Epidemiology of sleep disorders in patients with chronic renal disease in Cairo, Egypt

Ibrahim, Juliani; Wegdan, Omar M.

doi:10.1097/01.epx.0000399136.00486.4e

Cited by 14 publications

(11 citation statements)

References 25 publications

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“…[ 15 16 ] Regionally, the prevalence of OSA symptoms among Egyptian hemodialysis (HD) patients was reported as 21-32%. [ 17 18 ] However, a cross-sectional study in two dialysis centers of Saudi Arabia was the only one published thus far on the prevalence of OSA in Saudi ESRD patients, as defined by the Berlin questionnaire. [ 19 ] The study yielded an extremely high overall prevalence of OSA risk, at 70% (males, 69%; females, 73.3%).…”

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confidence: 99%

Risk of obstructive sleep apnea among Saudis with chronic renal failure on hemodialysis

Wali¹,

Alkhouli²,

Howladar³

et al. 2015

Ann Thorac Med

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AIM:The prevalence of obstructive sleep apnea (OSA) in end-stage renal disease (ESRD) patients was reported to be 10-fold that in the general population. OSA can worsen the clinical symptoms and cardiovascular complications of ESRD. We aimed to investigate the prevalence of symptoms and risk of OSA among Saudi patients with ESRD.SETTINGS AND DESIGN:This multi-center, cross-sectional study was conducted in Jeddah, Saudi Arabia, between June 2012 and September 2013.METHODS:The prevalence of OSA was assessed using the Berlin questionnaire. The presence of daytime sleepiness was evaluated using the Epworth sleepiness scale. Data were also collected on the medical history, clinical, and laboratory findings of participants.RESULTS:In all, 355 patients (61% male) were enrolled (mean age: 45.5 ± 15.4 years). The overall prevalence of high-risk of OSA was 44.2% (males, 47.3%; females, 44.8%; P = 0.65). The prevalence of excessive daytime sleepiness (EDS) was 74%. Controlling for age, gender and body mass index, multivariate analysis revealed that hypertension and hepatitis C infection were the only comorbidities significantly associated with OSA (odds ratio [OR]: 3.827 and 0.559; confidence interval [CI]: 2.120-6.906 and 0.324-0.964; P < 0.0001 and 0.036, respectively). OSA was also strongly associated with EDS (OR: 3.054; CI: 1.676-5.565; P < 0.0001).CONCLUSIONS:In Saudi Arabia, the risk of OSA is more common in ESRD patients than in the general population. OSA is strongly associated with EDS. Interestingly, a significant negative correlation between OSA and hepatitis C infection was noted, which warrants further investigation.

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confidence: 99%

Risk of obstructive sleep apnea among Saudis with chronic renal failure on hemodialysis

Wali¹,

Alkhouli²,

Howladar³

et al. 2015

Ann Thorac Med

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“… 9 , 10 Several studies have evaluated the effects of kidney disease on sleep disturbances and sleep disorders upon escalating to CKD or ESRD status. 9 – 15 Though the reported data from these studies fluctuated widely in type (i.e. subjective vs. objective) of the parameter described, these studies mostly concurred that a direct linear relationship (correlation) exists between CKD or ESRD and insomnia.…”

Section: Introductionmentioning

confidence: 95%

“…Specifically, worsening CKD or ESRD correlated directly with worsening insomnia as defined by the full gamut of the sleep cycle to include but not limited to sleep onset and duration of sleep. 9 – 15 …”

Section: Introductionmentioning

confidence: 99%

Exploring sleep disorders in patients with chronic kidney disease

Nigam

Camacho

Chang

et al. 2018

NSS

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Kidney disorders have been associated with a variety of sleep-related disorders. Therefore, researchers are placing greater emphasis on finding the role of chronic kidney disease (CKD) in the development of obstructive sleep apnea and restless legs syndrome. Unfortunately, the presence of other sleep-related disorders with CKDs and non-CKDs has not been investigated with the same clinical rigor. Recent studies have revealed that myriad of sleep disorders are associated with CKDs. Furthermore, there are a few non-CKD-related disorders that are associated with sleep disorders. In this narrative review, we provide a balanced view of the spectrum of sleep disorders (as identified in International Classification of Sleep disorders-3) related to different types of renal disorders prominently including but not exclusively limited to CKD.

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“…133 and 14 studies of insomnia (prevalence 60.8%). 108,110,113,120,[134][135][136][137][138][139][140][141][142][143] Severity was reported variably.…”

Section: The Value Of Estimating Prognosis In Ckdmentioning

confidence: 99%

Executive summary of the KDIGO Controversies Conference on Supportive Care in Chronic Kidney Disease: developing a roadmap to improving quality care

Davison

Levin

Moss

et al. 2015

Kidney International

454

451

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Patients with advanced chronic kidney disease (CKD) have a high burden of physical and psychosocial symptoms, poor outcomes, and high costs of care. Current paradigms of care for this highly vulnerable population are variable, prognostic and assessment tools are limited, and quality of care, particularly regarding conservative and palliative care, is suboptimal. The KDIGO Controversies Conference on Supportive Care in CKD reviewed the current state of knowledge in order to define a roadmap to guide clinical and research activities focused on improving the outcomes of people living with advanced CKD, including those on dialysis. An international group of multidisciplinary experts in CKD, palliative care, methodology, economics, and education identified the key issues related to palliative care in this population. The conference led to a working plan to address outstanding issues in this arena, and this executive summary serves as an output to guide future work, including the development of globally applicable guidelines.

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Epidemiology of sleep disorders in patients with chronic renal disease in Cairo, Egypt

Abstract: The survey showed a high prevalence of sleep disruption in dialytic populations. Our data might help nephrologists to deal with patients with uremia with possible sleep disorders.

Cited by 14 publications

References 25 publications

Risk of obstructive sleep apnea among Saudis with chronic renal failure on hemodialysis

Risk of obstructive sleep apnea among Saudis with chronic renal failure on hemodialysis

Exploring sleep disorders in patients with chronic kidney disease

Executive summary of the KDIGO Controversies Conference on Supportive Care in Chronic Kidney Disease: developing a roadmap to improving quality care

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