general population in southern Sweden in 2016 compared with 2001

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