Epidemiology of Single-Unit Transfusion

Reece, Richard L.; Beckett, Ronald S.

doi:10.1001/jama.1966.03100100053014

Cited by 22 publications

(8 citation statements)

References 14 publications

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“…The use of single-unit transfusions has long been questioned; in an audit in 1965-1966, two-thirds ofthese were judged to be unnecessary. 15,16 However, in patients requiring red cells, transfusion of a single unit is preferable to transfusion of multiple units.s…”

Section: Red-cell Transfusionsmentioning

confidence: 99%

Appropriateness of transfusions of red cells, platelets and fresh frozen plasma

Metz

McGrath

Copperchini

et al. 1995

Medical Journal of Australia

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Objective: To determine how current hospital practice for transfusions of red cells, platelets and fresh frozen plasma conformed with published criteria. Design: Elaboration of criteria for transfusion from a review of the current literature; and analysis of the medical records of patients receiving transfusions of red cells (200), platelets (215), and fresh frozen plasma (260) during defined time periods in 1993. Setting: A large tertiary care teaching hospital. Outcome measures: Inappropriateness rates for transfusion episodes and numbers of individual units of blood products administered. Results: Inappropriateness rates for transfusion episodes and numbers of individual units administered were 16% and 10% for red cells, 13% and 11% for platelets, and 24% and 16% for fresh frozen plasma (31 % and 21% when transfusions for thrombotic thrombocytopenic purpura were excluded). Red cells and fresh frozen plasma were used inappropriately most frequently in association with a surgical procedure; for platelets, it was their use for bleeding. In many of the transfusions deemed inappropriate, deficiencie of red cells, platelets and/or coagulation factors were documented, but the degree of deficiency did not meet the stringent appropriateness criteria. Twentysix transfusions were deemed inappropriate because the indication was not documented in the medical record. Conclusions: Specific problem areas in which blood product use was inappropriate were identified. Guidelines for transfusion appropriateness, education of hospital staff, and a monitoring system to ensure adherence to the guidelines, are required.

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Section: Red-cell Transfusionsmentioning

confidence: 99%

Appropriateness of transfusions of red cells, platelets and fresh frozen plasma

Metz

McGrath

Copperchini

et al. 1995

Medical Journal of Australia

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“…Reviews of the epidemiology of RBC transfusion are available that examine larger populations and focus on specific diseases or surgical interventions. [18][19][20] In contrast, this study crosses all categories of recipients of allogeneic transfusions. The gender distribution for RBC transfusion has been reported by various investigators beginning in 1966.…”

Section: Discussionmentioning

confidence: 99%

Single Unit Transfusions in a Community Medical Center

O'Connor

Snowberger

2015

Clin Lab Sci

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Academic medical centers have implemented comprehensive patient blood management programs to reduce potential adverse transfusion effects. A retrospective study of single unit transfusions was conducted at a 319 bed community medical center to determine single unit transfusion practice patterns. Patient records of 535 single unit recipients were examined for gender, age and change in hemoglobin and hematocrit. Females (mean age 67) accounted for 64 % of recipients, with a mean increase in hemoglobin of 1.3 g/dL. Males (mean age 67) had a mean increase of 0.9 g/dL. An incidental finding was that laboratory assessment of hemoglobin was unavailable for 6% (pre transfusion) and 15% (post transfusion) of recipients. The proportion of single units transfused on a monthly basis ranged from 0.02% to 0.05%. No change toward increased use of single unit transfusion was identified. A formal patient blood management program is recommended as a next step in providing appropriate transfusion therapy.

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“…In the past many countries regarded single unit transfusions as a bad practice. [39] In the 1980s and early 1990s hospital based transfusion committees reviewed single unit transfusions. To prevent transfusion audits clinicians started ordering two units and hence clinical practice is now dominated with two unit transfusions.…”

Section: Discussionmentioning

confidence: 99%

“…This question has been raised again and again and the literature reports have expressed controversial opinions. [1–3] A Single unit of red blood cells transfusion can increase Hb by approximately 1 to 1.5 g in a 70 kg adult, which is therapeutically insignificant rise. [14] Moreover considering the risks associated with transfusion it is beneficial to prevent such transfusions.…”

mentioning

confidence: 99%

Evaluation of single unit red cell transfusions given to adults during surgery

Gupte

2007

Asian J Transfus Sci

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Background and objective:The ready availability of blood in Surat city has resulted in its liberal use. Surat Raktadan Kendra and Research Centre (SRKRC) is 30 years old blood bank having license to supply blood components. In spite of publishing quarterly bulletin and organizing seminars to update clinicians’ knowledge still we have not achieved rational use of blood. Present study has evaluated the use of single unit as well as whole blood transfusion for adult surgery cases.Materials and Methods:A total of 8470 surgery cases in the age group of 19 years to 95 years receiving 13070 units of whole blood and 3761 units of red cell concentrate (RCC) during surgery were analyzed on the basis of incidence of single unit and whole blood transfusions, sex and Hb values using Microsoft Excel.Results:Analysis revealed that 38.9% cases received single unit and 77.7% whole blood transfusions. Females more frequently received single unit transfusion than males (p< 0.001). The highest incidence of single unit (62.2%) and whole blood transfusion (95.2%) was observed for urogenital surgeries. The lowest incidence (22.9%) of single unit transfusion was for cancer surgeries. There was no significant difference in the mean Hb level at which male and female cases, received single unit transfusion (p>0.5). Mean Hb concentration was about 10.0 g/dl for patients receiving single unit of whole blood and 8 g/dl for those who received single unit of RCC.Conclusion:Surgery patients are receiving inappropriate transfusions. Continuous awareness programmes are needed to achieve judicious use of blood.

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Epidemiology of Single-Unit Transfusion

Cited by 22 publications

References 14 publications

Appropriateness of transfusions of red cells, platelets and fresh frozen plasma

Appropriateness of transfusions of red cells, platelets and fresh frozen plasma

Single Unit Transfusions in a Community Medical Center

Evaluation of single unit red cell transfusions given to adults during surgery

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