Epidemiology of Lymphatic Filariasis

Jw, Mak

doi:10.1002/9780470513446.ch2

Cited by 27 publications

(32 citation statements)

References 7 publications

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“…[21] Histopathological findings of filariasis consists of distinct morphological features related to the presence of live or dead parasites associated with blockage and destruction of the lymphatic system. [22,23] A large proportion (56.3%) of filarial worms in this study were found within epididymal and/or paratesticular soft tissues or lymphatics, while the remaining were identified within the tunica vaginalis. Histological tissue reaction is minimal around live filariae, and almost all are found completely free within the lumen of a lymphatic vessel.…”

Section: Discussionmentioning

confidence: 65%

“…[24] Lethally injured adult worms may rupture their external membranes and eosinophils can be seen surrounding or attached to the adult worm cuticle. [23] A brightly eosinophilic Splendore-Hoeppli phenomenon may also be seen surrounding MF or adult worms. [24] In this study we also identified MF larvae within the tunica, surrounded by a dense fibrinopurulent inflammatory reaction.…”

Section: Discussionmentioning

confidence: 99%

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Clinicopathological Spectrum of Chronic Filarial Epididymo-Orchitis

Paul

Kwatra

Calton

et al. 2018

APALM

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Background: Filariasis is a vector-borne neglected tropical disease, most commonly caused by Wuchereria bancrofti. Chronic lymphatic filariasis in males usually presents as scrotal swelling with hydrocoele, although, a variety of other genital manifestations can also be seen. This study was undertaken to establish the clinicopathological spectrum of chronic filarial epididymo-orchitis (FEO) in a tertiary care institution in India.Methods: Cross-sectional observational study spanning a retrospective period of 17 years from 2000-2017.

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Section: Discussionmentioning

confidence: 65%

Section: Discussionmentioning

confidence: 99%

Clinicopathological Spectrum of Chronic Filarial Epididymo-Orchitis

Paul

Kwatra

Calton

et al. 2018

APALM

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“…The longevity of adult parasite varies from 5-18 years, 8,9 but a maximum lifespan up to 40 years has been reported 10 . The microfilariae (mF) are produced from ova in the uterus of the female worm and sheathed mF begin to appear in the peripheral blood six months to one year after infection 11 . The mF remains in the arterioles of the lungs during the day and emerge at night.…”

Section: Transmission Cycle Of Parasitementioning

confidence: 99%

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2015

IJPSR

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Lymphatic Filariasis (LF) is a major public health problem not only in India but also other developed countries. Filariasis is the disease which is caused by a group of filarial worms. It is transmitted by mosquitoes -Culex quinquefasciatus globally the most important vector. They cause high morbidity and mortality among humans. The proper management is needed for preventing the morbidity and mortality by laboratory diagnostic methods. Irreversible "elephantiasis" is the major clinical manifestation for LF. Diethylcarbamazine (DEC) is the drug of choice for treating lymphatic filariasis. Sequential gradient pump therapy and complete decongestive therapy (CDT) are some additional treatment for better therapeutic value.

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“…Primary lymphedema is a rare etiology affecting approximately 1 in every 6000 live US births 3 . Secondary lymphedema is the most common etiology of lymphedema in the US and abroad with over 90 million affected as a result of parasitic infection, lymphatic trauma, surgery, obesity, radiation therapy, and chronic venous insufficiency 4 .…”

Section: Introductionmentioning

confidence: 99%