2In a recent study of elderly, rural-dwelling Tanzanians, the incorrect classification of more than a quarter of patients as hypertensive was attributed to the white-coat effect.1 Although the white-coat effect might contribute to the overestimation of the prevalence of hypertension (HTN), systolic blood pressure (SBP) variability is known to enhance cardiovascular (CV) risk. In addition, white-coat HTN is now regarded as an intermediate phenotype between normotension and HTN. On the other hand, relatively high nocturnal blood pressure (BP) resulted in nighttime HTN in more than two thirds of the cohort of elderly, rural-dwelling Tanzanians. SubSaharan Africans were already reported to have higher nighttime BPs than Caucasians with a blunted nocturnal decline, so that ambulatory BP monitoring (ABPM) might be especially useful in this ethnic group.As recently underlined by the Global Burden of Disease study, 2 HTN results in more deaths than any other risk factors, including diabetes and cigarette smoking. High prevalence, inadequate awareness, suboptimal treatment, and low rates of guideline-recommended target BP control are key factors that lead to severe CV complications that impose a heavy socioeconomic burden, especially in developing countries. A systematic review and meta-analysis 3 pooling data from 33 surveys published between 2000 and 2013, involving more than 110,414 participants with a mean age of 40 years, shows that in sub-Saharan Africa the predicted prevalence of HTN at mean participant ages of 30, 40, 50, and 60 years were 16%, 26%, 35%, and 44%, respectively, with a pooled prevalence of 30% (95% confidence interval [CI], 27-34). Most importantly, of those with HTN, only between 7% and 56% (pooled prevalence: 27%; 95% CI, 23-31) were aware of their hypertensive status before the surveys. Overall, 18% (95% CI, 14-22) of individuals with HTN were receiving treatment across the studies, and only 7% (95% CI, 5-8) had controlled BP.3 The HTN burden is likely to grow in the next few decades as the population ages and the prevalence of obesity and diabetes increases. These data clearly highlight the need for implementation of timely and appropriate strategies for diagnosis, control, and prevention.