Epidemiology of Tetracycline Resistance Determinants in
 Shigella
 spp. and Enteroinvasive
 Escherichia coli
 : Characterization and Dissemination of
 tet
 (A)-
 1

Hartman, Antoinette B.; Essiet, Idongesit I.; Isenbarger, Daniel W.; Lindler, Luther E.

doi:10.1128/jcm.41.3.1023-1032.2003

Cited by 47 publications

(46 citation statements)

References 29 publications

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“…In a recent study developed in Shigella spp. and enteroinvasive Escherichia coli of different geographical origins, the tetB gene was more prevalent than the tetA gene (14). Our results show that the most prevalent mechanism of resistance to tetracycline among the strains we tested was tetA.…”

Section: Resultssupporting

confidence: 48%

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Mechanism of Resistance to Several Antimicrobial Agents inSalmonellaClinical Isolates Causing Traveler's Diarrhea

Cabrera

Ruiz

Marco

et al. 2004

Antimicrob Agents Chemother

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The evolution of antimicrobial resistance in Salmonella isolates causing traveler's diarrhea (TD) and their mechanisms of resistance to several antimicrobial agents were analyzed. From 1995 to 2002, a total of 62 Salmonella strains were isolated from stools of patients with TD. The antimicrobial susceptibility to 12 antibiotics was determined, and the molecular mechanisms of resistance to several of them were detected as well. The highest levels of resistance were found against tetracycline and ampicillin (21 and 19%, respectively), followed by resistance to nalidixic acid (16%), which was mainly detected from 2000 onward. Molecular mechanisms of resistance were analyzed in 16 isolates. In these isolates, which were resistant to ampicillin, two genes encoding ␤-lactamases were detected: oxa-1 (one isolate) and tem-like (seven isolates [in one strain concomitantly with a carb-2]). Resistance to tetracycline was mainly related to tetA (five cases) and to tetB and tetG (one case each). Resistance to chloramphenicol was related to the presence of the floR and cmlA genes and to chloramphenicol acetyltransferase activity in one case each. Different genes encoding dihydrofolate-reductases (dfrA1, dfrA12, dfrA14, and dfrA17) were detected in trimethoprim-resistant isolates. Resistance to nalidixic acid was related to the presence of mutations in the amino acid codons 83 or 87 of the gyrA gene. Further surveillance of the Salmonella spp. causing TD is needed to detect trends in their resistance to antimicrobial agents, as we have shown in our study with nalidixic acid. Moreover, such studies will lead to better treatment and strategies to prevent and limit their spread.

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Section: Resultssupporting

confidence: 48%

“…The intestinal tract is a suitable habitat for the acquisition of the tetA and tetB genes by horizontal gene transfer, since these tetracycline determinants are common in Enterobacteriaceae (10,14,28). In a recent study developed in Shigella spp.…”

Section: Resultsmentioning

confidence: 99%

Mechanism of Resistance to Several Antimicrobial Agents inSalmonellaClinical Isolates Causing Traveler's Diarrhea

Cabrera

Ruiz

Marco

et al. 2004

Antimicrob Agents Chemother

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“…Therefore, molecular techniques to detect resistant determinants are important methods for epidemiological studies of resistance. This technology provides important information about the transmission of resistant genes through bacterial populations [25].…”

Section: Discussionmentioning

confidence: 99%

Antibiotic resistant bacteria used as bioindicators of environmental pollution produced by tertiary treated sewage effluent

2012

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Oman depends on recycling treated wastewater as a solution to overcome the limited water supply. However, the risk of reusing recycled sewage water in the environment and public health is a major concern. Tertiary sewage treated effluent (TSE) was evaluated microbiologically from three sewage treatment plants (STPs). Mainly, all TSE from the three plants contained coliform and Escherichia coli. Multiple antibiotic resistant bacteria (MARBs) were also present in the three plants and the TSE distribution lines used for irrigation. The faecal coliform counts in the tertiary treated wastewater samples from the storage tanks of the plants fell within the acceptable limits of the Omani standards for watering public parks and landscapes. Microbial counts from the distribution lines of all plants increased significantly farther from the main TSE storage tanks. Irrigated soil from TSE revealed the presence of MARBs. Some of the isolates from the plants and irrigated soils share similar antibiotic resistance patterns but significantly at lower values. In general most of the isolates were resistant to tetracycline and ampicillin followed by streptomycin and minocycline. Presence MARBs is a clear indication of TSE pollution and can be used for biomonitoring the environment. The present systems of STPs are unreliable for complete eradication of MARBs and pathogenic bacteria.

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“…Although less reported due to its lower incidence rate and morbidity, EIEC seems to follow a similar trend. A comprehensive analysis of both Shigella and EIEC strains that were collected from North and South America, Africa, and Asia between 1970 and 2000 showed tetracycline resistance within 70 to 86% of Shigella isolates and 48% of EIEC isolates (561). Also, resistance to all first-line antibiotics was reported for an EIEC isolate in Japan (562).…”

Section: Clinical Considerationsmentioning

confidence: 99%

Recent Advances in Understanding Enteric Pathogenic Escherichia coli

et al. 2013

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SUMMARY Although Escherichia coli can be an innocuous resident of the gastrointestinal tract, it also has the pathogenic capacity to cause significant diarrheal and extraintestinal diseases. Pathogenic variants of E. coli (pathovars or pathotypes) cause much morbidity and mortality worldwide. Consequently, pathogenic E. coli is widely studied in humans, animals, food, and the environment. While there are many common features that these pathotypes employ to colonize the intestinal mucosa and cause disease, the course, onset, and complications vary significantly. Outbreaks are common in developed and developing countries, and they sometimes have fatal consequences. Many of these pathotypes are a major public health concern as they have low infectious doses and are transmitted through ubiquitous mediums, including food and water. The seriousness of pathogenic E. coli is exemplified by dedicated national and international surveillance programs that monitor and track outbreaks; unfortunately, this surveillance is often lacking in developing countries. While not all pathotypes carry the same public health profile, they all carry an enormous potential to cause disease and continue to present challenges to human health. This comprehensive review highlights recent advances in our understanding of the intestinal pathotypes of E. coli .

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Epidemiology of Tetracycline Resistance Determinants in Shigella spp. and Enteroinvasive Escherichia coli : Characterization and Dissemination of tet (A)- 1

Cited by 47 publications

References 29 publications

Mechanism of Resistance to Several Antimicrobial Agents inSalmonellaClinical Isolates Causing Traveler's Diarrhea

Mechanism of Resistance to Several Antimicrobial Agents inSalmonellaClinical Isolates Causing Traveler's Diarrhea

Antibiotic resistant bacteria used as bioindicators of environmental pollution produced by tertiary treated sewage effluent

Recent Advances in Understanding Enteric Pathogenic Escherichia coli

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