Epidemiology of neural tube defect subtypes in Tunisia, 1991–2011

Nasri, Kaouther; Fradj, Mohamed Kacem Ben; Hamdi, Thouraya; Aloui, Mariem; Jemaa, Nadia Ben; Nahdi, Saber; Guesmi, Refka; Masmoudi, Aïda; Elmay, Michèle Véronique; Marrakchi, Raja; Gaigi, Soumeya Siala

doi:10.1016/j.prp.2014.06.027

Cited by 28 publications

(35 citation statements)

References 16 publications

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“…In our previous study (Nasri et al, ), we found a significant increase in the prevalence of NTDs cases during the 20‐year period (1991–2011), with a minimum incidence marked in 1991 with 0.57 births per 10,000 births and a maximum in 2009 with 3.47 births per 10,000 births. The median prevalence was 2.03 (±0.87) per 10,000 births.…”

Section: Introductionmentioning

confidence: 57%

Association of maternal homocysteine and vitamins status with the risk of neural tube defects in Tunisia: A case–control study

Nasri

Fradj²,

Touati

et al. 2015

Birth Defects Research

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Section: Introductionmentioning

confidence: 57%

Association of maternal homocysteine and vitamins status with the risk of neural tube defects in Tunisia: A case–control study

Nasri

Fradj²,

Touati

et al. 2015

Birth Defects Research

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“…In Canada, the prevalence was 8.6 per 10,000 births during 1999 to 2003 (De Wals et al, ). Other developed countries, for example, Germany (2.02/10,000 in 2011) (Nasri et al, ) and England and Wales (3/10,000 in 2004) (Morris and Wald, ) had lower prevalence, and Western Australia had higher prevalence (14.1/10,000 in 1996–2006) (Bower et al, ). All of these figures are much lower than the rate we observed in the present population.…”

Section: Discussionmentioning

confidence: 99%

Prevalence and trend of neural tube defects in five counties in Shanxi province of Northern China, 2000 to 2014

Liu

Zhang

et al. 2016

Birth Defects Research

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“…The prevalence of congenital anomalies according to literature data ranges from as low as 1.07% in Japan and as high as 4.3% in Taiwan 8,9 . Major anomalies, which significantly affect the development and quality of life of a human individual, are present in 2%-3% of newborn children, while another 2%-3% of malformations are diagnosed by the age of five 10,11 . They are one of the main causes of childhood deaths (up to 20%-25% of cases).…”

Section: Discussionmentioning

confidence: 99%

Congenital anomalies: Occurrence and potential risk factors

et al. 2020

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Background/Aim. Congenital malformations still represent one of the most important causes of prenatal and infant death.The study aim was to analyze occurrence, outcomes and risk factors of different types of congenital anomalies. Methods. The study included all pregnant women directed to Clinic of Obstetrics and Gynecology, Clinical Center of Serbia, Belgrade due to prenatally diagnosed congenital fetal anomalies during past ten years (January 1, 2008-December 31, 2017. Upon admission to our Clinic a detailed general medical and obstetrical history were taken from every patient. All women underwent genetic testing. Ultrasonography and magnetic resonance were diagnostic methods for fetal malformations confirmation. Results. The study included 773 pregnant women aged from 18 to 46 years. Out of registered nine different groups of fetal anomalies/malformations, the most common were malformations of the central nervous system, while majority of fetuses had combined multiple anomalies. Genetic cause for congenital anomalies was present in 25.2% of pregnancies. Medical preg-nancy abortion was performed in 71.8% of cases. Only 10.2% of pregnancies ended in term. The best outcome for children was obtained in case of gastrointestinal anomalies (52% live born). Contrary, only one child with neck and thorax malformations could be saved. According to logistic regression the most important predictor of having a child with combined multiple anomalies was mother's age, while predictor of central nervous system anomalies was gestational diabetes. The significant predictor of genetic anomalies was mother's age. Conclusion. In our sample neurological congenital anomalies were the most common, although abnormalities of all organ systems were registered. Majority of pregnancies had to be discontinued due to combined multiple anomalies caused by genetic disorders. Older mother's age and diabetes can imply on the increased risk for fetal malformations. ApstraktUvod/Cilj. Urođene malformacije i dalje predstavljaju jedan od najvažnijih uzroka prenatalne i neonatalne smrti. Cilj rada bio je analiza pojave ishoda različitih tipova kongenitalnih anomalija. Metode. Studijom su bile obuhvaćene sve trudnice koje su u periodu 1. januar 2008-31. decembar 2017. godine bile upućene na Kliniku za ginekologiju i akušerstvo Kliničkog centra Srbije zbog prenatalno dijagnostikovanih kongenitalnih fetalnih anomalija. Po prijemu na našu Kliniku uzimani su detaljni opšti medicinski i akušerski podaci od svake pacijentkinje. Sve trudnice su podvrgnute genetskom testiranju. Ultrazvuk i magnetna rezonanca su bili dijagnostičke metode za potvrdu malformacija fetusa. Rezultati. Studijom su obuhvaćene 773 trudnice koje su imale od 18 do 46 godina života. Od registrovanih devet različitih grupa fetalnih anomalija/malformacija, najčešcće su bile malformacije centralnog nervnog sistema, dok je vecína fetusa imala više kombinovanih anomalija. Genetički uzrok kongenitalnih anomalija bio je prisutan u 25,2% trudno-ća. Medicinski prekid trudnocće obavljen je u 71,8% ...

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Epidemiology of neural tube defect subtypes in Tunisia, 1991–2011

Cited by 28 publications

References 16 publications

Association of maternal homocysteine and vitamins status with the risk of neural tube defects in Tunisia: A case–control study

Association of maternal homocysteine and vitamins status with the risk of neural tube defects in Tunisia: A case–control study

Prevalence and trend of neural tube defects in five counties in Shanxi province of Northern China, 2000 to 2014

Congenital anomalies: Occurrence and potential risk factors

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