Epidemiology, pathogenetic mechanism, clinical characteristics, and treatment of Vibrio vulnificus infection: a case report and literature review

Leng, Fei; Sun, Lin; Wu, Wei; Zhang, Jincheng; Song, Jieqiong; Zhong, Ming

doi:10.1007/s10096-019-03629-5

Cited by 51 publications

(36 citation statements)

References 51 publications

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“…The mortality rate of V. vulnificus infection is up to 60%, making it a serious public health and food safety concern (Jones and Oliver, 2009). With the global warming, this bacterium inhabits a warm environment and causes outbreaks in more areas (Rippey, 1994;Huehn et al, 2014;Bonnin-Jusserand et al, 2019;Leng et al, 2019). Thus, rapid, specific, and reliable detection methods for V. vulnificus are particularly required to facilitate better control of its spread.…”

Section: Introductionmentioning

confidence: 99%

A Real-Time Recombinase Polymerase Amplification Method for Rapid Detection of Vibrio vulnificus in Seafood

Yang¹,

Zhang²,

Wang³

et al. 2020

Front. Microbiol.

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As an important foodborne pathogen, Vibrio vulnificus gives a significant threat to food safety and public health. Rapid and accurate detection methods for V. vulnificus are required to control its spread. The conventional detection methods are time-consuming and labor-intensive, while the polymerase chain reaction (PCR)-and quantitative PCR (qPCR)-based methods are limited because of their dependence on laboratory equipment. Nucleic acid isothermal amplification technologies have been applied to develop simpler assays. In this study, a rapid detection method based on real-time recombinase polymerase amplification (RPA) targeting the extracellular metalloprotease (empV) gene of V. vulnificus has been established. The method finished the detection in 2-14 min at 39 • C with good specificity. The limit of detection was 17 gene copies or 1 colony-forming unit (CFU) per reaction, or 1 CFU/10 g of spiked food with enrichment. In a clinical sample detection test, the results of real-time RPA were 100% consistent with bioassay and qPCR. Moreover, the method could resist the effect of food matrix and could tolerate crude templates. The real-time RPA method established in this study is rapid and simple and has the potential to be widely applied for V. vulnificus detection in food safety control.

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Section: Introductionmentioning

confidence: 99%

A Real-Time Recombinase Polymerase Amplification Method for Rapid Detection of Vibrio vulnificus in Seafood

Yang¹,

Zhang²,

Wang³

et al. 2020

Front. Microbiol.

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“…For example, V. cholerae translocates a nucleator protein that increases intestinal colonization using a T3SS (Tam et al, 2007) and V. parahaemolyticus translocates effectors that regulate the activity of mitogen-activated protein kinase (MAPK) in host cells (Matlawska-Wasowska et al, 2010). All three species also utilize various decarboxylases for acid neutralization to protect the organism from conditions of low pH (Leng et al, 2019). Finally, since Vibrio spp.…”

Section: Vibrio Virulence Factorsmentioning

confidence: 99%

“…Finally, since Vibrio spp. are Gram-negative, each produces lipopolysaccharide (LPS) containing lipid A which can cause polymorphonuclear leukocytes to secrete inflammatory cytokines as well as nitric oxide, inducing vascular permeability, fever and hypotension that can lead to septic shock during infections (Leng et al, 2019).…”

Section: Vibrio Virulence Factorsmentioning

confidence: 99%

In hot water: effects of climate change on Vibrio–human interactions

Froelich

Daines

2020

Environmental Microbiology

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Sea level rise and the anthropogenic warming of the world's oceans is not only an environmental tragedy, but these changes also result in a significant threat to public health. Along with coastal flooding and the encroachment of saltwater farther inland comes an increased risk of human interaction with pathogenic Vibrio species, such as Vibrio cholerae, V. vulnificus and V. parahaemolyticus. This minireview examines the current literature for updates on the climatic changes and practices that impact the location and duration of the presence of Vibrio spp., as well as the infection routes, trends and virulence factors of these highly successful pathogens. Finally, an overview of current treatments and methods for the mitigation of both oral and cutaneous exposures are presented.

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“…Transmission occurs through ingestion of infected seafood or cutaneous inoculation. It is treated with tetracyclines (Leng et al 2019).…”

Section: Vibrio Infectionmentioning

confidence: 99%

Other Bacterial Infections of the Skin

Schaller¹

2020

Braun-Falco´s Dermatology

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The genus Corynebacterium includes morphologically similar, immovable Gram-positive rods. The one-or both-sided club-shaped swelling led to the naming (Greek koryne: club). Many species belong to the resident flora of humans and are apathogenic. They are often responsible for odors, especially in armpits and groins. Associated diseases are shown in Table 1. Cutibacterium acnes, formerly known as Propionibacterium acnes, plays an important role in acne, but is not seen as a direct cause. An association with erysipelas has been described in immunosuppressed patients. The disease spectrum of coryneform rods ranges from many harmless infections to potentially fatal diphtheria, sometimes limited to the skin.

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Epidemiology, pathogenetic mechanism, clinical characteristics, and treatment of Vibrio vulnificus infection: a case report and literature review

Cited by 51 publications

References 51 publications

A Real-Time Recombinase Polymerase Amplification Method for Rapid Detection of Vibrio vulnificus in Seafood

A Real-Time Recombinase Polymerase Amplification Method for Rapid Detection of Vibrio vulnificus in Seafood

In hot water: effects of climate change on Vibrio–human interactions

Other Bacterial Infections of the Skin

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