Epidemiology of testicular cancer

Manecksha, R.P.; Fitzpatrick, John M.

doi:10.1111/j.1464-410x.2009.08854.x

Cited by 142 publications

(97 citation statements)

References 76 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…25 The high-risk group includes patients with a history of cryptorchidism, patients with a history of TGCT in the contralateral testis, patients with testicular atrophy and patients with a history of TGCT in a first-degree relative. [30][31][32][33] The interval and duration of ultrasound surveillance have yet to be defined.…”

Section: Discussionmentioning

confidence: 99%

Testicular microlithiasis an ultrasound dilemma: survey of opinions regarding significance and management amongst UK ultrasound practitioners

Shetty

Bailey²,

Freeman³

2014

BJR

View full text Add to dashboard Cite

Section: Discussionmentioning

confidence: 99%

Testicular microlithiasis an ultrasound dilemma: survey of opinions regarding significance and management amongst UK ultrasound practitioners

Shetty

Bailey²,

Freeman³

2014

BJR

View full text Add to dashboard Cite

“…Neste estudo, um adolescente apresentava criptorquidia, sendo este um dos principais fatores de risco para o desenvolvimento de neoplasias de testículo 14 . Nos relatos da literatura, a hidrocele pode estar associada ao tumor de testículo em 15 a 50% dos casos 4 .…”

Section: Discussionunclassified

Testicular tumors in children and adolescents

Neto¹,

Petrilli²,

Macedo³

et al. 2012

J Pediatr (Rio J)

View full text Add to dashboard Cite

Objective: To perform a comparative assessment of the clinical and epidemiological aspects of testicular tumors in childhood and adolescence.Methods: Retrospective analysis of medical records of patients with testicular or paratesticular neoplasms. Patients under 10 years were classified as children and patients between 10 and 20 were classified as adolescents. The obtained results were compared through the twosample test for proportions: non-parametric Mann-Whitney test and log-rank test.Results: 60 patients were admitted in the period from January 1992 to July 2009: 34 children and 26 adolescents with testicular or paratesticular neoplasms. The main manifestations were testicular tumor and scrotal pain. Pain complaints were more common in adolescents (p = 0.006), who presented a mean time from disease onset to diagnosis of 4.9 months, longer than children, who presented a period of 2.3 months from disease onset to diagnosis (p = 0.01). Histological types were as follows: germ cell tumors in 32/60 (53%), rhabdomyosarcomas (RMSs) in 23/60 (38.3%), and other in 5/60 (8.3%). Adolescents presented a higher incidence of RMSs, lymph node metastases (p = 0.003) and distant metastases (p = 0.035). Differences in survival rates among the studied patients were not statistically significant, the only indicative being that survival in RMS cases is longer for children (p = 0.072). Conclusion:Compared to children, adolescents with testicular tumor presented longer time from disease onset to diagnosis, aggressive histological type and advanced illness at diagnosis, despite the small sample analyzed. J Pediatr (Rio J) ResumoObjetivo: Avaliar comparativamente aspectos clínicos e epidemiológicos dos tumores de testículo na infância e adolescência.Métodos: Análise retrospectiva dos prontuários de pacientes com neoplasias de testículo ou paratesticulares. Foram classificados como crianças os menores de 10 anos e como adolescentes os pacientes entre 10 e 20 anos. Os resultados obtidos foram comparados por meio do teste para duas proporções: teste não paramétrico de Mann-Whitney e teste de log-rank. Resultados:No período de janeiro de 1992 a julho de 2009, foram admitidos 60 pacientes: 34 crianças e 26 adolescentes com neoplasias de testículo ou paratesticulares. As principais manifestações foram tumor e dor na bolsa escrotal. A queixa de dor foi mais comum em adolescentes (p = 0,006). Estes apresentaram tempo médio de história de 4,9 meses, mais prolongado do que crianças, com 2,3 meses (p = 0,01). Os tipos histológicos encontrados foram: tumores de células germinativas em 32/60 (53%), rabdomiossarcomas (RMSs) em 23/60 (38,3%) e outros em 5/60 (8,3%). Os adolescentes apresentaram maior frequência de RMSs, metástases em linfonodos (p = 0,003) e a distância (p = 0,035). As diferenças na sobrevida dos pacientes estudados não foram estatisticamente significantes, havendo apenas indicativo de que a sobrevida, nos casos de RMS, é maior nas crianças (p = 0,072). Conclusões:Os adolescentes com tumor testicular apresentaram maior t...

show abstract

“…For unknown reasons, the incidence of this disease has increased 3-4 fold during the last 5 decades, at least among Caucasians. 14,15 Nevertheless, in parallel with the increased incidence, a significant improvement in survival rates has been achieved and today, in the best centers, more than 95% of TGCC patients are cured. [17][18][19] Whether these diseases are fully or partially due to testosterone deficiency is so far unknown.…”

Section: Testicular Cancermentioning

confidence: 99%

Hypogonadism in young men treated for cancer

Giwercman¹,

Giwercman²

2015

View full text Add to dashboard Cite

An ever-increasing proportion of young males treated for cancer are cured. Therefore, one of the major challenges of modern Clinical Oncology is to ensure good quality of life. Cancer disease per se as well as cancer treatment may have a negative impact on androgen production, thereby leading to subclinical or clinically overt hypogonadism. Since the symptoms of androgen deficiency are rather unspecific, it is important that reproductive hormone levels be checked in young men who have been treated for cancer. As androgen deficiency in men is associated with increased long-term risk of osteoporosis as well as cardiovascular and metabolic disease, those cancer survivors who present with signs of insufficient androgen production should be followed and preventive as well as therapeutic measures, including androgen replacement therapy, should be applied according to the current guidelines.

show abstract

Epidemiology of testicular cancer

Cited by 142 publications

References 76 publications

Testicular microlithiasis an ultrasound dilemma: survey of opinions regarding significance and management amongst UK ultrasound practitioners

Testicular microlithiasis an ultrasound dilemma: survey of opinions regarding significance and management amongst UK ultrasound practitioners

Testicular tumors in children and adolescents

Hypogonadism in young men treated for cancer

Contact Info

Product

Resources

About