Epidemiology of Type 1 Diabetes

Maahs, David M.; West, Nancy A.; Lawrence, Jean M.; Mayer‐Davis, Elizabeth J.

doi:10.1016/j.ecl.2010.05.011

Cited by 972 publications

(786 citation statements)

References 124 publications

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“…Earlier results from the SCDR showed that 91.5% of the children had no parent with insulin-dependent diabetes, compared with 98.9% among the reference group [20]. In this study sample, boys and children with parents born in a Nordic country had a higher risk of diabetes (ESM Table 7), in accordance with previous studies on the incidence of type 1 diabetes [21,22]. In the regression analyses, we adjusted for these variables.…”

Section: Discussionsupporting

confidence: 75%

Impact of childhood-onset type 1 diabetes on schooling: a population-based register study

et al. 2013

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Aims/hypothesis We investigated the impact of type 1 diabetes on educational achievements in compulsory and upper secondary school, as well as potential long-lasting effects. Methods Altogether 2,485 individuals with type 1 diabetes, diagnosed at the age of <15 years and born in 1972-1978, were selected from the Swedish Childhood Diabetes Register, which was linked to national population registers including the Swedish Education Register. For each individual, four controls from the general population, matched for year of birth and residence at the time of diagnosis, were selected by Statistics Sweden (n=9,940). We analysed the impact of diabetes on final school grades at 16 years (compulsory school) and 19 years (upper secondary school) and on participation in the labour market at 29 years using linear, logistic, ordered logistic and quantile regression analyses, controlling for demographics and socioeconomic background. Results Diabetes had a negative effect on mean final grades (scale of 1-5) in compulsory school (−0.07, p<0.001) and theoretical programmes in upper secondary school (−0.07, p=0.001). Children with early-onset diabetes (0-4 years) suffered a greater disadvantage as a result of the disease (−0.15, p=0.001 in compulsory school). The strongest effect was seen in the lowest deciles of the conditional distribution on mean final grades. At age 29, individuals with diabetes were less likely to be gainfully employed (OR 0.82, 95% CI 0.73, 0.91). Conclusions/interpretation The small but significant negative effect of type 1 diabetes on schooling could affect opportunities for further education and career development. Attention must be paid in school to the special needs of children with diabetes.

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Section: Discussionsupporting

confidence: 75%

Impact of childhood-onset type 1 diabetes on schooling: a population-based register study

et al. 2013

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“…T1DM currently constitutes 5 to 10% of all people with diabetes globally (66,67). GM is one of the essential elements of effective T1DM management (68,69).…”

Section: Gm Strategy and Rationale By Patient Profile T1dmmentioning

confidence: 99%

American Association Of Clinical Endocrinologists And American College Of Endocrinology 2016 Outpatient Glucose Monitoring Consensus Statement

et al. 2016

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“…Better GC is associated with improved survival in patients with T1D, leading to progressive changes in the causes of mortality, particularly cardiovascular disease; therefore, it is important to identify the risk factors for cardiovascular disease in this population (25)(26)(27)(28)(29)(30)(31).…”

Section: Discussionmentioning

confidence: 99%

Dyslipidemia in young patients with type 1 diabetes mellitus

Homma

Endo

Saruhashi

et al. 2015

Arch. Endocrinol. Metab.

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Objective: The association between type 1 diabetes mellitus (T1D) and dyslipidemia (DLP) increases the risk of cardiovascular disease (CVD). The aim of this study was to evaluate the presence of dyslipidemia in young T1D patients. Materials and methods: The study design was cross-sectional and descriptive. We reviewed medical records of T1D patients followed at an endocrinology service, from 1998-2012. Data collected: gender, actual age and age at diagnosis, duration of T1D since diagnosis, body mass index (BMI), pubertal stage, glycemic control (GC) determined by glycated hemoglobin (HbA1c), total cholesterol (TC), HDL, LDL, triglycerides (TG). To analyze lipid profile and metabolic control, we used the Brazilian Society of Diabetes Guidelines. Results: Were included 239 T1D patients, 136 (56.9%) females; mean ± SD: actual age 15.7 ± 5.0 years and at T1D diagnosis 7.3 ± 3.9; T1D duration 10.6 ± 6.4 years, 86.6% puberty, 15.1% overweight. The prevalence of DLP was 72.5%, 63.3% females, 86.6% puberty, mean ± SD: actual age 15.4 ± 4.8 years and at T1D diagnosis 7.2 ± 4.1 years, duration of T1D 10.7 ± 6.1 years. We found high-CT in 56.7%, low-HDL = 21.7%, high LDL = 44.0%, high-TG = 11.8%. Between females with DLP, 83.5% was in puberty. We find correlation between the presence of DLP, a poor GC and BMC. Conclusion: We found a high prevalence of DLP in young patients with T1D, particularly in puberty females. Programs targeting the prevention of dyslipidemia should be adopted, especially for this group, in order to prevent/delay chronic complications and cardiovascular disease. Arch Endocrinol Metab. 2015;59(3):215-9

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Epidemiology of Type 1 Diabetes

Cited by 972 publications

References 124 publications

Impact of childhood-onset type 1 diabetes on schooling: a population-based register study

Impact of childhood-onset type 1 diabetes on schooling: a population-based register study

American Association Of Clinical Endocrinologists And American College Of Endocrinology 2016 Outpatient Glucose Monitoring Consensus Statement

Dyslipidemia in young patients with type 1 diabetes mellitus

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