Low gestational weight gain (GWG) and low mid-upper arm circumference (MUAC) are associated with adverse pregnancy outcomes. We aimed to assess the prevalence and determinants of low GWG and low MUAC among pregnant women in rural Zinder, Niger. A community-based survey was conducted among 1,384 pregnant women in the catchment areas of 18 integrated health centers in the region of Zinder, Niger. Weight and MUAC were measured during an in-home visit and again 1 month later, when haemoglobin concentration and micronutrient status were also assessed. The prevalence of low GWG was defined based on the 2009 United States Institute of Medicine (U.S. IOM) guidelines (<0.35 kg/week) and less than the third centile of the International Fetal and Newborn Growth Consortium for the 21st Century (INTERGROWTH-21st) standards. Factors associated with GWG and MUAC were identified using logistic regression models adjusting for season, village, and gestational age. The median (interquartile range) age was 25.0 (20.7, 30.0) years, and 16.4% were ≤19 years. The prevalence of low GWG were 62.9% and 27.5% according to 2009 IOM and less than the third INTERGROWTH-21st centile, respectively; 24.9% had low MUAC. Higher α-1-acid glycoprotein (OR = 1.7, 95% CI [1.1, 2.8]) and C-reactive protein (OR = 1.2, 95% CI [1.02, 1.50]) increased the odds of low GWG. Adolescents (OR = 2.7, 95% CI [1.8, 4.0]), housewives (OR = 1.97, 95% CI [1.36, 2.86]), and those who reported recent food assistance (OR = 1.80, 95% CI [1.04, 3.11]) had higher odds of low MUAC. Prevalence of low GWG and low MUAC was high among pregnant women. Determinants of GWG and MUAC included socioeconomic, demographic, and biological factors, although only markers of inflammation were consistent predictors across different definitions of low GWG. This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited. 1 of 15 2 of 15 OUÉDRAOGO ET AL. bs_bs_banner The prevalence of low GWG was high among pregnant women in the Zinder region of Niger, and the odds of low GWG were consistently associated with higher concentrations of markers of inflammation (AGP and CRP). A considerable proportion of pregnant women also had low MUAC. Considering the importance of adequate GWG and MUAC for maternal health and pregnancy outcomes, effective and cost-effective interventions (e.g., daily iron folic acid supplementation; Baltussen, Knai, & Sharan, 2004, behaviour change communication about nutrition; Lamstein et al., 2014, and balanced protein energy dietary supplementation; Imdad & Bhutta, 2012) to ensure adequate GWG and nutritional status should be considered.
ACKNOWLEDGMENTSWe would like to thank the NiMaNu study team, the participants, the local communities, staff of the Zinder and Mirriah health districts, and the national steering committee. Our sincere appreciation goes to Pro-The authors declare that they have no conflicts of interest.
CONTRIBUTIONSThe ...