Epidemiology of hepatitis C in Islamic Republic of Iran

Afzali, Majid; Mirzaei, Masoud

doi:10.1016/s2222-1808(16)61166-0

Cited by 11 publications

(17 citation statements)

References 25 publications

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“…The source of the notification was clinical laboratory for more than half of the patients. These findings are consistent with those reported in the literature (7,12,13,14,15).…”

Section: Discussionsupporting

confidence: 94%

The Epidemiology and Trend of Hepatitis C Infection in Hamadan Province: West of Iran, 2011-2016

Khazaei¹,

Mofarrah-Zat²,

Nematollahi³

et al. 2018

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Objectives: Hepatitis C virus (HCV) is a blood-borne virus which is transmitted through the exposure to small amounts of blood. The objective of this study was to investigate trend and epidemiological pattern of hepatitis C infection during seven successive years in Hamadan province during 2011-2016. Materials and Methods: This cross sectional study was conducted on the new cases of HCV (n=803) who were recorded in the deputy of health of Hamadan University of Medical Sciences. The Cochran-Armitage test was used to investigate the changes in the trend of the disease according to various demographical and clinical characteristics. Incidence rates of HCV were estimated by district for 2016. Results: Totally, 705 (87.8%) cases were male and 98 (79.7%) were urban dwellers and the highest proportion of the cases (51%) belonged to the age group of 25-44 years. The overall incidence rate of HCV infection in Hamadan province was 5.26 per 100.000 in 2016, while the southern counties had higher incidence rate compared to the northern parts. Only 8.1% of cases were assessed due to clinical symptoms. Conclusion: Our results showed that HCV has a decreasing trend for both genders in Hamadan province and is most prevalent among males, age group of 25-44 years, married people and urban dwellers. Therefore, educational programs for the transmission and prevention of hepatitis C in the community and for high-risk groups should be conducted with the management of health centers and mass media.

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“…The source of the notification was clinical laboratory for more than half of the patients. These findings are consistent with those reported in the literature (7,12,13,14,15).…”

Section: Discussionsupporting

confidence: 94%

The Epidemiology and Trend of Hepatitis C Infection in Hamadan Province: West of Iran, 2011-2016

Khazaei¹,

Mofarrah-Zat²,

Nematollahi³

et al. 2018

vhd

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“…Chronic HBV may lead to cirrhosis, fibrosis and hepatocellular carcinoma ( 3 ) In Asia, the majority of HBV infections are acquired parentally or, in early childhood, through vertical (mother-to-child) transmission; however, horizontal transmission is the main route of infection in African and Western countries ( 2 ). The prevalence of HBV Infection among the different groups of patients was also reported in Iran ( 4 - 7 ). So far 10 HBV genotypes (A-J) and different sub-genotypes have been reported ( 8 ).…”

Section: Introductionmentioning

confidence: 80%

Occult Hepatitis B Virus Among the Patients With Abnormal Alanine Transaminase

Makvandi

Neisi

Khalafkhany

et al. 2014

Jundishapur J Microbiol

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Background:The occult hepatitis B infection (OBI) is defined as the presence of hepatitis B virus (HBV) DNA in the sera or in the liver biopsy and the absence of hepatitis B surface antigen (HBsAg) by serological test.Objectives:The current study aimed to evaluate the occult HBV infection by polymerase chain reaction (PCR) and determine HBV genotyping among the patients with abnormal alanine transaminase (ALT) in Ahvaz city, Iran.Patients and Methods:The sera of 120 patients, 54 (45%) females and 66 (55%) males, with abnormal ALT 40-152 IU were collected. All the patients were negative for HBsAg for more than one year. The patients` sera were tested by PCR using primers specified for the S region of HBV. Then the positive PCR products were sequenced to determine HBV genotyping and phylogenic tree.Results:Of these 120 subjects, 12 (10%) patients including 6 (5%) males and 6 (5%) females were found positive for HBV DNA by PCR, which indicated the presence of occult HBV infection among these patients. The sequencing results revealed that genotype D was predominant with sub-genotyping D1 among OBI patients.Conclusions:Occult hepatitis B infection is remarkably prevalent in Ahvaz, Iran, and should be considered as a potential risk factor for the transmission of Hepatitis B Virus throughout the community by the carriers.

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“…The province's outbreak ranged from 1.7% to 5% in Fars and Sistan and Baluchestan, respectively. In Tehran, HBV prevalence was 3.6% and 1.6% for males and females, respectively (8).…”

Section: Introductionmentioning

confidence: 99%

Prevalence of Hepatitis B Surface Antigen Among People Attending Medical Diagnostic Laboratories in Neyshabur, Northeast of Iran, During Years 2011 to 2015

Salehi

Najafi

2017

Arch Pediatr Infect Dis

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Background: Hepatitis B Virus (HBV) infection remains a public health and health care issue in Iran. Since the data on its outbreak is required for effectual policies, this epidemiological study was performed on population from Neyshabur, where there has been no former epidemiological information. Objectives: This study aimed at investigating the epidemiology of hepatitis B surface antigen among subjects from Neyshabur, from year 2011 to 2015. Methods: The researchers established this study from data collected from a surveillance system. Screening tests were carried out by the Chemioluminsance method. Age, gender, referral year and month were the investigated variables. Data were analyzed by the SPSS-20 software. Results: The prevalence of HBsAg in Neyshabur was 4.11%. In the age group of more than 40 years (1.87%) and females (2.2%) had significantly (P < 0.0001) higher rates of HBV seropositivity. Also the year 2011 (5.26%) and the month of July (0.48%) had the highest prevalence. Conclusions: Hepatitis B Virus (HBV) infection rate was seemingly high in Neyshabur, even higher than other parts of Iran. An immunization program should be continued progressively for high-risk areas, especially the Neyshabur city of Iran.

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Epidemiology of hepatitis C in Islamic Republic of Iran

Cited by 11 publications

References 25 publications

The Epidemiology and Trend of Hepatitis C Infection in Hamadan Province: West of Iran, 2011-2016

The Epidemiology and Trend of Hepatitis C Infection in Hamadan Province: West of Iran, 2011-2016

Occult Hepatitis B Virus Among the Patients With Abnormal Alanine Transaminase

Prevalence of Hepatitis B Surface Antigen Among People Attending Medical Diagnostic Laboratories in Neyshabur, Northeast of Iran, During Years 2011 to 2015

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