Epidemiology of meningiomas. A nationwide study of surgically treated tumours on French medico-administrative data

Champeaux, Charles; Weller, Joconde; Katsahian, Sandrine

doi:10.1016/j.canep.2018.11.004

Cited by 38 publications

(39 citation statements)

References 26 publications

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“…More females than males develop cranial meningiomas, with ratios varying from 1.08:1 to 2.4:1 to 3:1 [Table 2]. [3,6,10] The average age for all patients undergoing cranial surgery for meningiomas ranged from 49.6 – 64 years of age; males were typically in their fifties (average age 57.6), while females were usually in their late fifties/early sixties (average age 59.5) [Table 2]. [3,6,10]…”

Section: Introductionmentioning

confidence: 99%

“…Cranial meningiomas occur in multiple locations [Tables 1, 2]. [3,4,6,9,10] Colombo et al . (2009) performed…”

Section: Introductionmentioning

confidence: 99%

“…(2019) evaluated the French database (Programme de Medicalization des Systèmes d’Information (PMSI)) that included 25,737 surgically managed meningiomas (2008-2016: equivalent to 4.5/100, 000 persons/year), the majority were located on the convexity or in the middle fossa/skull base [Table 2]. [3]…”

Section: Introductionmentioning

confidence: 99%

“…The vast majority of cranial meningiomas are pathologically confirmed to be benign [Tables 1, 2]. [3,7,9] Following open surgical resection of 163 cranial meningiomas. Morokoff et al .…”

Section: Introductionmentioning

confidence: 99%

“…(2019) evaluated 25,737 surgically confirmed cranial meningiomas predominantly involving the convexity or middle skull base, 91.3% were benign lesions, 6.2% were atypical or of uncertain pathology, while 2.5% were malignant [Table 2]. [3]…”

Section: Introductionmentioning

confidence: 99%

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Review of Treatment Options for Smaller Benign Cranial Meningiomas: Observation, Stereotactic Radiosurgery, and Rarely, Open Surgery

Epstein¹

2019

Surgical Neurology International

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Background: MR/CT documented smaller cranial meningiomas in asymptomatic patients are often followed for years without requiring any intervention. Only a subset of patients who become symptomatic attributed to significant tumor growth, edema and/or mass effect may require stereotactic radiosurgery (SRS), and rarely, open surgery. Clearly, the decision for choosing any treatment modality must be made on a case by case basis and include an analysis of risks vs. benefits to the individual patient. Methods: Patients with smaller benign asymptomatic meningiomas are followed with sequential MR studies that typically document lack of tumor progression, edema, or mass effect. Those who become symptomatic with the typical triad (i.e. headaches, seizures, or visual loss) and other focal neurological deficits may warrant SRS, and only occasionally, open surgery. Surgery may indeed be warranted in the presence of certain mitigating factors, (e.g. young age, lesions located adjacent to by not yet invading critical structures etc.). Results: This review focused largely on smaller benign asymptomatic meningiomas. The non-operative/ conservative management vs. use of SRS vs. open surgery in select cases are discussed, along with a review of the morbidity/mortality of the respective interventions. Conclusion: There are multiple treatment options for patients with smaller asymptomatic cranial meningiomas. SRS may be warranted for those who exhibit tumor growth, increasing edema, and/or mass effect. Only rarely is open operative intervention necessary; this must include consideration of other factors that may warrant early surgery. Notably, the 5-year survival rates for SRS ranged from 95.2% - 97%, while the 10-year survival rates varied from 88.6% - 94%.

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Section: Introductionmentioning

confidence: 99%

“…Cranial meningiomas occur in multiple locations [Tables 1, 2]. [3,4,6,9,10] Colombo et al . (2009) performed…”

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

“…The vast majority of cranial meningiomas are pathologically confirmed to be benign [Tables 1, 2]. [3,7,9] Following open surgical resection of 163 cranial meningiomas. Morokoff et al .…”

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 3 more Smart Citations