Epidemiology of pertussis in a country with high vaccination coverage

Crespo, Inma; Cardeñosa, Neus; Godoy, Pere; Carmona, Glòria; Sala, M.; Barrabeig, Irene; Álvarez, Jaime; Minguel, Sofia; Camps, Neus; Caylà, Joan A.; Batalla, J.; Codina, Gemma; Domı́nguez, Àngela

doi:10.1016/j.vaccine.2011.03.065

Cited by 30 publications

(23 citation statements)

References 19 publications

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“…Although there are studies related to exemption requirements from immunization in school children and their associations with geographic clustering of infection (Crespo et al, 2011), no other study in Spain has focused on the detection of whooping cough clusters.…”

Section: Discussionmentioning

confidence: 99%

Retrospective space-time cluster analysis of whooping cough re-emergence in Barcelona, Spain, 2000-2011

et al. 2014

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Abstract.A retrospective, space-time study of whooping cough cases reported to the Public Health Agency of Barcelona, Spain between the years 2000 and 2011 is presented. It is based on 633 individual whooping cough cases and the 2006 population census from the Spanish National Statistics Institute, stratified by age and sex at the census tract level. Cluster identification was attempted using space-time scan statistic assuming a Poisson distribution and restricting temporal extent to 7 days and spatial distance to 500 m. Statistical calculations were performed with Stata 11 and SatScan and mapping was performed with ArcGis 10.0. Only clusters showing statistical significance (P <0.05) were mapped. The most likely cluster identified included five census tracts located in three neighbourhoods in central Barcelona during the week from 17 to 23 August 2011. This cluster included five cases compared with the expected level of 0.0021 (relative risk = 2436, P <0.001). In addition, 11 secondary significant space-time clusters were detected with secondary clusters occurring at different times and localizations. Spatial statistics is felt to be useful by complementing epidemiological surveillance systems through visualizing excess in the number of cases in space and time and thus increase the possibility of identifying outbreaks not reported by the surveillance system.

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Section: Discussionmentioning

confidence: 99%

Retrospective space-time cluster analysis of whooping cough re-emergence in Barcelona, Spain, 2000-2011

et al. 2014

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“…In locations with low vaccination coverage, circulation of B. pertussis in the community accounts for natural "boost". However, vaccination leads to a reduction in bacterial circulation and a subsequent loss of protection after natural infection, resulting in an increase in the incidence of the disease among teenagers and young adults, who become an significant source of infection of children 29,30,31,32,33,34,35,36,37,38,39,40 .…”

Section: Pertussis Vaccinesmentioning

confidence: 99%

“…The inclusion of the acellular pertussis vaccine is due to an increase in the incidence of pertussis in certain European countries 28,29,30,31,32,33,34,35,36,37,38,39,40 , the USA 1,78,9,10,11,12,21,24,25,26,27 , Canada 13,22,23 and Australia 16,17,41,42,43 . In these regions pertussis currently affects all age groups, and incidence rates are particularly high in adolescents and young adults 36,38,43 .…”

Section: Vaccine Recommendations For Hcpsmentioning

confidence: 99%

“…The availability of new diagnostic resources for pertussis, such as PCR and serology, has helped to identify pertussis as one of the main causes of prolonged cough illness in adults 22 and has shown that the disease may exist in mild or asymptomatic forms 33,51 . The large majority of pertussis cases are reported in young babies, but the disease may affect people of any age group, including the elderly 28,39,34,35,37,41,45,47,50,51,56 .…”

Section: Country Recommendationmentioning

confidence: 99%

“…However, HCP vaccination policies vary considerably between different countries 3,4,5,6,7,8,9,10,11,12,13,14,15,16,17,18,19 and have changed over the two last decades due to new information on the epidemiological profile of pertussis and licensing of new safe and effective vaccines for use in adolescents and adults, such as the triple acellular (Tdap) vaccine that, besides protecting against diphtheria and tetanus, also protects against pertussis, and the quadruple vaccine against diphtheria, tetanus and pertussis combined with the inactivated polio vaccine (Tdap-IPV), already licensed in a number of countries 7,8,9,10,11,12,20,21,22,23,24,25,26,27,28,29,30,31,32,33,34,35,36,37,38,39,40,41,42,43,…”

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Should acellular pertussis vaccine be recommended to healthcare professionals?

Moraes¹,

Carvalhanas

Bricks³

2013

Cad. Saúde Pública

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The aim of this study was to describe recent changes in the epidemiology of pertussis and existing policies regarding recommended and mandatory occupational vaccinations for healthcare professionals (HCPs). The authors carried out an extensive review of references on the PubMed and SciELO databases and the official sites of the World Health Organization, Pan American Health Organization, Centers for Disease Control and Prevention, and Brazilian Ministry of Health, using the keywords pertussis, vaccines and healthcare professionals. Vaccination against pertussis is recommended for HCPs in the United States, Canada, nine European countries, Australia, Hong Kong, Singapore, Costa Rica, Argentina and Uruguay, and in some countries it is compulsory. In Brazil, only one publication discussing the risk of pertussis among HCPs was found. Considering the reemergence of pertussis and the great number of associated hospitalizations and deaths registered in 2011, it is necessary to review public policies regarding HCP pertussis vaccination, particularly among workers in frequent contact with young babies.

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Commentary on ‘Antibiotics for whooping cough (pertussis)’

Shakib

2012

Evid.‐Based Child Health

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This is a commentary of Cochrane review, published in this issue of EBCH, first published as: Altunaiji SM, Kukuruzovic RH, Curtis NC, Massie J. Antibiotics for whooping cough (pertussis). Cochrane Database of Systematic Reviews 2007, Issue 3. Art. No.: CD004404. DOI: 10.1002/14651858.CD004404.pub3.Further information for this Cochrane review is available in this issue of EBCH in the accompanying Summary article. Copyright © 2012 The Cochrane Collaboration. Published by John Wiley & Sons, Ltd. The Cochrane Collaboration

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Epidemiology of pertussis in a country with high vaccination coverage

Cited by 30 publications

References 19 publications

Retrospective space-time cluster analysis of whooping cough re-emergence in Barcelona, Spain, 2000-2011

Retrospective space-time cluster analysis of whooping cough re-emergence in Barcelona, Spain, 2000-2011

Should acellular pertussis vaccine be recommended to healthcare professionals?

Commentary on ‘Antibiotics for whooping cough (pertussis)’

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