Epidemiology of Pediatric Brain Tumor in the Center of Referral Hospital in North Sumatera from 2013 -2017

Abstract

Brain tumors are the most common disease group of solid tumors in childhood, and children with brain tumors have a relatively poor survival rate. Epidemiologic data from a hospital-based registry provide the necessary information to obtain a full picture of the frequency of this disease, which is a great challenge in pediatric oncology. One hundred thirty four tumors in children between 0 and 17 years of age diagnosed between 2013 to 2017 were classified according the sex, and topography. Incidence of brain tumor in boys were higher than girls. From the registry data, the prevalence for boys was higher (67%). In the whole series, 54% were supratentorial, 46% infratentorial. The most common histopathologic pattern seen in the registry were pilocytic astrocytoma which accounts for 42 cases (31%) followed by medulloblastoma and craniopharygioma with the percentage of 25% and 18% respectively. The least histopathologic pattern of pediatric tumor seen in our center are diffuse astrocytoma and choroid plexus papiloma which was only seen in 1 patient for the last 5 years of our experience.

The Indonesian Central Nervous System Tumors Registry (Ina-CTR) : 7 years result from single institution of primary brain tumor epidemiology

“…(Figure 10). [15][16][17][18] One of the highlights is the number of glioblastomas in the author's data is quite low (4.2%) and almost similar to the data in Korea (5.3%), but the rate of glioblastoma is very high in the US, where based on CBTRUS 2011-2015, the prevalence rate of glioblastoma reaches 14.7%. Need to be further studied what factors cause the prevalence of glioblastoma prevalence in Asia and America.…”

“…In other hospitals in Bandar Lampung City with the percentage of women equal to 65% and males by 35%, and studies in the pediatric population at Adam Malik Hospital Medan with a percentage of 67% women and 33% men, while different results were reported from epidemiological studies in 10 hospitals in North Sumatra Province , a smaller percentage of women is 49.3% and men with a percentage of 50.7%. [15][16][17][18] This difference can be attributed to the time of observation carried out for 4 months while other studies conducted over a period of 12 months.…”

Characteristics of Neurological Deficits in Intracranial Tumors: A Literature Review

“…Brain tumors, known as intracranial tumors, are masses of abnormal tissue in which cells grow and reproduce uncontrollably, apparently uncontrolled by the mechanisms that control normal cells. More than 150 different brain tumors have been documented, but the two main groups of brain tumors are called primary and metastatic or secondary [39]. Primary brain tumors are brain tumors that develop from the brain cells themselves, whereas Secondary brain tumors are brain tumors that are secondary or metastasize from tumors in other bodies.…”

“…Metastatic tumors are considered cancerous and malignant [39]. Intracranial tumors are generally classified as malignant or benign.…”

“…Among children aged 10 to 19 years, the incidence of cerebellar and brain tumors is decreasing, while cerebral malignancies are increasing. In adults, the most common location by far is the cerebrum [39]. The incidence of primary brain tumors varies with age, gender, and ethnic origin.…”